Chapter 21: Miscellaneous Bacterial Agents of Disease

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5 Terms

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Spirochetes and Genus Treponema

• Thin, regular, coiled cells

• Live in the oral cavity, intestinal tract, and perigenital regions of humans and animals

• Pathogens are strict parasites with complex growth requirements

• Require live cells for cultivation

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Treponema Pallidum

Causes Syphilis

  • Human is the natural host

  • Extremely fastidious (hard to grow) and sensitive; cannot survive long outside of the host

  • Sexual and transplacental transmission (crosses the placenta)

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Primary Syphilis

  • Initial appearance of chancre at inoculation site

  • Intense treponemal activity in body

  • Chancre later disappears

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Secondary Syphilis

  • Spirochete is multiplying in the bloodstream

  • Rash forms on the skin, palms and soles with fever, headache and sore throat

    • Rash does not hurt or itch

    • Can persist for months

    • Disappears spontaneously

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