[PHARMACEUTICAL CALCULATIONS] PACOP VIOLET

B

1. A 15-g tube of Triamcinolone acetonide 0.025% is prescribed for one of your patients. How much

triamcinolone acetonide is present in the preparation?

A. 3.75 g

B. 3.75 mg

C. 3.5 g

D. 0.375 g

E. 0.025 mg

A

2. If a 1-lb jar of ointment contains 55 g of active ingredient, what is the percent concentration of active

ingredient in preparation?

A. 12%

B. 15%

C. 5.5%

D. 10%

E. 55%

C

3. A medication order calls for 750 mL of D5W to be infused over a 10-hour period. If an IV administration set

that delivers 10 drops/mL is to be used, how many drops per minute should be delivered to the patient?

A. 11 drops

B. 10 drops

C. 13 drops

D. 7.5 drops

E. 8 drops

A

4. An oral solution contains 75mg of active drug per ml. How many milligrams of active drug would there be in

calculated dose 0.5mL?

A. 37.5 mg

B. 50 mg

C. 75 mg

D. 7.5 mg

E. 0.5 mg

C

5. A patient is prescribed a potassium chloride elixir that contains 20 mEq of potassium ion in each 15 mL of

elixir. How many milliliters should the patient take to provide 40 mEq of potassium ion?

A. 20 mL

B. 15 mL

C. 30 mL

D. 40 mL

E. 50 mL

B

6. The recommended dose for drug is 5 mg per kg of a patient's weight. If the drug comes in a preparation

containing 15mg/5ml, what would be the dose, in mL, for a patient weighing 15 kg?

A. 30 mL

B. 25 mL

C. 15 mL

D. 10 mL

E. 20 mL

A

7. An injectable drug contains 2.5 mg of dug per 5 ml vial. If patient's dose id determined to be 150 mcg, how

many mL of the drug should be administered to the patient?

A. 0.3 mL

B. 0.5 mL

C. 0.1 mL

D. 0.2 mL

E. 0.4 mL

B

8. How many grams of digoxin would be required to make 15,000 tablets each containing 250 mcg of digoxin?

A. 500 g

B. 3.75 g

C. 2.5 g

D. 5 g

E. 15 g

A

9. An injection contains 40mg/0.8 mL of drug. How many mL should be administered to provide 75 mg of the

drug?

A. 1.5 mL

B. 2 mL

C. 7.5 mL

D. 0.4 mL

E. 0.8 mL

A

10. An oral inhalation for asthma contains 100 mcg of mometasone furoate and 5 mcg of formoterol fumarate per

inhalation. If the patient is directed to use the inhaler as "two inhalations twice daily", what would be the

amount of each drug inhaled daily? The answers should be expressed in mg.

A. 0.2 mg mometasone, 0.1 mg formoterol

B. 0.4 mg mometasone, 0.2 mg formoterol

C. 0.6 mg mometasone, 0.3 mg formoterol

D. 0.8 mg mometasone, 0.04 mg formoterol

E. 1 mg mometasone, 0.05 mg formoterol

D

11. A prefilled syringe contains 2 mg of active drug in 5 ml of solution. How many micrograms of drug is

administered by injecting 0.5 ml of the solution?

A. 0.2 mcg

B. 400 mcg

C. 0.4 mcg

D. 200 mcg

E. 215 mcg

A

12. A salbutamol inhaler contains 75 mcg of drug per inhalation. How many inhalation does could be delivered if

the inhaler contains 20 mg of salbutamol?

A. 267 inhalations

B. 250 inhalations

C. 325 inhalations

D. 472 inhalations

E. 752 inhalations

A

13. What does the abbreviation p.r.n. means?

A. As needed

B. By mouth

C. Repeat

D. At bedtime

E. As directed

B

14. An otic solution contains 0.2 mg of active ingredient in 2.5 mL containers. What is the percent strenght of the

active ingredient in the solution?

A. 0.08% w/v

B. 0.008% w/v

C. 0.04% w/v

D. 0.95%

E. None of these

B

15. Rx

Potassium permanganate 0.03%

Purified water ad. 250 mL

Sig. As directed

Determine the amount of potassium permanganate that should be used to compound the prescription.

A. 30 g

B. 0.075 g

C. 0.3 g

D. 7.5 g

E. 260 g

A

16. Rx

Ofloxacin ophthalmic solution 0.3%

Disp. 5 mL

Determine the amount in milligrams of Ofloxacin contained each mL of the prescription.

A. 3 mg

B. 3.7 mg

C. 10.2 mg

D. 12.5 mg

E. 1.72 mg

B

17. The following are the recommended doses for a certain nicotine patch

One 21 mg dose per day for 6 weeks

One 14 mg dose per day for 2 weeks

One 7 mg dose per day for 2 weeks

Determine the total quality of nicotine, in grams, that 2 patient would receive during course of therapy.

A. 11.76 g

B. 1.176 g

C. 0.168 g

D. 1.68 g

E. 117.6 g

B

18. The following are components of triphasic birth control pill:

Phase 1 6 tablets 0.05 mg levonorgestrel 0.03 mg ethinyl estradiol

Phase 2 5 tablets 0.075 mg levonorgestrel 0.04 mg ethinyl estradiol

Phase 3 10 tablets 0.125 mg levonorgestrel 0.03 mg ethinyl estradiol

7 tablets inert

If the direction is to take one tablet by mouth every day, what is the total amount of levonorgestrel and ethinyl

taken by the patient during the 28-day therapy?

A. 200 mg levonorgestrel;

1 mg ethinyl estradiol

B. 1.925 mg levonorgestrel;

0.68 mg ethinyl estradiol

C. 2.35 mg levonorgestrel;

0.75 mg ethinyl estradiol

D. 215 mg levonorgestrel;

1.78 mg ethinyl estradiol

E. 1.777 mg levonorgestrel;

1.453 mg ethinyl estradiol.

C

19. Determine the specific gravity of the liquid given the following information:

Weight of specific gravity bottle = 25.05 g

Weight of sp. Gr. Bottle whent filled with water = 73.27 g

Weight of sp. Gr. Bottle when filled with another liquid = 74.56 g

A. 1.13

B. 5.521

C. 1.027

D. 1.008

E. 0.567

A

20. If the specific gravity of 2542 mL of alcohol is 0.63, determine the weight, in grams, of the alcohol.

A. 1601 g

B. 123 g

C. 63 g

D. 473 g

E. 794 g

A

21. Determine the weight in grams of 3 fl oz of a liquid, with a specific gravity of 0.94.

A. 83.39 g

B. 95 g

C. 9.4 g

D. 30 g

E. 15 g

C

22. Determine the volume in mL of a liquid weighing 1 lb and with a specific gravity of 1.176.

A. 300 mL

B. 466 mL

C. 386 mL

D. 472 mL

E. 176 mL

D

23. Determine the cost of 500 mL of glycerin with a specific gravity of 1.25 that bought at PhP 510.00 per

kilogram.

A. PhP 300.25

B. PhP 275.00

C. PhP 297.45

D. PhP 318.75

E. PhP 523.00

A

24. Determine the cost of 3 points of a liquid with a specific gravity of 1.567, and is bought at PhP 2350.00 per

kilogram.

A. PhP 5225.40

B. PhP 6543.00

C. PhP 5376.75

D. PhP 1227.48

E. PhP 2453.87

A

25. Determine the density of 125 mL of liquid, weighing 278g.

A. 2.224

B. 3.475

C. 22.56

D. 2.232

E. 3.225

B

26. What is the weight in kilograms of 2 L of a liquid with a specific gravity of 0.97?

A. 1.75 kg

B. 1.94 kg

C. 1.27 kg

D. 1.57 kg

E. 1.87 kg

A

27. Determine the volume, in mL, of 3 lb of benzyl benzoate having a specific gravity of 1.12.

A. 1216 mL

B. 1500 mL

C. 1362 mL

D. 1000 mL

E. 2560 mL

B

28. Given the following formulation, determine the total of weight of the formula for a chewable gummy gel

medication base.

Gelatin 400g

Glycerin 150 mL (sp gr 1.25)

Purified water 25 mL

A. 75 g

B. 612.5 g

C. 325.5 g

D. 273.5 g

E. 204.5 g

C

29. If the dose of a drug is 50 mcg how many doses are in 0.04 g?

A. 250 doses

B. 750 doses

C. 800 doses

D. 415 doses

E. 525 doses

E

30. A patient has a prescription with a signa of "2 tbsp b.i.d. 8 d." What is the total volume of medication to be

dispensed to complete the therapy?

A. 240 mL

B. 180 mL

C. 300 mL

D. 500 mL

E. 480 mL

A

31. If the given dose for a given drug is 550 mcg per kilogram of the body weight, how many milligrams should be

given to a patient weighing 60 lbs.?

A. 15 mg

B. 25 mg

C. 20 mg

D. 10 mg

E. 30 mg

C

32. A patient weighing 110 lb was administered 2.3 g of a drug supposed to be dosed at 32mg/kg. Was the

administered dose correct? Or is the patient under dosed or overdosed?

A. Correct

B. Under dosed

C. Overdosed

D. Cannot be determined

E. None of these

A

33. Rx

Erythromycin ethylsuccinate 400mg/5 mL

Disp. 100 mL

Sig. Tsp q.i.d. until all medication is taken

If the dose of erythrimycin ethylsuccinate is given as 45 mg/kg/day, what would be the proper dose of the

medication on the signa for a pediatric patient weighing 40 lb?

A. ½ Tsp q.i.d. until all medication is taken

B. 1 Tsp q,i.d. until all medication is taken

C. 2 Tsp q.i.d. until all medication is taken

D. 1 ½ Tsp q.i.d. until all medication is taken

E. 2 ½ tsp q.i,d until all medication is taken

D

34. If the adult dose of a liquid medication is 0.2 ml/kg body weight, how many teaspoons should be administered

to a 170 lb patient?

A. 2 Tsp

B. 1 Tsp

C. 1 ½ Tsp

D. 3 Tsp

E. ½ Tsp

A

35. Rx

Fluconazole tablets 100 mg

Disp.______ tablets

Sig. Tab ii stat then 2.55 mg/kg bid x 7 days

How many tablets should be dispensed to a 170lb patient to complete the prescribed therapy?

A. 30 tablets

B. 15 tablets

C. 28 tablets

D. 25 tablets

E. 14 tablets

B

36. Rx

Phenytoin suspension 30 mg/ 5 mL

Disp. ______ mL

Sig. 4 mg/kg body weight daily as an anticonvulsant

Determine the amount, in mL, to be dispense to a 30 lb patient for a 30-day supply of the medication.

A. 240 mL

B. 273 mL

C. 125 mL

D. 235 mL

E. 247 mL

B

37. How many capsules each containing 500 mg of clarithromycin should be dispensed to a 165 lb patient for a

two week supply of the medication? The recommended daily for this patient is 40mg/kg/day.

A. 42 tablets

B. 84 tablets

C. 36 tablets

D. 45 tablets

E. 56 tablets

A

38. The starting pediatric dose of ritonavir is 250 mg/m2 b.i.d.

Calculate the single dose of an oral solution with 575 mg ritonavir in 8 ml solution, for a child with body

surface area of 0.72 m2 .

A. 2.5 mL

B. 5 mL

C. 7.5 mL

D. 3 mL

E. 0.5 mL

B

39. The pediatric dose of clarithromycin is 7.5 mg/kg q 12 h. Calculate the daily dose in milligrams for a child who

weighs 44 lb.

A. 150 mg per day

B. 300 mg per day

C. 350 mg per day

D. 450 mg per day

E. 600 mg per day

B

40. A prescription calls for tobramycin sulfate 1 mg/kg weight to be administered intramuscularly to a patient

weighing 180 lb. Determine the amount, in mL of injection to be administered to this patient if the available

preparation is tobramycin sulfate is 80mg/2mL

A. 1 mL

B. 2 mL

C. 3 mL

D. 0.5 mL

E. 1.5 mL

B

41. Calculate the pediatric dose for a drug with an adult dose of 120 mg for a child who is 5 years old, 40 inches

high, and weighs 35 lb. Use Young's Rule.

A. 25.24 mg

B. 35.29 mg

C. 27.13 mg

D. 28.15 mg

E. None of these

B

42. Over the counter dextromethorpan is available as 120mg/60 mL bottle. If the dose for 6 year old child is

determined to be 1 ½ teaspoons, how many milligrams of dextromethorpan is present in one dose?

A. 10 mg

B. 15 mg

C. 20 mg

D. 25 mg

E. 30 mg

A

43. A prescription for enoxaparin sodium (Lovenox) indicates a dose of 1 mg/kg subcutaneously q 12 h. The drug

is available in a prefilled syringe of 100 mg/1 mL of enoxaparin sodium. How many mL of the drug should be

administered to 218 lb patient per dose>

A. 1 mL

B. 2 mL

C. 3 mL

D. 4 mL

E. 5 mL

C

44. Cyclosporine, an immunosuppressive agent, is administered before and after organ transplant, and is given

as a single dose of 15 mg/kg body weight. How many mL of a 30 mL bottle containing 125 mg of cyclosporine

per mL would be administered to a 145 lb kidney transplant patient?

A. 3.5 mL

B. 2.7 mL

C. 7.9 mL

D. 9.2 mL

E. 5.4 mL

A

45. A prescription for digoxin indicates a dose of 10 mcg/kg for a 7 lb neonate. If the available preparation of

digoxin is 0.26mg/mL injection, how may mL should be administered to this patient?

A. 0.13 mL

B. 0.10 mL

C. 0.32 mL

D. 0.25 mL

E. 0.01 mL

C

46. How many mL of a U-100 insulin preparation should be administered to obtain a dose of 60 units of insulin?

A. 0.1 mL

B. 6 mL

C. 0.6 mL

D. 0.06 mL

E. 1 mL

D

47. Heparin sodium injection contains 200,000 units in 10 mL . How many mL would contain 8,000 units of

heparin?

A. 0.7 mL

B. 0.6 mL

C. 0.5 mL

D. 0.4 mL

E. 0.3 mL

B

48. A diabetic patient injects 30 units of insulin BID. How long would a 10 mL vial of U-100 insulin last this

patient?

A. 10 Days

B. 16 Days

C. 24 Days

D. 28 Days

E. 30 Days

C

49. Humalog contains 100 units of insulin lispro (rDNA origin)per mL . How many complete days will a 3 mL

Humalog Pen last patient who has a daily dose of 25 units BID?

A. 3 days

B. 5 days

C. 6 days

D. 8 days

E. 10 days

B

50. Saint John's Wort is administered as 100 mg capsules to be taken TID, if this herb is standardized to contain

0.5% hypericin extract, how many mg of the extract would taken daily?

A. 0.5 mg

B. 1.5 mg

C. 100 mg

D. 50 mg

E. 150 mg

A

51. A hospital medication order calls for isophane insulin suspension to be administered to a 145 lb patient on the

basis of 1 unit/kg per 24 hours. How many units of isophane insulin suspension should be administered safely

for this patient?

A. 65.9 units per 24 hours

B. 67.2 units per 24 hours

C. 66.3 units per 24 hours

D. 68.5 units per 24 hours

E. 69.1 units per 24 hours

A

52. Creon, a pancrealipase product, contains 3000 units of lipase, 9,500 units of protease, and 15,000 units if

amylase in a delayed-release capsule. The instruction is for the capsules to be swallowed whole or the

contents added uncrushed to food immidiately prior to administration.

The dose should not exceed 2,500 lipase units/kg body weight. If the content of one capsule is added to 180

ml feeding formula for 15 lb infant, is the dose within acceptable limits?

A. Yes, it is within the acceptable limits

B. No, it is not within the acceptable limits

C. It cannot be determined given the data

D. All of these.

E. None of these.

D

53. A cancer patient is taking one 30 mg oxycodone tablet q 6 h p.r.n. pain. The patient's pain management

doctor decides to switch the patient to fentanyl transdermal patches. Referring to the data below, what

strength of the patches should be prescribed to this patient ?

Daily Dose (mg/day)

Oral Oxycodone 30-67 67.5 - 112 112.5 - 157 157.5 - 202

Fentanyl TDS 25 mcg/hr 50 mcg/hr 75 mcg/hr 100 mcg/hr

A. No need to change patches

B. 25 mcg/hr

C. 50 mcg/hr

D. 75 mcg/hr

E. 100 mcg/hr

B

54. Using the Cockcroft-Gault Equation, determine the creatinine clearance rate for an 80 year old male patient

weighing 72 kg and having a serum creatinine of 1.5 mg/dL

A. 25 mL/min

B. 40 mL/min

C. 35 mL/min

D. 10 mL/min

E. 45 mL/min

B

55. A medication order indicates 1500 Units of heparin to be administered via intravenous infusion per hour. The

pharmacy provides a heparin IV bag containing 20,000 units of heparin in 250 mL D5W. Determine how many

mL should be administered per minute.

A. 0.1 mL/min

B. 0.2 mL/min

C. 0.3 mL/min

D. 0.4 mL/min

E. 0.5 mL/min

B

56. Interpret the following signa:

Sig. gtt iii each eye q 4 h p.r.n pain

A. Instill 3mL into each eye for pain

B. Instill 3 drops into each eye every 4 hours as needed for pain

C. Take 3 mL for each eye every 4 hours for pain

D. Take 3 drops for each eye four times daily as needed for pain

E. Insert 3 drops into each eye four times daily as needed for pain

C

57. Interpret the following from a medication order:

Admin. Prochlorperazine 10mg iM q 4 h p.r.n. N&V

A. Instill 10 mg prochlorperazine every four hours as needed for pain

B. Take prochlorperazine 10 mg by mouth every four hours as needed for nausea and vomiting

C. Administer 10 mg prochlorperazine intramuscularly every four hours as needed for nausea and

vomiting

D. Intramuscularly prochlorperazine 10 mg every four hours as needed

E. None of these

A

58. Interpret the following:

Potassium chloride 10 mEq po b.i.d. pc

A. Take 10 milliequivalents of potassium chloride by mouth twice daily after meals

B. Take 10 milliequivalents of potassium chloride by mouth twice daily before meals

C. Take 10 milliequivalents of potassium chloride by mouth twice daily after meals as needed.

D. Take 10 milliequivalents of potassium chloride by mouth twice at bedtime

E. None of the above

B

59. A prescription for Drug A was brought to the pharmacy, indication the following:

1 tablet q.i.d. the first day

1 tablet t.i.d. the second day

1 tablet b.i.d. x 7 days

1 tablet q.d. thereafter

How many tablets should be dispensed for a 60- day supply if this medication?

A. 75 tablets

B. 72 tablets

C. 77 tablets

D. 21 tablets

E. 42 tablets

C

60. Interpret the following:

Ii tabpo q.6.h ATC pain

A. Take two tablets every 6 hours around the clock as needed for pain

B. Instill two tablets by mouth for times a day as needed for pain

C. Take two tablets by mouth every 6 hours around the clock for pain

D. Take two tablets as needed for pain around the clock

E. None of these

A

61. A capsule contains the following amounts of medicinal agents: 0.025 g, 15 mg, 0.0003 g, 2 mg, and 125 mg.

Determine the total weight of the medicinal agents in the capsule.

A. 167.3 g

B. 15.025 g

C. 325 mg

D. 15.025 mg

E. 167.3 mg

D

62. An intravenous solution contains 300 mcg of the drug per mL . How many milligrams of the drug would a

patient receive from an IV infusion of 1500 mL of the solution?

A. 250 mg

B. 500 mg

C. 300 mg

D. 450 mg

E. 150 mg

B

63. One- half liter of solution for intravenous infusion contains 3 g of drug. How many mL of the infusion would

contain 0.7 mg of drug?

A. 1.117 mg

B. 0.117 mg

C. 30 mg

D. 0.7 mg

E. 0.2 mg

B

64. A salbutamol inhaler contains 20 mg of drug. How many inhalation does can be delivered if each inhalation

contains 100 mcg?

A. 100 inhalations

B. 200 inhalations

C. 250 inhalations

D. 300 inhalations

E. 400 inhalations

C

65. A patient was administered 200 mL of D5W at a rate of 20mL/hr. If the infusion was begun at 10 AM, what

time was the infusion completed?

A. 10 PM

B. 6 PM

C. 8 PM

D. 2 PM

E. 12 PM

A

66. A pediatric is administered 75 mL of an infusion at 10 drops/min . Determine the duration of the infusion in

minutes if an administration set that delivers 30 drops/mL is used?

A. 450 minutes

B. 400 minutes

C. 350 minutes

D. 300 minutes

E. 350 minutes

C

67. An emergency syringe contains 1 g/5 of lidocaine. How many mL should be used to prepare 125 mL of an

infusion to contain 2 mg/mL of lidocaine in D5W?

A. 2.25 mL

B. 2.0 mL

C. 1.25 mL

D. 1.5 mL

E. 1.0 mL

A

68. An intravenous drip contains 3 g lidocaine hydrochloride and is administered t a rate of 5 mg/min. What is the

total time, in minutes, to complete the infusion?

A. 600 minutes

B. 500 minutes

C. 400 minutes

D. 300 minutes

E. 200 minutes

B

69. A 160 lb patient has been administered intravenous immunoglobulin (IVIG) at a rate of 0.05 mL/kg/min. How

many mL is administered over a period of 6 hours?

A. 1420 mL

B. 1309 mL

C. 1255 mL

D. 1150 mL

E. 1030 mL

B

70. A pharmacist receives a medication order for 400,000 units of penicillin G potassium to be added to 500 mL of

D5W. The direction on the vial reads that if 1.5 mL of solvent is added, the solution, containing 1,000,000 units

will now measure 2 mL . Determine the amount of solution that should be added to D5W?

A. 0.5 mL

B. 0.8 mL

C. 1 mL

D. 1.25 mL

E. 2 mL

C

71. A medication order indicates 1.5g of an antibiotic to be added to 1000 ml of D5W. How many mL of a 250mg/3

mL injection should be added to the D5W to prepare this medication order?

A. 12 mL

B. 15 mL

C. 18 mL

D. 20 mL

E. 22 mL

D

72. In addition to the active ingredient in an oral solution, it also contain 40.5% of alcohol and 23.8% propylene

glycol. Determine the quantities of the two ingredients in a 240 mL bottle of oral solution.

A. 77.3 mL alcohol; 57.12 mL propylene glycol

B. 97.2 mL alcohol; 67.4 propylene glycol

C. 79.4 mL alcohol; 47.62 mL propylene glycol

D. 97.2 mL alcohol; 57.12 mL propylene glycol

E. 87.3 mL alcohol; 45.6 mL propylene glycol

A

73. If 240 ml of ranitidine syrup contains 2.3 g if ranitidine, how many mg of ranitidine would've been administered

in a patient who takes 1 teastpoonful of the syrup?

A. 47.9 mg

B. 50.3 mg

C. 42.7 mg

D. 51.8 mg

E. 45.2 mg

B

74. If a pediatric patient requires a 0.02 mg dose of digoxin, what volume of an 80 mcg per mL injection should be

administered?

A. 0.5 mL

B. 0.25 mL

C. 0.75 mL

D. 0.8 mL

E. 1 mL

C

75. A patient with glaucoma brings a prescription for Alphagan P with a signa of one drop in the affected eye(s)

three times daily. Alphagan P contains 0.15% brimonidine tartrate per 10 mL bottle. How many mg of

brimonidine tartrate is administered daily if the patient is treat both eyes, and the dropper used delivers 20

drops per mL?

A. 0.25 mg

B. 0.3 mg

C. 0.45 mg

D. 0.55 mg

E. 0.6 mg

E

76. A fluticasone nasal spray preparation contains 45 mcg of fluticasone propionate per actuation spray in each

100 mg formulation. How many mg of fluticasone propionate is contained in each container if each container

provides 100 sprays?

A. 5mg

B. 3 mg

C. 10 mg

D. 4.5 mg

E. 4 mg

C

77. If the normal daily dose for gentamicin is 3 mg/kg/day, and administered in three divided doses, what would

be the single (8 hour) dose for a 123 lb patient and scheduled to receive 45% of the usual dose based on

renal impairment?

A. 32.08 mg

B. 20.15 mg

C. 25.16 mg

D. 28.25 mg

E. 75.5 mg

A

78. Determine how many teaspoonfuls of an oral solution should be administered to a 145-lb patient if the

recommended adult dose is 0.3 mL/kg.

A. 4 tsp

B. 8 tsp

C. 6 tsp

D. 2 tsp

E. 3 tsp

A

79. A 45-lb child has been prescribed with dimenhydrinate, where the labelled dose of the drug reads 1.3mg/kg.

The available oral solution contains 12.5 mg/5 mL of dimenhydrinate. The nurse checked the hospital

pharmacist if her calculated dose of 10.6 mL is correct. What would you tell her?

A. Her calculations are correct.

B. Her calculations are incorrect.

C. Her calculations have no basis

D. None of these

E. All of these

B

80. A 145-lb patient was receiving filgrastim in doses of 10 mcg/kg/day. When the blood test results arrive, her

dose was lowered to 7 mcg/kg/day. If an injection containing 0.3 mg filgrastim per 0.5 mL is used, determine

the previous and new dose to be administered to this patient.

A. 2 mL previous dose; 1 mL new dose

B. 1.1 mL previous dose; 0.92 mL new dose

C. 1.75 mL previous dose; 0.87 mL new dose

D. 3.4 mL previous dose; 1 mL new dose

E. 1 mL previous dose; 0.68 mL new dose

A

81. If the pediatric dose for an antibiotic is "7 mg/kg q 12 h", what is the daily dose in mg for a child weighing 47

lb?

A. 299 mg per day

B. 459 mg per day

C. 377 mg per day

D. 257 mg per day

E. 302 mg per day

B

82. If the daily dose of an antibiotic for a pediatric patient is 314 mg/day, how many teaspoons should be

administered if a suspension containing 125mg/5 mL is given to the patient?

A. 2 tsp

B. 2 ½ tsp

C. 3 tsp

D. 3 ½ tsp

E. 4 tsp

C

83. What is the daily dose in mg for a child with a BSA of 0.45 m2 if the recommended dose is 8 mg/m2/day?

A. 4.5 mg/day

B. 5.9 mg/day

C. 3.6 mg/day

D. 2.8 mg/day

E. 1.2 mg/day

B

84. A patient receives an injection of ant anticoagulant drug at a dose of 20 mg prior to hip replacement surgery.

After the surgery drug is injected at a dose of 1mg/kg, what is the total pre- and post- surgery doses for this

patient who weighs 138 lb?

A. 25 mg

B. 83 mg

C. 63 mg

D. 55 mg

E. 76 mg

A

85. If the recommended pediatric dose for cefexime is 7.5 mg/kg/day, how many mL should be dispensed for a

10-day course of therapy for a 50-lb patient? The available preparation on the pharmacy is 100mg/5 mL.

A. 90 mg

B. 50 mg

C. 63 mg

D. 55 mg

E. 76 mg

E

86. Androgel 1.6% is a testoterone gel for topical use. Determine the number grams required to provide a 48.6 mg

dose of testosterone.

A. 1.5 g

B. 2 g

C. 4.8 g

D. 1.6 g

E. 3 g

A

87. Determine the amount in milligrams of methylparaben needed to prepare to 8 fluidounces of a solution

containing 0.12% w/v of methylparaben.

A. 283.87 mg

B. 255.23 mg

C. 274.33 mg

D. 215.57 mg

E. 229.72 mg

A

88. The contents of eight 75 mg oseltamivir (Tamiflu) capsules were emptied into a liquid vehicle to prepare 60 ml

of suspension. What is the percent strength of oseltamivir in the preparation.

A. 1%

B. 1.5%

C. 6 %

D. 7.5%

E. 2%

B

89. Beractant suspension is available in a 4 mL vial containing 25 mg of drug per mL, and dose is 100 mg/kg of

birthweight. This is administered via intratracheal route to premature infants within 15 minutes of birth, as

indicated, for the prevention and treatment of respiratory distress syndrome. What is the dose for a new born

weighing 4.5 lbs?

A. 4.5 mL

B. 8.18 mL

C. 4 mL

D. 5.25 mL

E. 9 mL

D

90. What would be the quantities for a 176-lb patient of the neurologic drug divalproex solution if the

recommended initial dose is 25 mg/kg/day to be increased as indicated to a maximum dose 60 mg/kg/day.

A. 2500 mg/day initial, 6000 mg/day max

B. 3050 mg/day initial, 4800 mg/day max

C. 1500 mg/day initial, 3000 mg/day max

D. 2000 mg/day initial, 4800 mg/day max

E. 2000 mg/day initial, 2500 mg/day max

B

91. As a pharmacist what strength tablet and quantity would you recommend for an initial dose of 2000 mg of

divalproex sodium, if the drug comes in 250 ng and 500 mg strength tablets?

A. Five 250 mg tablets, as initial dose

B. Four 500 mg tablets, as initial dose

C. Two 1000 mg tablet as initial dose

D. Two 500 mg tablets as initial dose

E. Seven 250 mg tablets as initial dose

E

92. A prescription indicates 3 million units of penicillin daily for 1 week. If 1 unit of penicillin G potassium equals to

0.9 mcg/mg, How many 250 mg tablets should be dispensed to complete the therapy?

A. 11 tablets

B. 7 tablets

C. 21 tablets

D. 35 tablets

E. 77 tablets

A

93. Adult doses of calcitonin of up to 32 units per kilogram do not produce any adverse effects. If a 140 lb patient

were administered 0.8 mL injection, would adverse effects to be observed? Note that calcitonin is available as

200 international units per milliliter injection.

A. NO

B. Yes

C. There is not enough data to tell

D. Maybe

E. Not applicable

A

94. What would be the days supply for a 10 mL vial of insulin glargine(Lantus), 100 units/mL . If a patient's

starting dose is 15 units, and a daily maintenance dose of 8 units?

A. 30 Days

B. 15 Days

C. 124 Days

D. 45 Days

E. 60 Days

C

95. Determine the creatinine for this patient using Jeliffe equation:

Gender: Male Age: 54 years old

Weight: 75 kg Serum creatinine: 1.2 mg/dL

A. 12 mL/minute

B. 75 mL/minute

C. 59 mL/minute

D. 54 mL/minute

E. 98 mL/minute

A

96. Using the Cockcroft-Gault Equation, determine the creatinine clearance rate for an 80- year old male patient

weighing 75 kg with a serum creatinine of 1.7 mg/dL

A. 36.76 mL/minute

B. 75.12 mL/minute

C. 60.27 mL/minute

D. 84.50 mL/minute

E. 14.72 mL/minute

B

97. Using Cockcroft-Gault Equation, determine the creatinine clearance rate for this patient:

Gender: Female Age: 75 years old

Weight: 70 kg Serum Creatinine: 1 mg/dL

A. 63.9 mL/minute

B. 53.72 mL/minute

C. 72 mL/minute

D. 56.9 mL/minute

E. 14.72 mL/minute

C

98. A hospital pharmacy order indicates 4000 units of heparin to be administered SC twice daily for the prevention

of blood clots. The pharmacist has obtained a vial of heparin containing 15000 heparin units per mL.

Determine the amount, in mL, of the injection that should be administered for each dose

A. 0.15 mL

B. 0.54 mL

C. 0.27 mL

D. 0.4 mL

E. 0.75. mL

A

99. Determine the ideal body weight (IBW) in pounds or a 72 year old female patient who is 5 feet 8 inches tall

and weighs 164 pounds

A. 120 lb

B. 164 lb

C. 125 lb

D. 100 lb

E. 170 lb

B

100. Determine the IBWin kilogram for a 65 year old male patient who is 8 inches tall and weighs 164 lb

A. 74.6 kg

B. 68.4 kg

C. 95.3 kg

D. 65.7 kg

E. 45.21 kg