ALL TOPICS QUIZ PTCB

Which of the following medication’s increases the effect of potassium chloride?: Spironolactone, furosemide, torsemide, bumetanide

Spironolactone - Spironolactone is a potassium sparing diuretic while potassium chloride is a potassium supplement that is indicated for hypokalemia. Co-administration of spironolactone and potassium chloride will increase serum potassium, putting patients at risk for hyperkalemia.

What is the MOA of ACE inhibitors?

They work by inhibiting the conversion of angiotensin 1 into angiotensin 2. ACE (angiotensin-converting enzyme) inhibitors prevent the conversion of angiotensin 1 to angiotensin 2, which causes vasoconstriction and high blood pressure.

You are billing an insurance company for the following medication: 60 tabs with an AWP of $590 for 1,000 tablets with a 6% markdown and a $5 dispensing fee. How much should be billed to the insurance company?

$38.28 - (AWP) + (markup or -markdown) + (dispensing fee) - (co-payment) = selling price for AWP

($35.40) - ($2.12) + ($5) = $38.28

Why is Cipro fluoxetine not recommended for patients who are 60 years of age and older?

Ciprofloxacin belongs to an antibiotic class called fluoroquinolones (FQs). Ciprofloxacin and other antibiotics in this class have a boxed warning of tendinitis and tendon rupture, which is why FQs are not recommended for patients who are 60 years of age and older

What is the proper technique in cleaning of a laminar flow hood?

The proper technique is to wipe from back to front using side to side motions, away from the HEPA filter

The _____ requires the proper labeling or branding of products, and also requires that the contents of a container cannot be changed from what they are labeled to be.

FD&C Act - Food, Drug and Cosmetic Act of 1938 gives the FDA the authority to regulate the safety, effectiveness, and labeling of food, drugs, cosmetics and medical devices. PPPA deals with safety caps for prescription drugs. Hazardous Substance Labeling Act deals with the use of hazardous container for hazardous materials. Orphan Drug Act deals with drugs that are used for rare diseases.

Which of the following medication’s can be used to treat, hypertension and benign prostatic hypertrophy? Doxazosin, Carvedilol, Amlodipine, Nifedipine

All of the above medications are indicated to treat hypertension, but doxazosin (an alpha blocker) is the only one that is indicated to treat benign prostate hypertrophy. Alpha blockers relax smooth muscles, which can cause a drop in blood pressure; however, they also relax the prostatic tissue, resulting in alleviation of urinary symptoms, such as urinary urgency and nocturia.

Under what conditions is a partial fill of a Schedule II drug permissible according to the DEA?

According to the DEA, a partial fill of a Schedule II drug is permissible if the pharmacist is not able to provide the whole amount written for in the prescription. The remaining portion of the prescription may be filled within 72 hours of the first partial filling; However, if the remaining portion cannot be filled within the 72 hour period, the pharmacist shall notify the prescriber. No further quantity may be supplied beyond 72 hours without a new prescription.

The Orange Book is most commonly used to find what?

Therapeutic equivalence

A patient weighs 125lbs. A 25mg/kg loading dose of vancomycin is ordered. What is the dispensed vancomycin loading dose for this patient? (Dispensed dose is rounded to the nearest 250mg.)

1,500mg

125lbs = 125/2.2 = 56.8kg 25mg/kg x 56.8kg = 1420mg - round to 1,500mg

What is the contraindication for hydrochlorothiazide?

Sulfonamide hypersensitivity- Hydrochlorothiazide and chlorthalidone are thiazide diuretics. They are sulfonamide drugs, so hypersensitivity to sulfonamide is contraindicated. Since the drugs are diuretics, they can potentially cause renal dysfunction and electrolyte imbalance - although those are not absolute contraindications. Patients with renal issues can still be on thiazide diuretics with close monitoring.

How many milligrams of ciprofloxacin should be dispensed for the following prescription: “Ciprofloxacin 500 mg, quantity XII tablets”?

6,000mg - XII = 12. 12 tablets x 500mg = 6,000mg

Which of the following is a characteristic of disinfectant? : destroy or remove harmful microorganisms; reduce the number of bacteria; destroy fungi and viruses; destroy bacterial and fungal spores

Disinfectants destroy or remove harmful microorganisms. Sanitizers reduce the number of bacteria, fungi, and viruses. Sporicidal agents destroy bacterial and fungal spores, while sterilants destroy bacteria, viruses, fungi, and spores

Which organization oversees the “Do Not Use” abbreviations list?

The Joint Commission (TJC) introduced the official “Do Not Use” list with the goal of eliminating the use of dangerous abbreviations, acronyms, symbols, and dose designations. TJC was formerly known as the Joint Commission on Accreditation of Healthcare Organizations (JCAHO).

Which of the following methods can contribute to a reduction of medication errors?: Omit the lead leading zero; use a trailing zero; write “daily” in the sig; Write IU for International Unit

QD, Q.D., qd and q.d. Are on the joint commission’s official DO NOT USE list since they can be mistaken for QID (4 times daily) or QOD (every other day). The recommendation is to spell out “daily”.