Pancreatitis (Johnny Poo)

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6 Terms

1
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What happens to blood glucose during acute pancreatitis?

  • Temporary hyperglycemia due to stress hormones (cortisol, adrenaline) ↑ glucose & ↓ insulin sensitivity

  • May also be due to temporary beta cell dysfunction

2
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How is hyperglycemia managed in acute pancreatitis?

  • Insulin as needed

  • Not considered diabetes unless hyperglycemia persists after recovery

3
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What type of diabetes can chronic pancreatitis lead to?

Type 3c Diabetes Mellitus (T3cDM) → due to pancreatic disease, not autoimmune or insulin resistance

4
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What is the mechanism of diabetes in chronic pancreatitis?

  • Progressive, irreversible damage to endocrine pancreas → beta cell loss (↓ insulin) & alpha cell loss (↓ glucagon)

  • Often accompanied by exocrine insufficiency (malabsorption, malnutrition)

5
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What percentage of chronic pancreatitis patients may develop T3cDM?

Up to 80%

6
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Is diabetes from chronic pancreatitis the same as type 1?

  • No. Type 1 = autoimmune destruction

  • Chronic pancreatitis = Type 3c diabetes (secondary to pancreatic damage)

  • Often misdiagnosed as type 2 due to similar presentation