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Flashcards for key vocabulary related to the urinary system.
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Kidneys
Filter blood and form urine.
Ureters
Transport urine from kidneys to urinary bladder.
Urinary bladder
Collects and stores urine.
Urethra
Conveys urine from urinary bladder to outside of body.
Kidney Functions
Filter blood and remove metabolic waste from the body, maintenance of fluid and electrolyte balance, maintenance of acid-base balance, maintenance of blood pressure, regulation of erythropoiesis, performing other metabolic functions
Location of the kidneys
Lie on both sides of vertebral column, in a depression on the posterior abdominal wall; positioned retroperitoneally (behind the parietal peritoneum).
Renal Sinus
Hollow chamber in medial depression of the kidney
Renal cortex
Outer region of kidney
Renal medulla
Inner region of kidney; composed of renal pyramids
Renal columns
Extensions of cortex that dip into medulla
Hilum
Entrance to renal sinus
Renal pelvis
Funnel-shaped sac; superior end of ureter
Major calyces
Large tubes that merge to form renal pelvis
Minor calyces
Small tubes that merge to form major calyces
Renal capsule
Fibrous capsule around kidney
Nephrons
Functional units of kidney, each of which is a site of urine production
Renal artery
Branches off abdominal aorta, enters kidney through hilum - Kidneys receive around 25% of total cardiac output.
Segmental arteries
Branch off renal artery
Interlobar arteries
Branch off segmental arteries, flow between renal pyramids
Arcuate (arciform) arteries
Branch off interlobar arteries, arch around renal pyramids
Cortical radiate (interlobular) arteries
Branch off arcuate arteries
Renal corpuscle
Filtering unit of the kidney located in the renal cortex.
Glomerulus
Fenestrated capillary cluster that filters blood to begin urine formation.
Glomerular (Bowman’s) capsule
Receives filtrate from glomerulus
Renal tubule
Extends from glomerular capsule to collecting duct
Filtrate Pathway
From Glomerular Capsule → Proximal (convoluted) tubule → Nephron loop (loop of Henle, composed of a descending and an ascending limb) → Distal (convoluted) tubule
Glomerular filtration
Performs glomerular filtration using specialized glomerular capillaries.
Tubular reabsorption
Transfer of filtered substances from renal tubules to peritubular capillaries.
Tubular secretion
Transfer of certain substances from peritubular capillaries to renal tubules.
Podocytes
Modified epithelial cells that make up the inner visceral later of the glomerular capsule. They wrap around glomerular capillaries with foot-like processes called pedicles that form filtration slits.
Fenestrae
Tiny openings in the walls of glomerular capillaries that make them more permeable to small molecules.
Glomerular filtration rate (GFR)
The amount of filtrate produced per minute by both kidneys.
Renal autoregulation
The ability of the nephrons to adjust their own blood flow and GFR without external (nervous or hormonal) control.
Renin-angiotensin-aldosterone system
A hormone-like system that controls GFR.
Macula densa cells
Cells of the juxtaglomerular apparatus (JGA) that detect decreases in blood pressure and levels of Na+, K+, and Cl-.
Nephritis
Inflammation of the kidney.
Renal plasma threshold
Concentration of a substance in plasma at which it begins to be excreted in the urine
ADH (antidiuretic hormone, or vasopressin)
Stimulates the distal convoluted tubules and collecting ducts to insert specialized water channels called aquaporins.
Countercurrent mechanism
Keeps the interstitial fluid in the medulla hypertonic, which favors reabsorption.
Urea
A product of amino acid catabolism
Uric acid
A product of nucleic acid metabolism
Renal clearance test
Measures the rate at which a chemical is removed from the plasma by the kidney; Used to determine GFR
Ureters
Tubular organs, about 25 cm long, which transports urine from kidney to urinary bladder
Urinary bladder
Hollow, distensible, muscular organ in pelvic cavity that stores urine and sends it into the urethra.
Micturition (urination)
Expulsion of urine from the urinary bladder.