Complete Blood Count with Differential

What does RBC count lab test measure?

RBC count measures the total amount of RBC in 1mm3 of peripheral venous blood

What do RBC do in the body?

They contain hemoglobin, which allows the transport of oxygen and carbon dioxide

What is the normal value for RBC Count?

Adults/Elderly: 4.7-6.1% per 1mm3 of blood

What does hematocrit count lab test measure?

The percentage of total blood volume made up by RBC

What are the normal values for hematocrit?

Adult Males: 42-52%

Adult Females: 37-47%

What does the hemoglobin lab test measure?

The total amount of hemoglobin in the peripheral blood

What does hemoglobin do in the body?

Transports O2 to the cells and CO2 to the lungs. It determines O2 carrying capacity.

What are the normal values for hemoglobin?

Adult males: 14-18 g/dL

Adult females: 12-16 g/dL

What does the WBC count lab test measure?

The total amount of WBC present in a cubic mm of peripheral venous blood

What do WBCs do in the body?

They fight infection and react against foreign bodies and tissues

What are the normal values for WBC?

Adults/Children>2: 5,000-10,000

What do the WBC differential lab tests measure?

The total number of a certain WBC present within the same specimen.

What do neutrophils do in the body?

Phagocytosis: the killing and digestion of bacterial microbes

What are the normal values for neutrophils?

%: 55-70%

Absolute: 2,500-8,000/mm3

What do lymphocytes do for the body?

Fight chronic bacterial infections and acute viral infections.

• T cells (killer/suppressor/t4 cells) are involved with cellular-type immunity

• B cells are involved with humoral immunity (anitbody production)

What are the normal values for lymphocytes?

%: 20-40%

Absolute: 1000-4000/mm3

What do monocytes do for the body?

• Remove necrotic debris and microbes from the blood using phagocytosis

• Produce interferon

• Also respond more rapidly than neutrophils and stay in circulation longer

What are the normal values for monocytes?

%: 2-8%

Absolute: 100-700/mm3

What do eosinophils do in the body?

Involved w/allergic reactions, respond to parasitic infections

• capable of antigen-antibody phagocytosis + infiltrate involved tissues to further inflammatory reaction

What are the normal values for eosinophils?

%: 1-4%

Absolute: 50-500/mm3

What do basophils do in the body?

Involved in allergic reactions and respond to parasitic infections

What are the normal values for basophils?

%: 0.5-1%

Absolute: 25-200/mm3

What do platelets do in the body?

Aid in hemostasis via platelet aggregation and initiation of the coagulation factor cascade

what are the normal values for platelets?

Adults/Elderly: 150-500,000/mm3

Under what platelet value may spontaneous bleeding occur?

20,000 platelets/mm3

Why are T-cells called such?

They mature in the thymus

Why are B-cells called such?

They mature in the bone marrow

What does a shift to the left refer to?

The increased presences of bands (baby neutrophils) which indicates acute infections/trauma