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What is the study of cells called?
Cytology
What are organisms made up of?
One or more cells
What is the significance of a unicellular organism?
It has independent existence and performs essential functions of life.
What is the building block of living organisms?
Cell
Who observed the first dead cell in a cork slice?
Robert Hooke
Who observed the first living cell?
Anton Von Leeuwenhoek
Who discovered the nucleus?
Robert Brown
Who proposed that all plants are composed of different cells that form tissues?
Schleiden
Who proposed that animal cells have a thin outer layer called the plasma membrane?
Schwann
Who completed the cell theory by stating that all cells arise from pre-existing cells?
Rudolf Virchow
What is the meaning of "Omnis cellula e cellula"?
All cells arise from pre-existing cells.
What is the largest known cell?
Egg of an Ostrich
What is the smallest cell?
Mycoplasma
What is the longest cell?
Nerve cell
What is the function of the semi-fluid matrix in the cell?
The main arena of cellular activities where chemical reactions occur.
What does protoplast refer to?
A cell without a cell wall, only plasma membrane and internal cellular components
What is protoplasm?
Living substance within a cell (cytoplasm + nucleoplasm)
What is a eukaryotic cell?
Cell having membrane-bound nuclei
What are examples of membrane-bound organelles?
Nucleus, Mitochondria, Plastid, ER, Golgi body, lysosome, vacuoles
What is a prokaryotic cell?
Cells that lack a membrane bound nucleus
What is the function of plasmids?
Confer unique characters such as resistance to antibiotics and are used in bacterial transformation with foreign DNA.
What are the three layers of the cell envelope?
Glycocalyx, Cell Wall, Plasma Membrane
What is the function of Glycocalyx?
Protects cells and helps in adhesion.
What is the function of the cell wall?
Gives shape and structural support, preventing cells from bursting or collapsing.
What is peptidoglycan?
The building block for the cell wall.
What is Gram staining used for?
To classify Gram-positive and Gram-negative bacteria.
What is the function of the plasma membrane?
Selectively permeable and interacts with the outside world.
What is the mesosome?
A special membranous structure formed by invagination of the plasma membrane into the cell.
What is the function of the mesosome?
Formation of cell wall, replication of DNA, cell division, respiration, secretion
What are chromatophores?
Membranous extensions into the cytoplasm that contain pigments (e.g., in cyanobacteria).
What is the composition of flagella?
Filament, Hook, and Basal body
What is the composition of prokaryotic flagella?
Flagellin protein
What is the composition of eukaryotic flagella?
Tubulin protein
What is the role of pili?
Help in conjugation (transfer of plasmid from one bacterium to the other).
What is the function of fimbriae?
Attachment
What is the function of ribosomes?
Site of protein synthesis.
What is a polysome?
A chain of ribosomes attached to a single mRNA.
What are inclusion bodies?
Non-membrane bound structures that store materials in the cytoplasm.
What is genophore?
The genetic material of prokaryotic cells (DNA).
What are the key differences between prokaryotic and eukaryotic cells?
Cell size, presence of a nuclear membrane, number of chromosomes, presence of a nucleolus, and presence of membrane-bound organelles
In cell membrane, what part is water-fearing
Hydrophobic Non-polar tail
Name Singer and Nicolson contribution to cell membrane
Proposed Fluid mosaic model of plasma membrane - in 1972
Fluid mosaic model states that membrane made up of:
Protein, Carbohydrate, Lipid
What the location of hydrophilic membrane part:
Outside
What is Lateral and Flip-Flop
Types of phospholipid movements in membrane
Protein movements, regarding Flip-Flop
No Flip-Flop movment due to the large size
Plasma membrane is:
Asymmetrical
Define Passive transport in cell membrane
No energy needed, osmosis an diffusion, follows concentration gradient
Define Active transport in cell membrane
Need energy ATP, goes against concentration gradient
Define Endocytosis
Intake of materials in the form of Carrier vesicles formed by invagination plasma membrane
Two types of endocytosis:
Pinocytosis and Phagocytosis
Define Exocytosis
Discharge undigested waste products to outside of the cell through plasma membrane, AKA Cell vomiting / Ephagy
Composition of cell wall - Bacteria
Peptidoglycan
Composition of cell wall - Fungi
Chitin
Composition of cell wall - Algae
Cellulose, galactans, mannans and minerals like calcium carbonate
Composition of cell wall - Plant
Cellulose, Hemicellulose Pectin and proteins
Endomembrane System includes
Endoplasmic reticulum, Golgi complex, Lysosome, Vacuoles
What is Extends From nuclear membrane to plasma membrane
Endoplasmic Reticulum
ER is composed of
Cisternae, Tubules, Vesicles
Where are actively protein synthesis cells found:
Pancreas and brain cell
Ribophorin-I and Ribophorin - II locations:
Cisternae
Lipid and sterol synthesis locations:
Tubules
Muscle cell sarcoplasmic reticulum
SER. Smooth Endoplasmic Reticulum
Camillo golgi observed:
Golgi apparatus
cis Face of Golgi apparatus:
Take unmodified protein
Trams Face of Golgi apparatus:
After modification protein discharged From the trans Face
Golgian Vacuoles with hydrolytic enzyme is Called
Lysosome
Acidic condition of lysosome maintained by
H+ ATPase Pump
Multiple Forms of lysosomes known as
polymorphism
Tonoplast
Single membrane bound that surrounds Vacuole
Mitochondria Shape
cylindrical or Sausage
Janus green stains
Mitochondria
ATP is made mainly in Mitochondria or outer membrane
Inner membrane
Diameter of mitochondria
0.2 to 1.0 μm
length of mitochondria
1.0 to 4.1 μm
Protein factories
Ribosomes
George Palade C1953 discovered
Ribosomes
Svedberg unit measures:
ribosome on density
Plastids are
Found in eukaryotic autotrophs like Plant and Euglenoides
Leucoplasts
Colourless, occur near nucleus in non-green cell, store starch.
Elaioplasts
Store Fats and oil
Aleuroplasts
Store proteins
Chromoplasts
Contain carotene, xanthophylls like pigment
Chloroplasts
Possess photosynthetic pigments
Where are chloroplasts Found:
Mesophyll cells of leaves
Thylakoid membrane is analogous to:
cristae in mitochondria
Cytoskeleton composition
Microtubules, Micro Filaments, Intermediate Filament proteinaceous structure
Cartwheel like organization
Centrosome
Basal bodies rise from
Centrioles
cillia and Flagella internal organization is:
similar in Eukaryot
Microbodies types:
Sphaerosome, Glyoxysomes, Peroxisomes
Sphaerosome function:
Storage and synthesis of fats, AKA Plant lysosomes
Spherical sac-like structure Found in both plant and animal cell, contain enzymes
Peroxisomes
Double membrane bound structure brain of cell is
Nucleus
Flemming discovered:
Chromatin
Lack of nucleus state called
Anucleate
Two nuclei per cell state called
Binucleate
Many nuclei state called
Multinucleate
rRNA factory is
Nucleolus
Lampbrush chromosome discovered by
J. Ruckert