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Acromegaly
too much GH after growth plates close (usually pituitary tumor)
Acromegaly key signs/symptoms
enlarges hands/feet/face, joint pain, headaches
Acromegaly care/management
treat tumor, control GH levels
Addison’s disease
adrenal cortex doesn’t make enough cortisol/aldosterone
Addison’s disease key signs/symptoms
fatigue, weight loss, low BP, salt craving, hyperpigmentation
Addison’s disease care/management
lifelong steroid replacement
Cushing’s syndrome
too much cortisol (0ften from meds or pituitary/adrenal tumor)
Cushing’s syndrome key signs/symptoms
truncal obesity, “moon face,” thin skin/bruising high glucose
Cushing’s syndrome care/management
lower steroid dose or treat tumor
Gigantism
too much GH before growth plates close (pituitary tumor)
Gigantism key signs/symptoms
excessive height and growth in children
Gigantism care/management
treat tumor; control GH levels
Hirsutism
excess androgens in females (often PCOS; meds/tumors possible)
Hirsutism key signs/symptoms
excess facial/body hair, acne, irregular periods
Hirsutism care/management
treat cause; hair removal; meds to reduce androgens
Hyperthyroidism
too much thyroid hormone (often Graves disease)
Hyperthyroidism key signs/symptoms
weight loss, heat intolerance, rapid/irregular heartbeat, anxiety
Hyperthyroidism care/management
antithyroid meds, RAI, or surgery
Hypothyroidism
too little thyroid hormone (often Hashimoto’s)
Hypothyroidism key signs/symptoms
fatigue, weight gain, cold intolerance, slow HR
Hypothyroidism care/management
levothyroxine replacement
Graves’ disease
autoimmune hyperthyroidism
Graves’ disease key signs/symptoms
goiter, eye findings (exophthalmos), heat intolerance
Graves’ disease care/management
antithyroid therapy, eye care if needed
Diabetes insipidus
low ADH or kidneys don’t respond to ADH
Diabetes insipidus key signs/symptoms
extreme thirst, large volumes of dilute urine
Diabetes insipidus care/management
Desmopressin (central DI), treat cause
Diabetes mellitus-Type 1
Autoimmune destruction of B-cells, no insulin
Diabetes mellitus-Type 1 key signs/symptoms
Polydipsia, polyuria, weight loss, high glucose
Diabetes mellitus-Type 1 care/management
Insulin therapy, glucose monitoring
Diabetes mellitus-Type 2
insulin resistance + low insulin over time
Diabetes mellitus-Type 2 signs/symptoms
often overweight, high glucose, fatigue
Diabetes mellitus-Type 2 care/management
lifestyle changes, oral meds, insulin if needed
Diabetes mellitus-Gestational
glucose intolerance during pregnanacy
Diabetes mellitus-Gestational signs/symptoms
high maternal glucose, fetal risks
Diabetes mellitus-Gestational care/management
diet, monitoring, meds if needed
Blood serum testing
TSH, T3, T4, insulin, glucose, etc.
Thyroid scan
radioactive iodine to view structure/function
Radioactive iodine uptake test
evaluates thyroid activity
Hormone level monitoring
cortisol, ACTH, growth hormone
Surgical Procedures
thyroidectomy, adrenalectomy, parathyroidectomy
Endocrinologist
diagnoses and treats hormone disorders
Thyroid specialist
focused on thyroid disease
Diabetes specialist
manages diabetes care