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neurons or nerve cells
they are separated differently to other cells, as tehy communicate with one another through synapses
they are constantly active and motor our internal and external environment, creating mental experiences and control behavior
they work together
central nervous system
made up by brain and spinal cord, they integrate and syntehsize neural information
peripheral nervous system
made up of nerves which relays information to and from the brain to other parts of teh body
neuron
a single cell of teh nervous system
nerve
a bundel of neurons within teh peripheral system
sensory neurons
bundled together to form nerves carrying information form sensory organs into central nervous system
motor neurons
bundled neurons into nerves carrying messages out from central nervous system to operate muscles and glands
interneurons
exist only in central nervous system and carry messages from 1 set of neurons to another
they collect, organize, and integrate messages from various sources
cell body
widest part of a neuron it contains the cell nucleus and other basic machinery common to all bodily cells
dendrites
thin, tube-like extensions which branch and function to receive input to neuron
motor and sensory neuros; etend directly off teh cell body and branch out to form bushlike structures to increase surface area of cell and increase signal recieving
sensory; branch out form one axon, expanding into sensory organ and repsonds to signals
axon
thin tube-like etension from cell body which carries messages to other neurons or for motor-neurons to muscle cells
axon terminal
most axons form many branches some distance from teh cell body, and each branch ends with a small swelling called the axon terminal. tehy release chemical transmitter molecules onto neurons or muscle cells
myelin sheath
axons of some neuron are surrounded by a casing, myelin sheath, which is a fatty substance produced by glial cells. it helps to speed up the movement of neuron pulses
action potentials
wave of charge in electrical charge across the axon membrane. Initiated by a chance in structure of cell membrane at one end of axon; thousands of channels open up allowing more NA+ions to move, enough travel inwards causing a temporary postive charge
motor and interneurons: triggered at the junction between the cell body and the axon, they travel rapidly across the axon to the terminal
sensory; triggered at the dendritic end of axon and travel through or past the cell body to the terminal
same strength buy varying rates, thus a neuron varies the strength of its effect on neurons or muscle cells
cell membrane
encloses each neuron, a sporus skin. it permits certain chemicals to flow into and out of cell while blocking others
intracellular fluids
in neuron a solution with water and dissolved chemicals
extracellular fluid
outside of neuron solution of water and dissolved chemicals
soluble protein molecules A-
with negative charge in intracellular fluid K+, NA+ and Cl- in extracellular fluid
resting potential
the negative charge inside and positive charge outside creates and electrical charge across membrane, making action potential possible
depolarization phase
the sudden electrical shift of action potential, the channels close na+ but not for K+, creating a temporary postive charge inside
repolarization phase
the channels close na+ but not for K+ however due to temporary chance the K+ are repelled by positive charge inside and thus pushed outwards, returning to normal charge
sodium potassium pump
each membrane has one that moves sodium out and potassium in
cells threshold
sodium channels open in response to depolarizations when equal to the same critical value
speed of action potential
influenced by the large diameter, less resistance thus increases speed. also influenced by the myelin sheath, the thicker the better the rate which neuron pulses can be sent increases
myelination
process of developing myelin begins before birth but not done until into adulthood, neurons in sensory system do it first then motor nerves
synapse
the junction between each axon terminal and the cell body or dendrite or receiving neuron
neurotransmitter
when an action potential reaches an axon terminal it causes the terminal to release a packets of a chemical substances, they move across the space between cells and alter the receiving neurons which influence its production of action potentials, increasing or decreasing the likelihood of a neuron to fire
parkinson’s
muscle tremors and severe difficulty in initiating and coordinating movements caused by degeneration of dopamine-producing neurons whose axons originate and terminate in specific brain areas
synaptic cleft
seperates the axon terminal from the membrane of the cell that it influences
presynaptic membrane
the membrane of the axon terminal that faces the cleft
postsynaptic cleft
the cell on the other side of the cleft
vesicles
a small fluid-filled bladder in the body, each contain several thousand molecules of chemical neurotransmitters
dopamine
infleunce’s movement and motivated behavior, high levels = schizophrenia, low levels = parkinsons
acetylcholine
released at neuromuscular junction associated with the activation of muscles within brain, alter the way other brain structures process information
neuromodulator
alter the way other brain structures process information
serontonin
influence sleep and mood
GABA
gamma-aminobutyric acid, slows or weakens neuron signals anxiety
How do neurotransmitter molecules move across the synaptic cleft?
They diffuse through the fluid in the cleft.
What happens when neurotransmitter molecules reach the postsynaptic membrane?
They attach to special receptors on the postsynaptic membrane. Opening ion channel, allowing ions to pass through.
What effect does ion flow have on a muscle cell?
It triggers a biochemical process that causes the muscle cell to contract.
What effect does ion flow have on a postsynaptic neuron?
It changes the polarization of the neuron,
excitatory synapse
the trasmmitter opens ino channells for NA+ in postsynaptic membrane, causing depolarizatoin of receiving neuron, more positive which increases rate of action potentials
inhibitory synapse
transmitter opens fro CL- and K+ causing hyperpolarization, more negative, drcreaisng rate of action potentails
neruogensis
process of creating new neurons for the first 2 weeks after conception
differentation
last stage of neuron development , they grow in size and increase number of dendrites and axon terminal and number of synapses formed
selective cell death/ apoptosis
neurons die =, so do synapses not not this process, which begins before birth and continuous into teen years
mirror neurons
organized systems of neurons that are designed to faster social learning, help us behave in ways that mirror what we observe. They are important in imitative learning, where the specific behaviors a model performs are as important as the goal the model attains.
They may allow you to understand another’s intentions, which is important for social cognition
Methods to identify the functions of the brain
observing behavioral deficits that occur when a part of the brain is destroyed or is temporarily inactivated
observing behavioral effects of artificially stimulating specific parts of the brain
recording changes in neural activity that occur in specific parts of the brain when a person or animal is engaged in a particular mental or behavioral task
Electroencephalography (EEG)
Analyzing Electrical Brain Activity
Recording of the electrical activity of the cortex using multiple scalp electrodes.
Event-Related Potentials (ERPs)
Analyzing Electrical Brain Activity
An encephalographic measure of local changes in the brain electrical activity in response to specific stimuli.
Magnetoencephalography (MEG)
Analyzing Electrical Brain Activity
Detects the magnetic field changes produced by the cortical electrical activity.
Transcranial Magnetic Stimulation (TMS)
Analyzing Electrical Brain Activity
The localization of a brain function by temporarily blocking the electrical activity of an area by exposure to a magnetic field.
TMS uses magnetic pulses from a coil placed on the scalp to temporarily disrupt neuronal activity, mimicking a reversible brain lesion. It’s used to map functions of the cerebral cortex.
TMS can be used to show the functional connections between specific areas within movement-control portions of the cerebral cortex and the muscles controlled by those areas.
Transcranial Direct Current Stimulation (tDCS)
Analyzing Electrical Brain Activity
The localization of brain function by temporarily stimulating electrical activity directing weak electrical currents to specific areas of the brain.
it has been found to alter perceptual, cognitive, and motor functioning. tDCS has also been effective in alleviating some brain disorders
Magnetic Resonance Imaging (MRI)
Analyzing Anatomical Structure
High-resolution image of brain anatomy measuring energy changes of brain tissue after an exposure to a strong magnetic field.
Diffusion Tension Imaging (DTI)
Analyzing Anatomical Structure
Measures the diffusion of water in the brain tissue, permitting the imaging of the white matter tracts.
Positron Emission Tomography (PET)
Analyzing Functional Metabolic Activity
Assesses the metabolic activity of glucose or oxygen in the brain by following the path of a radioactive tracer injected intravenously.
Functional Magnetic Resonance Imaging (fMRI)
Analyzing Functional Metabolic Activity
Assesses indirectly the metabolic activity of the brain through measuring the changes of the blood flow.
flexion reflex
contraction of flexor muscles, which bend limb at each joint, causing it to be pulled toward the body
it occurs fast as it doe snot require the brain
examples of TMS
Sara Torriero, 2007
interested in neural foundation of observeable learning; learning form watching others
one group of students received TMS on dorsolated prefrontal cortec, right before watching someone solve. aproblem and were unable to have observable learning
electroencephalogram, EEE
used as an index wheter a person is aurosed, relax, or asleep
even related potential, ERP
brief change in EEE after stimulus, comparing average ERP with different scalp locations, reveals a pattern of activty in brain as person responds so stimulus
activation of the brain
blood vessels enlarge so more blood enters, whcih carry oxygen and glucose, supplying enough energy sources to increase neural atcivty
postron emission topography
1st neuroimaging method in 1970, enjecting radioactive substance into blood, measuing the radioactivty that is emitted from each part of the brain
functional magnetic resoure imaging fMRI
1990, creating magnetic field around teh person’s head, causing hemoglobin molecules that carry oxygen in teh blood to give off radio waves of a certain frequency
\these are then detected to asses teh amount of blood in each part of the brain
lesions
areas fo damage in brain
producing lesion electrically
thin wire electrode, insulted everywhere except for teh top, is surgically inserted in brain and currents ent through to destroy neurons next to tip
helps to identify different brain nuclei which are crucial for basic motivational and emotional states
producing lesion chemically
thin tube, cannula, inserted in brain and small amount of chemical injected to destory neurons whose cell bodies are close to it
helps to identify different brain nuclei which are crucial for basic motivational and emotional states
electrical stimulation
thin wire electrode has a weaker current than for lesions, but it produces action potentials
it is activated through radio waves
exhibit drive and emotional states
chemical stimulation
a cannula placed permantely and before behavioral testing, a tiny amount of a neurotransmitter substance or other chemical activates neurons
exhibit drive and emotional states
sensory-perceptual hierarchy
involved in data-processing receiving sensory data about internal and external environment, it analyses for the bodily needs
bottom= sensory receptors
top = perceptual centres in brain
motor-control hierarchy
involved with teh control of movement
top= executive centres making decisions about the activity the person should engage in, what muslce to use
bottom= translate those decisions into patterns of muscle movements
nerve classes
cranial nerves: proect directly from brain
spinal nerves: project diretcly from psinal cord
roles and patterns of action potentials
the action potentials from teh sensory neurons are the data that perceptial areas of central nervous system use to understand teh internal and external state
somatosensation
sensation conveyed by physical sensation, pain etc
skeletal muscles
muscles that are attahced to bones and produce externally observed movement of body, when contracted
make up somatic, body, part of peripheral motor system
they initiate activity
visceral muslces and glands
muslces attached to bones and dont move skeletal when contracting
glands structures that produce secretion such as salivary glands or sweat glands
they make up autonomic portion of peripheral motor system
they modulate not inititate
sympathetic diviison of autonomic system
responds to stressful stimulation and helps prepare body for ‘fight ro flight’ situation
increase in heart rate and blood pressure, higher energy, increase blood flow, and inhibition fo digestion processes
parasympathteic divions of autonomic system
serves regenerative, energy conserving functions, with opposite effects of sympathetic division
ascending tracts
in spinal cord which carry somatosensation information through spinal nerves to brain
descending tracts
carry motor control commands from brain through spinal cord to muscles