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metric system
-most logically organized
-never use a trailing zero, but always use a leading zero in front of the decimal point
household system
-most familiar to individuals
-disadvantage of inaccuracy
solutions
solid dissolved in fluid, concentration is expressed as:
-units of mass/units of volume (g/L, mg/mL)
-percentage (10% solution)
-proportions (1/1000)
chemical medication name
provides the exact description of medication's composition
generic medication name
listed in the U.S. Pharmacopeia
trade medication name
brand or proprietary name. This is the name under which a manufacturer markets the medication.
effect of medication on body system; symptoms the medication relieves; medication's desired effect
What are three ways medications are classified?
medication forms
Solid, liquid, other oral forms; topical, parenteral; forms for instillation into body cavities
absorption, distribution, metabolism, excretion
What are the four factors of pharmacokinetics?
absorption
passage of medication molecules into the blood from the site of administration
factors that influence absorption
- Route of administration
- Ability of the medication to dissolve
- Blood flow to the site of administration
- Body surface area
- Lipid solubility
distribution
-circulation
-membrane permeability
-protein binding
metabolism
biotransformation occurs under the influence of enzymes that detoxify, break down, and remove active chemicals
excretion
medications exit the body through various routes
therapeutic effect
Type of Medication Action: expected or predicted physiological response
adverse effect
Type of Medication Action: unintended, undesirable, often unpredictable
includes side effect, toxic effect, idiosyncratic reaction, and allergic reaction
side effect
Type of Medication Action: predictable, unavoidable secondary effect
toxic effect
Type of Medication Action: accumulation of medication in the bloodstream
idiosyncratic reaction
Type of Medication Action: overreaction or under-reaction or different reaction from normal
allergic reaction
Type of Medication Action: unpredictable response to a medication; can be mild or severe (anaphylactic)
medication interactions
one medication modifies the action of another
medication tolerance
more medication is required to achieve the same therapeutic effect
medication dependence
Physical or psychological reliance on a medication
medication timing
therapeutic range, peak, trough, half-life, plateau, time-critical medication, patient teaching
oral routes
-swallow or tube (pills, liquid)
-sublingual administration
-buccal administration
topical routes
skin and mucous membranes
inhalation routes
A route of drug administration through the respiratory system where the large surface area and high vascularity cause a rapid response.
parenteral routes
ID, SUBQ, IM, IV
miscellaneous routes
epidural, intrathecal, intraosseous, intraperitoneal, intrapleural, intraarterial
medication safety checks
1. Before you pour or remove the medication from the drawer.
Check the medication label against the MAR.
2. After your pour or remove the medication.
Verify the label against the MAR.
3. At the bedside before administering.
Check the medication again.
Verify at the bedside w/the MAR and use at least 2 identifiers.
medication errors
any preventable event that may cause inappropriate medication use or jeopardizes patient safety
common incidents victim to medication errors
chronic lower respiratory diseases, accidents, stroke, Alzheimer's disease, DM
A. Assess
B. HCP
C. incident report
D. reconcile
Nurse's Role in Medication Errors
Determine effect on patient and intervene to offset any adverse effects of the error.
1. (A) the patient's condition.
2. Notify the (B).
3. Prepare and file an (C)
-Report near misses and incidents that cause no harm
-During transitions in care, (D) medications
medication, dose, patient, route, time, documentation
Identify the six rights of medication administration.
Medication Safety Check Considerations
-check 3x
-check expiration date
-always clarify unclear medications
-open meds in front of patient
-advise them what you're administering as you go
Nursing Assessment Before, During, and Following Administration of Medication
history, allergies, medications, diet history, perceptual/coordination problems, current condition (BP, LOC), attitude about medication use, learning needs
medication prescribers
Physicians, nurse practitioners, physician's assistants
medication orders
written, verbal, telephone
medication abbreviations
-can cause errors; use cation
-know prohibited and error-prone abbreviations
types of orders in acute care agencies
Standing or routine
PRN
Single (one-time)
STAT
Now
Prescriptions
standing medication orders
A set of prewritten orders that a nurse can use to administer treatments and meds and is usually written by a specific practitioner, which allows nurses to administer certain meds; can be used until cancellation or expiration of treatment plan
PRN orders
Similar to standing orders, except that orders of this type are executed according to the patient's needs.
single (one-time) orders
medication to be given once at a specified time
STAT orders
given immediately in an emergency
now orders
- 90 minutes to give medication
- 1 time order
Nurse's Role In Medication Administration
Determines medications ordered are correct
-use clinical judgment; if medication dose & route prescribed are safe for patient
-understand purpose, dosage, route of administration, SE
-contact HCP for clarification if prescription is difficult to read, missing required information, contains prohibited/unfamiliar abbreviations
Nurse's Role In Medication Administration
-assesses patient's ability to self-administer
-determines medication timing
-administers medications correctly
-closely monitors effects
-provides patient teaching
-doesn't delegate medication administration to AP
Medication Administration: Nursing Assessment
Through the patient's eyes
-consider pt's preferences & values
-assess patient experiences
History
-allergies
-medication
-diet history
-perceptual or coordination problems
Miscellaneous
-patient's current condition
-patient's attitude about medication use
-factors affecting adherence to medication therapy
-patient's learning needs
Medication Administration: Nursing Diagnosis
-impaired health maintenance
-lack of knowledge
-nonadherence (medication regimen)
-adverse medication interaction
-complex medication regimen (polypharmacy)
Medication Administration: Nursing Planning
-organize care activities
-goals and outcomes
-setting priorities
-teamwork and collaboration
Medication Administration: Nursing Implementation
-health promotion
Patient and family caregiver teaching
-acute care
receiving, transcribing, communicating medication orders
accurate dose calculation and measurement
-special considerations
infants & children
older adults
Medication Administration: Nursing Evaluation
-partner w/your patients
ensure patients understand and can safely administer their medications
-evaluate outcomes
use knowledge of desired effect and common side effects of each medication to compare expected outcomes w/actual findings
more sensitive, potent
Lifespan Considerations in Medication Administration: Aging
Drug-receptor Interaction: brain receptors become ____, making psychoactive drugs very ____.
1. shrinks
2. decline
3. prolonging
Lifespan Considerations in Medication Administration: Aging
Metabolism:
-Liver mass (1)
-hepatic blood flow and enzyme activity (2).
-metabolism drops to one-half the rate of young adults
-enzymes lose ability to process some drugs, thus (3) drug half-life
1. slow
2. capacity
Lifespan Considerations in Medication Administration: Aging
Absorption: Gastric emptying rate and GI motility (1). Absorption (2) of cells and active transport mechanism decline.
1. less stable
Lifespan Considerations in Medication Administration: Aging
Circulation:
-Vascular nerve control is less (1).
e.g. antihypertensives drop BP too low
1. decline
2. lengthen
3. longer
Lifespan Considerations in Medication Administration: Aging
Excretion
-In kidneys, renal blood flow, GFR, renal tubular secretion and reabsorption, and number of functional nephrons (1).
-blood flow and waste removal slow
-age-related changes (2) half-life for renally excreted drugs
e.g. antidiabetic drugs stay in the body (3)
1. declines
2. water-soluble
3. plasma protein
4. free drug
Lifespan Considerations in Medication Administration: Aging
Distribution
-Lean body mass falls; adipose stores increase
-TBW (1), raising the concentration of (2) drugs, like digoxin
-(3) diminishes, reducing sites available for protein-bound drugs and raising blood levels of (4)
oral administration
-Easiest and most desirable route.
-Food sometimes affects absorption.
-time or delayed-release, enteric-coated medications: do not crush
Consider
-NPO status
-inability to swallow safely
-persisten N/V
-gastric suction
-decreased LOC
sublingual and buccal
rapid absorption of medications because they bypass the digestive system and also allow medications to enter the bloodstream without being partially metabolized by the liver
enteral tube administration
special precautions when administering medications to patients w/enteral or small-bore feeding tubes
-follow tubing connection standards
-verify tube is compatible w/medication absorption
-use liquid medications when possible
-flush b/w medications
1. cannot
GI Tube
-many, but not all, PO medications can be given through GI tube
-liquid form of a medication should be given whenever available
-enteric-coated, time-release, sublingual, buccal, and other medications w/special coatings (1) be administered through GI tube
-any medication given through GI tube requires a prescription specifically stating GI route
A. clean
B. abdomen, hips, and thighs
C. breast/waistline
D. heat
Estrogen Patch
1. Using a soft-tip or felt-tip marker, write the date, time, and initials on the new patch.
2. Put on (A) gloves.
3. Select a clean, dry site away from previous site and free of hair. Avoid site where skin is oily, burned, cut or irritated.
4. Estrogen patches are commonly applied to the flat areas of the (B).
They should never be applied on/near the (C).
5. Explain that the patient shouldn't apply (D) or ointment over patch.
chest, back, abdomen, anterior thigh
Name four sites to apply nitroglycerin ointment.
Don't apply on hairy surfaces or over scar tissue; don't massage ointment into skin.
Name two considerations for nitroglycerin ointment.
Considerations for Oral Medications
-medications that require a pre-assessment (BP, HR) should be placed in a separate medication cup
-give each crushed medication separately
-administer tablets or capsules w/patient in sitting or side-lying position
-if liquid medication is less than 10 mL --> oral syringe
-give sublingual and buccal medications last
enteric-coated, long-acting, sustained-release, sublingual
Which medications shouldn't you crush?
1. existing
2. disposable, clean gloves
3. label
4. location
5. removal
Topical Administration
-When applying a transdermal patch, ask the patient whether he or she has an (1) patch
-Wear (2) when removing and applying transdermal patches
-If the dressing or patch is difficult to see (e.g., clear), apply a noticeable (3) to the patch
-Document patch or medication (4) on the MAR
-Document patch or medication (5) on the MAR
lotions, creams, oils, ointments, patches, powders, and aerosol sprays
nasal instillation
Methods
-Spray
-Drops
-Nasal Tampons (severe nosebleeds)
Decongestant spray or drops most common
-Caution patients to avoid the rebound effect
-Serious systemic effects also develop if excess decongestant solution is swallowed, especially in children
1. cornea
2. eye/eyelid
3. affected
4. conjunctival sac
Eye Instillation
Administration involves placing the medication in the patient’s eye using correct technique for the medication form
Instillation: eye drops, ointments, irrigations, and disks
-Avoid the cornea
-Avoid touching (2) with droppers or tubes
-Use only on the (3) eye
-Never share eye medications
Intraocular instillation
-Disk resembles a contact lens
-Teach patients how to insert and remove the disk from (4)
1. room temperature
2. sterile
3. drainage
4. occlude
5. down & back
6. up & back
7. side-lying position
8. cerumen
Ear Instillation
Eardrops: topical preparations, usually in the form of drops
-Instill eardrops at (1)
-Use (2) solutions.
-Check with the provider if patient has ear (3)
-Never (4) the ear canal.
-Children <3 years: pull pinna (5)
-Adults: pull pinna (6)
-If medication is ordered for both ears, ask patient to stay in (7) position for a few minutes.
Irrigation
Remove (8) that cannot be removed with wax softeners
vaginal installation
Suppositories, foam, jellies, or cream; stay in position for 10 mins
rectal instillation
-Thinner and more bullet-shaped than vaginal suppositories
-Rounded end prevents anal trauma during insertion
-Contain medications that exert local effects
-A small cleansing enema may be required before inserting a suppository (liquid)
-Left side laying sims position with right leg flexed or dorsal recumbent position. Stay in position for 5 minutes
inhalation administration
includes small volume nebulizer, pressurized metered-dose inhalers, breath-actuated metered-dose inhalers, and dry powder inhalers
pressurized metered-dose inhalers (pMDIs)
-Require hand strength and hand-breath coordination
-May be used with a spacer
Breath-actuated metered-dose inhalers (BAIs)
Release depends on strength of patient's breath on inspiration
dry powder inhalers (DPIs)
-Activated by patient's breath
-Deliver more medication to the lungs