OVERACTIVE BLADDER (OAB)/ Benigh Prostate Hyperplasia (BPH)/ Erectile Dysfunction (ED) AGENTS

Oxybutynin

Ditropan XL, Oxytrol, Gelnique — Anticholinergic agent

Oxybutynin PO/Function/Common Use

PO — Reduces bladder muscle spasm — Overactive bladder (urinary incontinence)

Oxybutynin Adverse Drug Reactions/Special Considerations

— — Dry mouth, dry eyes, constipation, blurred vision, urinary retention

Solifenacin

Vesicare — Anticholinergic agent

Solifenacin PO/Function/Common Use

PO — Reduces bladder muscle spasm — Overactive bladder (urinary incontinence)

Solifenacin Adverse Drug Reactions/Special Considerations

— — Dry mouth, dry eyes, constipation, blurred vision, urinary retention

Tolterodine

Detrol — Anticholinergic agent

Tolterodine PO/Function/Common Use

PO — Reduces bladder muscle spasm — Overactive bladder (urinary incontinence)

Tolterodine Adverse Drug Reactions/Special Considerations

— — Dry mouth, dry eyes, constipation, blurred vision, urinary retention

Doxazosin

Cardura — α1-blocker

Doxazosin PO/Function/Common Use

PO — Dilates the urethra and arteries — BPH, hypertension

Doxazosin Adverse Drug Reactions/Special Considerations

Hypotension (low blood pressure) — Headache, dizziness, back pain, weakness

Tamsulosin

Flomax — α1-blocker

Tamsulosin PO/Function/Common Use

PO — Dilates the urethra — BPH

Tamsulosin Adverse Drug Reactions/Special Considerations

— — Headache, dizziness, back pain, weakness

Terazosin

Hytrin — α1-blocker

Terazosin PO/Function/Common Use

PO — Dilates the urethra — BPH

Terazosin Adverse Drug Reactions/Special Considerations

— — Headache, dizziness, back pain, weakness

Dutasteride

Avodart — 5-α reductase inhibitor

Dutasteride PO/Function/Common Use

PO — Reduces dihydrotestosterone (DHT) synthesis — BPH

Dutasteride Adverse Drug Reactions/Special Considerations

— — Decreased libido, erectile dysfunction, breast tenderness — May take as much as 6 months for maximum effects

Finasteride

Propecia, Proscar — 5-α reductase inhibitor

Finasteride PO/Function/Common Use

PO — Reduces dihydrotestosterone (DHT) synthesis — BPH

Finasteride Adverse Drug Reactions/Special Considerations

— — Decreased libido, erectile dysfunction, breast tenderness — May take as much as 6 months for maximum effects

Sildenafil

Viagra, Revatio — Phosphodiesterase-5 (PDE) inhibitor

Sildenafil PO/Function/Common Use

PO — Dilates arteries in selected areas — Erectile dysfunction (Viagra), pulmonary hypertension (Revatio)

Sildenafil Adverse Drug Reactions/Special Considerations

Low blood pressure when taken with nitrates; priapism (erection lasting >6 hours) — Headache, back pain, abnormal vision, flushing — Do not take with any nitrate

Tadalafil

Cialis, Adcirca — Phosphodiesterase-5 (PDE) inhibitor

Tadalafil PO/Function/Common Use

PO — Dilates arteries in selected areas — Erectile dysfunction, BPH

Tadalafil Adverse Drug Reactions/Special Considerations

Low blood pressure when taken with nitrates; priapism (erection lasting >6 hours) — Headache, back pain, abnormal vision, flushing — Do not take with any nitrate

Vardenafil

Levitra, Staxyn — Phosphodiesterase-5 (PDE) inhibitor

Vardenafil PO/Function/Common Use

PO — Dilates arteries in selected areas — Erectile dysfunction

Vardenafil Adverse Drug Reactions/Special Considerations

Low blood pressure when taken with nitrates; priapism (erection lasting >6 hours) — Headache, back pain, abnormal vision, flushing — Do not take with any nitrate