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Mitral Annular Calcification (MAC)
Annulus of MV degenerates
Results in echogenic, shelf-like, irregular lumpy deposits
Exacerbates MV stenosis & regurgitation
Causes of Mitral Annular Calcification
Advancing age
Atherosclerosis
Hypertension
Hypercholesterolemia
Diabetes
Chronic kidney disease
MV prolapse
Post Radiation treatments
Congenital metabolic disorders
Most likely valve to prolapse
MV
Mild Mitral Annular Calcification
Focal areas of increased echogenicity around MV annulus

Moderate Mitral Annular Calcification
1/3 to 1/2 of the MV annulus has increased echogenicity

Severe Mitral Annular Calcification
More than ½ of the MV annulus has increased echogenicity

Causes of MV Stenosis
Rheumatic Heart Disease
Calcium deposits
Radiation therapy
Signs & Symptoms of MV Stenosis
Difficulty breathing
Hemoptysis - coughing blood
Hoarseness
Syncope
Peripheral edema
Palpitations
Murmur
CVA/TIA
ABNL EKG
2D Features of MV Stenosis
Hockey stick appearance of anterior leaflet
Fibrosis & shortening of chordae
"Smoke" in chambers
LA enlargement
LV enlargement & hypertrophy
RV enlargement & hypertrophy

M-Mode Features of MV Stenosis
Decreased E-F slope
Decreased A wave
Reduced D-E excursion

Doppler Features of MV Stenosis
Increased A wave
Increased pressure half-time
Spectral broadening

Causes of MV Regurgitation
Mitral annular calcification
Marfan's Syndrome
Myxomatous MV disease
Hypertrophic obstructive cardiomyopathy
Signs & Symptoms of MV Regurgitation
Murmur
Difficulty breathing
Pulmonary HTN
Arrhythmia
ABNL EKG
2D Features of MV Regurgitation
LA enlargment
LV volume overload
IAS bowing

M-Mode Features of MV Regurgitation
Incomplete closure of MV in systole
Increased E-F slope
Early AV closure or mid-systolic notching
Possible prolapse

Doppler Features of MV Regurgitation
Retrograde flow into LA during systole
Parabolic flow profile below baseline
Spectral broadening
Decreased S & D waves of pulmonary V. inflow

MV Prolapse is almost always associated with...
MV regurgitation
Causes of MV Prolapse
Unknown
Connective tissue disorders - Marfan's
Heredity
Drugs
Rheumatic fever
Graves' disease
MV Prolapse is best viewed in...
PLAX
Apical 4 chamber
Clinical Findings of MV Prolapse
Mid-systolic click
Cardiomegaly
Murmur
Normal EKG
Signs & Symptoms of MV Prolapse
Asymptomatic
Chest pain/discomfort
Palpitations
Lightheadedness/syncope
Shortness of breath
Headaches
Cough
M-Mode Features of MV Prolapse
Posterior displacement of leaflet(s)
Posterior hammocking of C-D segment
2D Features of MV Prolapse
Arching of leaflet(s) into LA
Scalloped appearance of leaflets
Doppler Features of MV Prolapse
Mitral regurgitation
Posterior jet - if anterior leaflet prolapses
Anterior jet - if posterior leaflet prolapses
Maneuvers to enhance diagnostic accuracy of MV Prolapse
Patient supine, sitting, standing
Valsalva maneuver
Amyl nitrate
Sequelae of MV Prolapse
Risk for infective endocarditis
Ruptured chordae
Embolis
Sudden death
Treatments for MV Prolapse
Medications to prevent infection & regulate heart rhythm
Blood thinners
Diuretics
MV repair or replacement
Causes of LVOT Obstructions
Hypertrophy of IVS
Features of LVOT Obstruction
Narrowed outlet
Turbulence & increased velocities
LV hypertrophy, enlargement, and eventual failure
Can be subvalvular, valvular, or supravalvular
Causes of AV Stenosis
Rheumatic Heart Disease
Obstruction
Endocarditis/vegetations
Prosthetic valve dysfunction
Bicuspid or unicuspid valve
AO stenosis/coarctation
Age related degeneration
Signs & Symptoms of AV Stenosis
Angina
Heart attack/stoke
Congestive heart failure
Murmur/arrythmia
Syncope/dizziness
Difficulty breathing
Pulmonary edema
Decreased cardiac output
Sudden death
2D Features of AV Stenosis
Thickened cusps with restricted motion
Doming of cusps
Reduced valvular orifice
Possible fusion of cusps
LA enlargement
LV enlargement & hypertrophy
Ascending AO dilation

M-Mode Features of AV Stenosis
Decreased cusp separation

Doppler Features of AV Stenosis
Increased velocities
Spectral broadening

Causes of AV Regurgitation
Chamber Enlargement
Trauma
Intracardiac devices
Endocarditis/vegetations
Masses
Valve Prolapse
Rheumatic heart disease
Prosthetic valve dysfunction
Age related degeneration
Bicuspid AV
Ascending Aortic dilatation
Aortic dissection
Signs & Symptoms of AV Regurgitation
Angina
Difficulty breathing
Excessive sweating
Pounding pulse
Murmur
Syncope/dizziness
2D Features of AV Regurgitation
LV enlargement & hypertrophy
Decreased LV function
Thickened, non-coapting leaflets with abnormal motion
Annular dilatation
M-Mode Features of AV Regurgitation
Non-coaptation of cusps in diastole
Decreased D-E excursion
Prominent A wave
Doppler Features of AV Regurgitation
Retrograde flow into LV during diastole
Trapezoidal flow profile above baseline
Spectral broadening

AV Prolapse
Abnormal motion of cusps
If present, there should be AI
Not common here

AV Masses
Endocarditis - vegetations
Masses from LV
