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plasma membrane
composed of phospholipid bilayer with embedded proteins and cholesterol molecules
fluid-mosaic model (of the plasma membrane)
describes the fluidity of the membrane and its components. Phospholipids and embedded proteins move freely around one another, forming a “fluid-mosaic”
plasma membrane functions
separates the internal cytoplasm frmo the external environment of the cell
controls the movement of substances in and out of the cell
allows cells to communicate with one another and interact with their external environment
Plama membrane components
liquid component referred to as a phospholipid bilayer
hydrophilic polar heads of the phospholipid molecules line the internal (cytoplasmic) and external (extracellular) surface of the membrane
hydrophobic fatty-acid tails of the phospholipids are sandwiched in between
protein molecules
float around like icebergs in a sea of phsopholipids
peripheral proteins
found on the inner membrane surface
integral proteins
partially or wholly embedded (transmembrane) in the membrane, amphipathic - have both hydrophobic and hydrophilic regions, portion embedded within the phospholipid is hydrophobic, while the portion of the protein exposed to the interior or exterior of the cell is hydrophilic
cholesterol
embedded in the phospholipid bilyaer controls the fluidity of the membrane (makes the membrane more or less fluid depending on the temperature)
At warm temperatures, retrains movement of phospholipids
At cool temperatures, it maintains fluidity by preventing tight packing
glycoproteins
proteins with attached carbohydrate chains
glycolipids
phospholipids with attached carbohydrate chains (golgi adds on chains after the protiens and lipids are produced by the ER)
Channel proteins
allow passage of specific ions or molecules through membrane via a channel in the protein (tunnel)
carrier proteins
combine with the molecule or ion to be transported and assist its passage through membrane (opens and closes)
cell recognition proteins
eg. glycoproteins, help cells identify one another
receptor proteins
shaped in such a way that specific molecules bind to it, allow a cell to respond to signals from other cells
enzymatic proteins
catalyze specific reactions
junction proteins
attach adjacent cells so that a tissue can fulfill a function
Permeability of plasma membrane
small, hydrophobic (nonpolar) molecules (eg. CO2, O2, and glycerol) freely cross the membrane by passing through the phospholipid bilayer
Polar or charged substances (eg. sugars and ions) do not cross the membrane and rely on transport proteins
Cell size
smaller cells have a large SA/V ratio = more efficiency of transporting material in and out of the cell
passive transport
movement of substances across the cell membrane without energy
both sides get closer to equilibrium (same concentration)
high to low concentration
diffusion, osmosis, and facilitated transport
Diffusion
net movement of molecules down a concentration gradient
molecules move both ways along the gradient, but net movement is from high to low concentration
NET movement stops when the molecules reach a dynamic equilibrium
molecules still move both ways, but at equal rates
solute concentration is uniform - no concentration gradient
Osmosis