[mtap 2] systemic mycoses

dimorphic fungi

systemic mycoses are usually caused by

mold form

systemic mycoses causative agents are usually in this form

Blastomyces dermatitidis

Coccidioides immitis

Paraccoccidioides brasiliensis

Histoplasma capsulatum

causative mold forms of systemic mycoses are the following:

Blastomyces dermatitidis

Causative agent of Blastomycosis

• Gilchrist’s disease

• North American Blastomycosis

• Chicago disease

Other names of Blastomycosis include:

River Valley in South East, Midwest, and Southern US

Blastomycosis is endemic in:

lollipop conidia

In room temperature, the mold form of Blastomycosis includes:

broad-based budding

In body temperature, the yeast form of Blastomycosis includes:

Specific A band

For the laboratory diagnosis of Blastomycosis using the EXOANTIGEN TEST, what in particular are we looking for in a positive test result?

WI-1

Gene present in Blastomycosis, used for its diagnosis:

• Chronic, Suppurative Granulomatous Skin Disease

• Pulmonary Disease

  • Affects bone, skin, prostate

What are the clinical manifestations of Blastomycosis?

• South American blastomycosis

• Para

• Paracocci

Paracoccidioidomycosis is also known as:

Paracoccidioides brasiliensis

The causative agent of Paracoccidioidomycosis is:

Chlamydoconidia

At room temperature, the mold form of Paracoccidioides brasiliensis appears to have:

“Mariner’s Wheel” or Mickey Mouse’s Cap

At body temp, the yeast form of Paracoccidioides brasiliensis appears to have:

Bands 1,2,3

For the laboratory diagnosis of Paracoccidioidomycosis using the EXOANTIGEN TEST, what in particular are we looking for in a positive test result?

gp43

Gene present in Paracoccidioidomycosis, used for its diagnosis:

• TB-like pulmonary infection

• Suppurative and Granulomatous ulcers of mucosal areas

Clinical manifestation of Paracoccidioidomycosis:

• San Joaquin Valley fever

• desert fever

• desert rheumatism

• cocci

• the bumps

other names for Coccidioidomycosis

Coccidioides immitis

Coccidioidomycosis causative agent

Coccidioides immitis

This is the most virulent of all the human mycotic infections

arthroconidia

At RT, the mold form of Coccidioides immitis shows

spherules

At BT, Coccidioides immitis does not possess a yeast form, but rather shows

• California

• Mexico

• South and Central America

Coccidioidomycosis is rampant in these regions in the Americas:

Coccidioides posadasii

This is another species that causes Coccidioidomycosis, but outside the Americas:

BSL III

Biosafety level for C. immitis, B. dermatitidis, and H. capsulatum is:

• Darling’s Disease

• Reticuloendothelial Cytomycosis

• Cave disease

• Spelunker disease

Other names for Histoplasmosis include:

Histoplasma capsulatum

The etiologic agent of Histoplasmosis is:

Histoplasma duboisii

Another agent of Histoplasmosis, particularly called African Histoplasmosis, is called:

• Central Mississippi

• Missouri

• Ohio

• River Valleys

• Apalacchian Mountains

Histoplasmosis is endemic in these areas:

Bats

Starlings

The reservoir host for Histoplasmosis are the fecal matters of which animals:

Intracellular mycotic infection of the reticuloendothelial system

Histoplasmosis is actually a:

tuberculate macroconidia

Pyriform macroconidia

At RT, the mold form of Histoplasma capsulatum shows:

Small budding east cells within macrophages

At BT, the yeast form of H. capsulatum shows:

the amastigote stage of Leishmania donovani

The yeast form of H. capsulatum can be mistaken for

H and M

The exoantigen present with Histoplasmosis are

Giemsa

Periodic Acid Schiff

Gomori Metalamine Silver

Stains used for the visual examination of Histoplasmosis are:

CHO Ag

In urine, this antigen is used to diagnose Histoplasmosis