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Review of all articles relevant to a topic involves
a systematic review
For Systematic Review (SR), criteria for inclusion established
prospectively
Systematic Review (SR) quality rating of evidence must be relevant to
specific clinical question and looked at before starting
Systematic Review (SR) have ______ methods
eplicit
Systematic Review (SR) goal is to minimize
bias
Systematic Review (SR) may or may not include a
meta-analysis
________ is a quantitative analysis that is focused on contrasting and combining results from different studies in the hope of identifying patterns among study results, sources of disagreement among those results, or other interesting relationships that may come to light in the context of multiple studies
Meta-analysis
Meta-analysis may or may not be part of a
systematic review
Meta-analysis results can be __________ if not part of systematic review
misleading
Conceptually, a meta-analysis uses a _______ approach to combine the results from multiple studies
statistical
Meta analysis advantages an therefore be interpreted as follows:
– Results can be generalized to a larger population, – The precision and accuracy of estimates can be improved as more data is used. This, in turn, may increase the statistical power to detect an effect.
34-39
Randomized clinical trial involves _____ assignment of pts
random
In a randomized clinical trial there is a(n) __________ manipulation and ______ measurement of variables
prospective; precise
Randomized clincial trials have
strong internal validity
Randomized Clinical Trial provided evidence of treatment
efficacy
Beneficial therapeutic effect under ideal conditions
Non-randomized assignment of subjects to groups (experimental or control)
Quasi-Experimental
______ can be very difficult, impractical, or even unethical for evaluation of some medical treatment
RCTs
A method of group decision-making and forecasting that involves successively collating the judgments of experts
– Practice recommendations – Search categories – PT education
Delphi/Modified Delphi Technique
Epidemiology is the study of
a soiety’s collective health
A group of people with a common experience over a defined period of time
Cohort (common in medical research)
A cohort study include all of the following except
Small number of subjects and short duration required