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Water
Not usually thought of as nutrients but meets the definition requirements
Adequate ____ is critical to livestock production
water
2 basic functions of water for all terrestrial animals
Major component in body metabolism
As a major factor in body temperature control
What do all biochemical reactions that take place in an animal require?
water
Biological functions ______ property of acting as a solvent for a wide variety of compounds
water’s
Many compounds ionize readily in ____.
water
Water serves as what type of medium?
As a medium for transportation of semisolid digesta in the GI tract
Various solutes: blood, tissue fluids, cells, secretions, and in excretions such as urine and sweat
Water provides _____ of cell contents and body fluids so that relatively free movement of chemicals may occur within the cells and in the fluids and GI tract
dilution
Is water a product or substrate in hydrolysis?
substrate
Is water a product or substrate in oxidation?
product
Metabolic water is also known as _____
water of oxidation
Per gram of food, what is much higher for fat than for protein or carbohydrates?
metabolic water produced
What macronutrient produces the most metabolic water?
fat
What does metabolic water result from?
Oxidation of organic components in the cells of the body
What properties of water allow it to have an effect on temperature regulation?
High specific heat
High thermal conductivity
High latent heat of vaporization
What do the properties of water affecting temperature regulation allow for?
Accumulation of heat
Ready transfer of heat
Loss of large amounts of heat on vaporization
What liquid has the highest specific heat?
water
What does a higher specific heat allow?
greater capacity to store heat
How are sudden changes in body temperature avoided?
through the high specific heat of water
What is readily absorbed from most sections of GI tract?
water
Osmotic relationships within particular organs have ____
a marked effect on absorption
How does an increase in solutes in digesta (e.g. post-meal) affect osmotic pressure?
it increases osmotic pressure
What is body water influenced by?
age of animal & amount of fat in tissues
When body water is expressed on basis of fat-free body, water content is relatively constant across species with an average percentage of ____.
~73%
Is the greatest amount of water in body tissues present as intracellular or extracellular fluids?
intracellular fluids
Where is the remaining body water located?
the contents of GI tract & urinary tract
Amount of body water present in GI is variable are greatly affected by _____.
feed consumption
Body water decreases with ____ and has an inverse relationship with ____.
age; body fat
Is body water higher or lower in lactating cows than dry cows?
higher
Extracellular water is _____ in male calves than female calves of the same age.
greater
How much energy is required in passive diffusion?
little to no energy
Water easily passes through cell membranes & flows based on ______.
osmotic or hydrostatic pressure gradients
What extracellular fluids does water absorbed in the GI tract enter?
blood and lymph
What are volume & osmotic pressure regulated by?
thirst & antidiuretic hormone
What is water turnover used to express?
rate at which body water is excreted & replaced in tissues
Where is water available to animal’s tissues derived from?
Drinking water
Water contained in or on feed
Metabolic water
Water liberated from metabolic reactions such as condensation of amino acids to peptides
Preformed water associated with body tissues catabolized during a period of negative energy balance
Water content of _____ is highly variable
feedstuffs
As moisture content increase, what happens to water intake?
water intake decreases presenting an inverse relationship
Insensible water
water lost via vaporization from lungs & dissipation through skin
What do birds excrete instead of urea?
uric acid
Obligatory water
minimal amount of water required for excretion
What may loss of water be affected by?
fecal loss, insensible water loss, exhalation loss, & loss via sweat
When is drinking usually induced?
dehydration of body tissues, but can occur when there is no apparent need:
dry mouth/throat from reduced salivary flow
blood plasma volume
osmotic receptors
for satiety
What happens to feed consumption when temperatures reach stressing levels?
feed consumption decreases and water consumption increases
What is dry matter intake highly correlated with?
water intake at moderate temperatures
How do higher levels of protein affect water intake?
more water intake because of greater urinary excretion of excess urea
How does increased fat content affect water and salt intake?
increase water intake as well as increased salt intake
What environmental factors affect water intake?
High temperature
High humidity
Design of water dispensers
Location
Ease of access
Cleanliness
Animals consume ___ kg of water for every 1 kg of dry feed.
2-5 kg
How does decreased water quality affect water intake and feed consumption?
decrease in consumption and thus a decrease in feed consumption
What organization is responsible for upper acceptable limits of pesticide in water?
EPA
Concentrations of ____ are usually tolerated but _____ can easily reach toxic levels
nitrate; nitrite
What are carbohydrates major components in?
plant tissues
Why is the process of chloroplasts synthesizing carbs & oxygen vital for animals?
because they could not exist without this transformation of energy and free oxygen produced
How are carbohydrates classified?
on basis of number of carbon atoms per molecule of carbohydrate and basis of the number of molecules of sugar in the compound
Hexose
6-carbon sugar
Pentose
5-carbon sugar
Sugars
carbs strung together at varying lengths
What do carbohydrate primarily serve as in animals?
source of energy for normal life processes
What do carbohydrates primarily serve as in plants?
simple sugars (glucose and ribose) are involved in energy transformations and tissue synthesis
Glycans
complex carb with an important role in transmitting biochemical signals into/between cells
What are the 2 major sources of energy for the animal body?
carbs & lipids
What is the only macronutrient with no established minimum requirement for humans?
carbs
What is the ultimate source of energy for most animal cells?
glucose
What type of carbs are the only type that can be absorbed from the GI tract (except in newborns)?
monosaccharides
What increases with plant age?
lignification
What is the chief structural component in mature trees?
lignin
In ruminants and other species with large microbial populations, what does anaerobic fermentation of carbs produce?
large quantities of volatile fatty acids (VFA)
What part of small intestine has the greatest capacity to absorb monosaccharides?
Upper or proximal section of small intestine (duodenum + jejunum)
While arabinose is absorbed at the lowest rate, what two sugars are absorbed at highest rate due to established active transport?
galactose & glucose
How is glucose transported against its concentration gradient?
by coupling with sodium
Do sodium-glucose co-transporters move glucose across cell membranes with or against its concentration gradient?
against
Do facilitative glucose transporters move glucose across cell membranes with or against its concentration gradient?
with
What is fructose converted by the intestine to?
lactic acid
What type of inhibition occurs between galactose & glucose during transport across intestinal mucosal cells?
competitive inhibition
What are 2 well-understood ways to influence glucose absorption?
Reduced by short-term fasting
Increased by chronic restricted food intake
What happens as a result of the deficiency of specific disaccharides in GI tract?
serious GI upset
Endogenous (fecal metabolic) losses result in a net (apparent) absorbability approximating 80% or more in nonruminant animals. What does this mean?
Meaning, except in cases of illness, absorption of soluble carbs is similar for a wide variety of carb sources
Rate of digestion of starch can be influenced by particle size, nature of starch, interactions of starch with protein and fat and the presence of ______
antinutrients such as phylate, tannins, saponins, and enzyme inhibitors
While the body stores little energy in the form of carbs, some ______ is converted to _______, which is stored in liver and muscle tissue
glucose; glycogen
What processes allow animals maintain the narrow acceptable window of blood glucose to prevent hypo- & hyperglycemic events?
glycogenesis←→glycogenolysis
What hormones from the pancreas control blood sugar levels?
insulin & glucagon
Glycogenesis
glucose→glycogen; requires 2 ATP molecules for every 1 molecule of glucose
Gluconeogenesis
pyruvate→glucose; formed by body tissues of liver & kidneys
Glucogenic amino acids
Arginine
Methionine
Cystine
Histidine
Threonine
Tryptophan
Valine
All nonessential amino acids
Glucogenic
amino acids that give net rise to glucose when metabolized through gluconeogenesis
Ketogenic
gives rise to ketones
Ketogenic amino acids
leucine
Which type of animal, ruminants or nonruminants, constantly depend on gluconeogenesis to meet glucose needs?
ruminants
Which type of animal, ruminants or nonruminants, depend on acetate production from fermentation as major product of digestion?
ruminants
Which type of animal, ruminants or nonruminants, absorb glucose directly?
nonruminants
Which type of animal, ruminants or nonruminants, do not rely on gluconeogenesis except in long term meal deprivation?
nonruminants
What do amino acids used for gluconeogenesis or for energy enter the citric acid cycle as?
acetate, pyruvate, or α-ketoglutarate
What are the key sources of C atoms for glucose synthesis by gluconeogenesis?
lactate & pyruvate
Glycolysis
is the metabolic pathway that converts glucose into pyruvate, generating energy in the form of ATP and NADH in the process
Glycogen storage is _____
limited
What happens when ingestion of carbs exceed current needs for glycogen formation?
glucose is converted to fat
What pathway handles most glucose-6-phosphate metabolism?
glycolytic (Embden-Meyerhof) pathway
Pyruvate
an important metabolite in glucose and lipid metabolism
What is significant about the further metabolism of Acetyl-CoA occurs in Krebs or Citric acid cycle?
final common energy pathway for carbohydrate, fat, and carbon skeletons of amino acids