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Agonist
Drug that binds and activates the receptor to trigger and enhance an intended response
Analgesics
Drugs that relieve pain without causing a loss of consciousness
Anaphlaxis
Condition of shock caused by hypersensitivity to a drug or other substance that results in life threatening respiratory distress and vascular collapse
Anemia
subnormal concentration of erythrocytes or hemoglobin in the blood
Anestetics
Agents that reversibly depress neuronal function, producing loss of ability to perceive pain and or other sensations
Angina Pectoris
severe constricting pain in the chest, often radiating to the shoulder and down the arm, caused by ischemia (obstruction of blood supply) of the heart muscle, usually a result of coronary disease
Antagonist
Drug that binds to the receptor and completely or partially blocks the activation of a biological response
Anticholinergics
Drugs that block the passage of impulses through the parasympathetic nerves
Arrhythmias
Variations from the normal rhythm of the heartbeat
Atherosclerosis
Condition in which thickening of the wall of a blood vessel occurs because of the deposition of plaque
Bronchodilators
Drugs that cause expansion of the lumina of the air passages of the lungs
Coagulation
Process of clot formation
Contraindications
Conditions that render the administration of some drug or some particular line of treatment improper or undesirable
Diabers mellitus
Primarily a disorder of carbohydrate, protein, and fat metabolism secondary to insufficient secretion of insulin or insulin resistance
Diabetic Gastroparesis
form of nerve damage that affects the stomach; food does not move through the stomach in a normal way, resulting in vomiting, nausea, or bloating
Diabetic peripheral neuropathy
Disorder of the peripheral nervous system, a complication of diabetes
Diuretics
Drugs that promote the excretion of urine
Drug
Any substance that, when taken into a living organism., may modify one or more of its functions
Edema
Presence of abnormally large amounts of fluid in the tissues of the body
Gastroesophageal reflux disease
Inflammation of the lower esophagus from regurgitation of acid gastric contents; symptoms include heartburn
Generic Name
Drug name that is usually descriptive of its chemical structure but is not protected as is a brand or trade name
Hematoma
Localized collection of blood in the tussue resulting from a break in the wall of the blood vessel
Hypertension
Persistently high arterial blood pressure, usually exceeding 140/90 mmHg
Idisyncratic Reaction
Response to a drug that is not normative per its intended action or side effects
Inhalant
Breathable chemical vapor that may cause systemic local effects
Infiltration
Diffusion of lfuid into a tissue; often used interchangeably with extravasastion
Laxatives
Agents that promote evacuation of the bowel
Narrow Therapeutic Index Drugs
Drugs for which small changes in dose or blood concentration can cause serious therapeutic changes and or adverse reactions
Microorganisms
Microscopic organisms such as bacteria or viruses
Opioids
Drugs natural or synthetic that have pain relief activity example being morphine
Osteoporosis
Disease of bone that leads to an increased risk for fracture; bone mineral density is reduced and bone microarchitecture is disrupted
Parenteral
Not through the gastrointestinal tract but by injection
Parkinson Disease
Degenerative neurlogic disease of the brain that often impairs motor skills speech and other functions
Peristalsis
Waves of conrtaction that propel contents through the gastrointestinal tract
Pharmacist
Person who is licensed to prepare and dispense drugs
Pharmacokinetics
study of the metabolism and action of drugs with particular emphasis on the time required for absorption, duration of action, distribution in the body, and method of excretion
Pharmacolgy
Study of drugs and their origin, nature, properties, and effects on living organisms
Physical Dependence
State of adaption exhibited by a withdrawal syndrome specific to a class of drugs and that may be produced by abrupt cessation, rapid dose reduction or administration of an antagonist
Shizophrenia
Chronic mental disorder characterized by period of hallucinations and paranoia
Shock
condition characterized by profound hypotension and reduced tissue perfusion
Side effect
Consequence other than the one for which a drug is used
Therapeutic
Pertaining to the art of healing
Thromboembolic Disorders
Conditions involving the partial or complete obstruction of a blood vessel
Tolerance
State of adaption in response to drug exposure that results in a decrease of one or more of the drugs effects over time
Vasoconstrictors
Drugs that cause constriction of the blood vessels
Vasodilators
drugs that cause dilation of the blood vessels
Ampule
small sealed glass container that holds a single dose of parenteral solution in a sterile condition
Angiocath
Catheter inserted directly into the vein for drug administration
Bolus
Concentrated mass of pharmaceutical preparation
Buccal
Pertaining to the inside of the cheek
Drip infusion
Intravenous infusion of a large amount of fluid over a certain period
Enteral
Within the gastrointestinal tract
Extravasation
Discharge or escape of fluid from a vessel into the surrounding tissue that can cause localized vasoconstriction, resulting in sloughing of tissue and tissue necrosis of not reversed with an antidote
intradermal
Within or between the layers of skin
Intramuscular
Within the muscle tissue
Intravenous
Within a vein
Intravenous injection
Medication that is delivered by intravenous push or intravenous infusion directly into the vein
Parenteral or Parenterally
Drug administration by a rout other than the gastrointestinal tract typically by injection through the skin
Rectal
Inserted into the rectum
Subcutaneous
Beneath the skin
Sublinqual
Beneath the tongue
Topical
Applied to a certain area of the skin and affecting only the area to which it is applied
Transdermal
Enterin through the skin
Venipucture
Puncture of a vein
Vial
Small glass bottle containing multiple doses of a drug
Acid Group
Contains carbon double bonded to an oxygen single bonded to another oxygen and a negative charge at the pH of the body
Amine Group
Contains nitrogen bonded to two hydrogen atoms
Anaphylactoid
Resembling an immune system response to foreign material
Atomic Numbers
Numbers of protons in the nuclei of the different elements
Blood Urea Nitrogen
BUN test can reveal whether the urea nitrogen levels are higher than normal suggesting that the kidneys or liver may not be working properly
Bond
Interactions between electrons of atoms that hold the atoms together in a stable group; line drawn between atoms indicates a bond
Bronchospasm
Involuntary constriction of the bronchial tubes usually resulting from an immune system reaction to a foreign particle or molecule
Compound
a substance composed of two or more elements combined in a definite ratios that give the substance specific properties
Contraindictions
Factors of a patients history or present status that indicate that a medical procedure should not be performed or that a medication should not be given
Dimer
Compound formed by bonding of two identical simpler molecules
Extravasation
Leakage from a vessel into the tissue
Flocculation
Formation of flaky masses resulting from precipitation or coming out of a suspension or solution
Histamine
molecular substance containing an amine group; causes bronchial constriction and a decrease in blood pressure
Hydroxyl
Common chemical group, part of the water molecule, containing one atom of hydrogen and one atom of oxygen; carries a negative charge (anion) when not a part of a molecule
Ionic
atom or molecule having a negative charge (anion) or positive charge (cation)
Methyl Groups
Common biochemical groups containing one carbon atom and three hydrogen atoms
Molecules
Stable groups of bonded atoms having specific chemical properties
Monomer
Simple molecules of a compound of relatively low molecular weight
Osmolality
measurement of the number of particles (molecules or ions or cations) that can crowd out water molecules in a measured mass (kilogram) of water
Osmosis
Movement of water from an area of high concentration to an area of low concentration through a semipermeable membrane such as blood vessel walls and cell membranes
pH
relative acidity or basicity(alkalinity) of a solution; pH below 7.0 is acidic and has more hydrogen cations than hydroxyl anions whereas pH above 7.0 is alkaline and has more hydroxyl anions than cations
Radiopharmaceutical
Pharmaceutical compound that is attached to a radioisotope
Shock
Inadequate blood flow within the body with resulting loss of oxygen and therefore energy
Solution
Uniform mixture of two or more substances composed of molecule sized particles that do not react together chemically
Suspension
Nonuniform mixture of two or more substances one of which is composed of larger than molecule size particle that have a tendency to cluster together
Ultrasound Contrast agents
exogenous substances that can be administered to a patient to enhance ultrasonic signals These can be administered either in the blood pool or in a cavity of the body
Autonomy
Person's self reliance, independence, liberty, rights, privacy, individual choice, freedom of the will and self contained ability to decide
Beneficence
doing of good; active promotion of goodness, kindness, and charity
Caring
Care for; an emotional commitment to and a willingness to act on behalf of a person whit whom a caring relationship exists
Codes of Ethics
Articulated statements of role morality as seen by the members of a profession
Confidentiality
Belief that health related information about individual patients should not be revealed to others; maintenance of privacy
Consequentialism
belief that the worth of actions is determined by their ends or consequences; actions are right or wrong according to the balance of their good and bad consequences
Duties
obligations placed on individuals, groups, and institutions by reason of the so-called moral bond of our interdependence with others
Ethical Dilemmas
Situations requiring moral judgment between two or more equally problem fraught alternatives; two or more competing moral norms are present, creating a challenge about what to do
Ethical Outrage
Gross violation of commonly held standards of decency or human rights