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What is not involved in Pharmacokinetics?
drug administration
drug bioavail
metabolism
onset, duration & intensity of drug
Onset, duration & intensity of drug
What is pharmacodynamics?
the actions of drug on body
excretion
biotransformation
absorption
the actions of a drug on the body
What parenteral route is 100% bioavailability?
IV
What substances can cross the Blood Brain Barrier?
Lipid Soluble substances and water
What state of drugs exert a biological effect?
Free state
What is the most important excretory organ for drugs?
Kidney
What is the major site of metabolism of many drugs?
The liver
What is the first order elimination kinetics?
elimination of drug is proportional to drug concentration
What is zero order elimination kinetics?
elimination of constant quantity of the drug per unit of time
What is the half life of a drug?
time taken for plasma concentration of a drug to reduce to half of its original value