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What part of the brain is responsible for voluntary motor function?
Frontal lobe
What part of the brain is responsible for equilibrium, coordination, and proprioception?
Cerebellum
What changes occur to the musculoskeletal system with old age?
Thinning vertebral disks, shortening spinal column, kyphosis, decreased bone density
What happens to the cardiovascular system during immobility? (3 changes)
orthostatic hypotension, increased cardiac workload, increased thrombus formation
Nursing interventions for immobility
Passive and active ROM, frequent repositioning, encourage oral fluids, TEDs, SCDs
A nurse is assessing for complications of immobility. Which of the findings should the nurse expect? Select all that apply
Diarrhea
Pressure ulcers
Contractures of extremities
Crackles in the lungs
Polyuria
Pressure ulcers, contractures of extremities, crackles in the lungs
What effects happen to the respiratory system during immobility? (3 changes)
Decreased ventilation, decreased V:Q ratio, stasis of secretions
What part of the body is most sensitive to lack of oxygen?
Brain
Effects of immobility on GI system
decreased peristalsis, constipation, anorexia
What is contractures and when do they form?
Shortening of muscle fibers and begins after 8 hours of immobility
Effects of immobility on integumentary system
Decreased tissue perfusion, pressure ulcers
What does the Braden scale assess?
Risk for pressure injury development. Lower the score the increased risk for injury. Factors include sensory perception, moisture, activity, mobility, nutrition, and friction/shear.
Effects of immobility on urinary system
overflow incontinence, urine stasis, renal calculi, infection
What are the clinical manifestations of inflammation?
Redness, swelling, heat, pain, impaired function
A nurse is assessing a client for a suspected anaphylactic reaction following a CT scan with contrast dye. For which of the following client findings should the nurse intervene?
Urticaria
Stridor
Vomiting
Hypotension
Stridor
What cells are the first to arrive to an inflammatory site?
Neutrophils
Where does histamine come from and what does it do?
Stored and released from mast cells. Causes early vasodilation and increases permeability. Chemically attracts eosinophils
What does bradykinin do?
Dilation of vessels, increases vascular permeability, stimulates histamine release
What does leukotrienes do?
Helps with inflammation and increases mucous. Chemically attracts neutrophils and macrophages
What do mast cells?
increase vasodilation and permeability
What are the stages of inflammation?
Stage 1- vascular and cellular response
Vascular- initial vasoconstriction at site followed by vasodilation. Increased capillary permeability
Cellular- movement of leukocytes to cite. Formation of exudate
Stage 2- Exudate production
Stage 3- Reparative stage
What are the types of exudate?
Serous- watery
serosanguinous- pinky
Purulent- puss-like
Hemorrhagic- bloody
What is regeneration?
Tissue replaced from parenchyma (labile tissues)
What is repair?
Process of laying down connective tissue to restore strength and structure of tissues
What is primary healing?
Filled with blood clot, reepithelization and revascularization, and collagen formation
What is secondary healing?
Seen in wounds with unapproximated edges. Heals from the bottom up
What is dehiscence?
Wound pulls apart at suture line
What is evisceration?
Wound opens and organs expel
What is a fistula?
Abnormal passageway
What increase neutrophils a sign of?
Bacterial infection, ischemia
What are increased lymphocytes a sign of?
viral infection
What are increased eosinophils a sign of?
Allergic reaction or parasitic infection
What is SIRS criteria?
Requires 2+ of the following:
Temp >38 or <36
Heart rate >90
RR >20 breaths per minute
WBC >12,000 or <4,000
>10% bands
The nurse is evaluating teaching provided to a client with chronic inflammation. Which client statement indicates to the nurse that teaching has been successful?
A. “I limit doing things that aggravate the pain.”
B. “I refrain from physical activity.”
C. “I think it would be best if I got a wheelchair and didn’t walk again.”
D. “I ignore the pain until I can’t stand it anymore.”
A
What is C-reactive protein?
Elevated in response to inflammatory process
<1= low risk for developing CV disease
1-3= average risk of developing CV disease
>3= high risk of developing CV disease
What is erythrocyte sedimentation rate (ESR)?
Lab to detect non-specific inflammation
Higher number indicated inflammation
Normal in 0-15 (men) or 0-20 (women)
The nurse conducts screening for inflammatory diseases with clients of a community health clinic. Which test should the nurse perform?
A. MRI
B. Xray
C. Urine Test
D. Skin Test
D
What is the POLICE acronym for inflammation?
protection and optimal loading, ice, compress, elevate
What is the treatment of anaphylaxis?
Epinephrine. Emergency tracheotomy if severe
What are sources of biogenic stress?
Amphetamines, caffeine
What are the stages of general adaptive syndrome?
Alarm, resistance, exhaustion
What happens during metabolic stress response?
Ebb phase- 24 hours. Metabolic rate is unchanged or decreased.
Flow phase- hypermetabolism with increased O2 and calorie demands
What are the manifestations of Addison’s disease?
Fatigue, weight loss, low BP, low glucose, low Na, High K, high Ca
What are the manifestations of Cushing’s disease?
Obesity, round face, hirsutism, fragile skin, HTN, DM, Low K
What are the functions of epinephrine?
Increases HR, facilitates blood flow to muscles and brain, relaxes smooth muscle, assists with conversion of glycogen to glucose
What are the functions of norepinephrine?
Vasoconstriction, maintaining BP and increasing it in acute stress
What is the most severe and incapacitating form of stress?
PTSD
DSM criteria for schizophrenia
Positive symptoms, at least one per week for one month, progression, condition is distressing/disabling, symptoms cannot be explained by other DSM-5 diagnosis
Lifespan groupings for schizophrenia
Early onset- before 17 years old
Late onset- after 40
Very late onset- after 60
What happens to the brain during schizophrenia?
Increase dopamine in basal ganglia, decreased dopamine in prefrontal cortex, increase in ventricle size, decrease in size of thalamus, prefrontal cortex, and hippocampus
What is an example of a grandiose delusion?
Homeless person believing they are a millionaire
What is an example of a somatic delusion?
Believing their sinuses are filled with worms
What alogia?
Poverty of speech and thoughts
What is avolition?
Lack of motivation
What are the phases of schizophrenia?
Premorbid- nonspecific emotional, cognitive, or motor delays
Prodromal- general symptoms appear
Acute- Positive symptoms develop
Stabilization- occurs 6-18 months after acute phase. Does not have acute phase symptoms
Maintenance- patient returns to functional status
What are the side effects of first generation anti-psychotics?
EPS, tardive dyskinesia, anticholinergic side effects, hyperprolactinemia
Side effects of second generation antipsychotics
Neutropenia, agranulocytosis, weight gain, EPS, NMS
What is EPS?
Abnormal muscle movements caused from too much D2 in nigrostriatal pathway.
What is acute dystonia and how to do we treat it?
Sustained muscle contraction
Treated with Cogentin or benztropine
How do we treat pseudo parkinsonism?
Cogentin or aretane
What is akathisia and how do we treat it?
Inability to sit still
Treat beta blockers (propranolol), parkinson meds, ativan, alprazolam
What is echolalia?
Client repeats words spoken to them