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Two drugs for Cold?
Pseudoephedrine and phenylephrine
tell me about the oral version of the two drugs
Pseudoephedrine orally works but the phenylephrine orally doesn’t work. However the internasal spray version of it is effective.
What are the intranasal spray and tell me which are long acting and which are short acting?
They Oxymetazoline, Nephazoline, Phenylephrine, Tetrahydrozoline.
The only one that is long acting is the Oxymetazoline and everything else is short acting.
What are the intranasal inhaler for COLD
They are all short acting, Propylhexedrine and levamfetamine
What do you cause when you use internasal decongestant too frequently?
It will cause Rhinitis Medicamentosa which is rebound nasal congestion.
What are the adverse effects of the oral decongestant?
Issues with cardiovascular and cns stimulant : high BP, insomina, rapid heart beating.
For allergies, tell me the difference between the NAR and AR
NAR is for non allergic symptoms
AR is for allergic symptoms
What is the goal of treating allergic patients?
We want to treat the symptoms or either provide them with relief that makes them more functional with their daily task.
*we can also suggest them to avoid allergen area or exposure
What are the pharmacological therapy for the allergy?
we suggest first line medication: like intranasal corticosteroid and intranasal antihistamine(targeting the MASK cell)
What are the drugs for intranasal corticosteroid?
Fluticasone propionate: NAR, PAR, AR
Fluticasone furoate, Mometasone, Triamcinolone acetonide, budesonide: PAR and AR only
What are some first generation intranasal antihistamine?
Diphenhydramine and chlorpheniramine. (contain hydroxyzine)
What are 2 generation internasal antihistamine?
cetirizine and levocetirizine
loratadine and fexofenadine
Types of cough treatment drug.
antitussive for dry cough
protussive for wet cough
what is a pharmacology therapy OTC drug for cough
dextromethorphan: it’s a nonselective/first generation antihistamine oral drug for dry cough so it’s a antitussive drug
Guaifenesin: it’s a expectorant which loosens the mucus and it’s for wet cough.
Tell me the difference between two types of Dextromethorphan with agents?
Induced version = increase metabolism = lower efficacy
inhibited version = decrease metabolsim= high effeicacy
what drug is for cold sore and what drug class?
It’s the only OTC, Ducosanol, it’s a topical antival agent