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Alcohol
Memory loss, oxygen damage, impaired actions
Heroin
Flush of euphoric relief from pain
Caffeine
Increased alertness and wakefulness
Meth
euphoria, alertness, and energy
Cocaine
Rush of euphoria and confidence and energy and negative aftereffects of cardiovascular stress and suspiciousness
Nicotine
Arousal and relaxation and negative aftereffect of heart disease
Ecstasy (MDMA)
Emotional elevation and disinhibition
LSD
Visual trip
Marijuana
Enhanced sensation, relief of pain, distortion of time, and relaxation, and negative aftereffect of lung damage from smoke