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Which system works most closely with the endocrine system to maintain homeostasis?
A) Respiratory system
B) Nervous system
C) Digestive system
D) Urinary system
E) Lymphatic system
B) Nervous system
Endocrine glands differ from exocrine glands because endocrine glands:
A) Have ducts
B) Release only digestive enzymes
C) Release hormones into interstitial fluid and blood
D) Release secretions onto body surfaces
E) Produce only steroid hormones
C) Release hormones into interstitial fluid and blood
Which structure controls the anterior pituitary by releasing regulatory hormones?
A) Thyroid gland
B) Hypothalamus
C) Pineal gland
D) Adrenal cortex
E) Pancreas
B) Hypothalamus
Which anterior pituitary hormone stimulates the thyroid gland?
A) ACTH
B) FSH
C) TSH
D) GH
E) ADH
C) TSH
Which anterior pituitary hormone stimulates the adrenal cortex?
A) ACTH
B) TSH
C) Prolactin
D) Oxytocin
E) FSH
A) ACTH
Which hormone primarily stimulates general body growth?
A) Calcitonin
B) Growth hormone
C) Aldosterone
D) Insulin
E) Melatonin
B) Growth hormone
Which hormone is released from the posterior pituitary and increases water reabsorption by the kidneys?
A) TSH
B) ACTH
C) ADH
D) GH
E) FSH
C) ADH
Oxytocin is most directly involved in:
A) Lowering blood glucose
B) Increasing blood calcium
C) Uterine contractions and milk ejection
D) Increasing BMR
E) Increasing sodium retention
C) Uterine contractions and milk ejection
Which gland produces melatonin?
A) Thyroid
B) Pineal
C) Pituitary
D) Thymus
E) Adrenal
B) Pineal
Melatonin is particularly important for regulating:
A) Blood calcium
B) Blood glucose
C) Sleep and circadian rhythms
D) Sodium concentration
E) RBC production
C) Sleep and circadian rhythms
Which hormones increase basal metabolic rate?
A) T3 and T4
B) Insulin and glucagon
C) FSH and LH
D) ADH and oxytocin
E) PTH and calcitonin
A) T3 and T4
Which hormone lowers blood calcium levels?
A) PTH
B) Calcitriol
C) Calcitonin
D) Aldosterone
E) Cortisol
C) Calcitonin
Which hormone increases blood calcium concentration?
A) Calcitonin
B) Parathyroid hormone
C) Insulin
D) Melatonin
E) Prolactin
B) Parathyroid hormone
The major mineralocorticoid secreted by the adrenal cortex is:
A) Cortisol
B) Aldosterone
C) Epinephrine
D) Glucagon
E) Testosterone
B) Aldosterone
Aldosterone primarily causes the kidneys to increase reabsorption of:
A) Sodium
B) Glucose
C) Calcium
D) Urea
E) Bilirubin
A) Sodium
Which hormone is the major glucocorticoid?
A) Insulin
B) Cortisol
C) Aldosterone
D) Calcitonin
E) Melatonin
B) Cortisol
Which is NOT a typical effect of glucocorticoids?
A) Increased glucose formation
B) Protein breakdown
C) Fat breakdown
D) Reduction of inflammation
E) Increased production of every type of blood cell
E) Increased production of every type of blood cell
Which pancreatic cells produce insulin?
A) Alpha cells
B) Beta cells
C) Delta cells
D) Acinar cells
E) F cells
B) Beta cells
Which pancreatic cells produce glucagon?
A) Alpha cells
B) Beta cells
C) Delta cells
D) Chief cells
E) Parietal cells
A) Alpha cells
A decrease in blood glucose stimulates secretion of:
A) Insulin
B) Calcitonin
C) Glucagon
D) Aldosterone
E) Prolactin
C) Glucagon
True or False: Insulin decreases blood glucose concentration.
True
Excessive thyroid hormone would most likely cause:
A) Decreased metabolic rate
B) Weight gain from reduced metabolism
C) Increased metabolic rate and possible weight loss
D) Decreased body temperature
E) Decreased cellular respiration
C) Increased metabolic rate and possible weight loss
Blood is classified as which type of tissue?
A) Epithelial
B) Nervous
C) Connective
D) Muscle
E) Adipose
C) Connective
Approximately what percentage of whole blood is plasma?
A) 25%
B) 35%
C) 45%
D) 55%
E) 75%
D) 55%
Formed elements make up approximately what percentage of blood?
A) 10%
B) 25%
C) 45%
D) 55%
E) 90%
C) 45%
The percentage of total blood volume occupied by RBCs is called the:
A) Differential count
B) Hematocrit
C) Hemostasis
D) Hemolysis
E) Plasma volume
B) Hematocrit
Plasma is composed primarily of:
A) Protein
B) Glucose
C) Water
D) RBCs
E) Electrolytes
C) Water
Which plasma protein contributes most importantly to blood osmotic pressure?
A) Albumin
B) Hemoglobin
C) Fibrin
D) Myoglobin
E) Transferrin
A) Albumin
Which category of plasma proteins includes antibodies?
A) Albumins
B) Globulins
C) Fibrinogens
D) Hemoglobins
E) Myoglobins
B) Globulins
Which plasma protein is important for blood clotting?
A) Albumin
B) Fibrinogen
C) Hemoglobin
D) Myoglobin
E) Insulin
B) Fibrinogen
Mature erythrocytes normally:
A) Contain large nuclei
B) Have no nucleus
C) Divide by mitosis
D) Produce antibodies
E) Become macrophages
B) Have no nucleus
The biconcave shape of erythrocytes helps:
A) Reduce oxygen transport
B) Increase surface area for gas exchange
C) Produce antibodies
D) Cause clotting
E) Produce leukocytes
B) Increase surface area for gas exchange
The oxygen-binding portion of hemoglobin is the:
A) Globin
B) Heme
C) Albumin
D) Fibrin
E) Plasma
B) Heme
The iron found in hemoglobin directly binds:
A) Carbon dioxide
B) Oxygen
C) Nitrogen
D) Glucose
E) Sodium
B) Oxygen
Normal RBC life span is approximately:
A) 10 days
B) 30 days
C) 60 days
D) 120 days
E) 365 days
D) 120 days
Old erythrocytes are primarily removed by macrophages in the:
A) Pancreas and kidneys
B) Spleen and liver
C) Thyroid and thymus
D) Heart and lungs
E) Stomach and intestine
B) Spleen and liver
Which hormone stimulates erythrocyte production?
A) TPO
B) EPO
C) TSH
D) ADH
E) ACTH
B) EPO
Hematopoiesis occurs primarily in:
A) Yellow bone marrow
B) Red bone marrow
C) Cartilage
D) Lymph
E) Plasma
B) Red bone marrow
Which formed element is primarily responsible for reducing blood loss after vessel injury?
A) Erythrocyte
B) Platelet
C) Lymphocyte
D) Eosinophil
E) Monocyte
B) Platelet
Which leukocyte commonly becomes a macrophage after entering tissues?
A) Basophil
B) Monocyte
C) Eosinophil
D) Lymphocyte
E) Platelet
B) Monocyte
Which leukocyte is most closely associated with releasing substances that promote inflammation?
A) Basophil
B) Erythrocyte
C) Platelet
D) Monocyte
E) Lymphocyte
A) Basophil
Which leukocyte is associated with destroying antigen-antibody complexes and combating parasites?
A) Basophil
B) Eosinophil
C) Monocyte
D) Platelet
E) Erythrocyte
B) Eosinophil
A person with type O blood has which antibodies in plasma?
A) Anti-A only
B) Anti-B only
C) Both anti-A and anti-B
D) Neither anti-A nor anti-B
E) Anti-Rh only
C) Both anti-A and anti-B
True or False: A person with type AB blood has both A and B antigens on the RBC surface.
True
The heart is located primarily within the:
A) Abdominal cavity
B) Mediastinum
C) Pelvic cavity
D) Cranial cavity
E) Vertebral cavity
B) Mediastinum
The apex of the heart points:
A) Superiorly and right
B) Inferiorly and left
C) Directly posteriorly
D) Superiorly and left
E) Inferiorly and right
B) Inferiorly and left
The tough outer portion of the pericardium is the:
A) Endocardium
B) Fibrous pericardium
C) Myocardium
D) Visceral pleura
E) Tunica externa
B) Fibrous pericardium
Pericardial fluid primarily:
A) Increases friction
B) Reduces friction as the heart beats
C) Causes cardiac contraction
D) Carries oxygen
E) Produces action potentials
B) Reduces friction as the heart beats
Which layer is both part of the heart wall and the visceral layer of the serous pericardium?
A) Endocardium
B) Myocardium
C) Epicardium
D) Fibrous pericardium
E) Parietal pericardium
C) Epicardium
The thick muscular middle layer of the heart is the:
A) Epicardium
B) Myocardium
C) Endocardium
D) Pericardium
E) Endothelium
B) Myocardium
Which heart chamber has the thickest myocardium?
A) Right atrium
B) Left atrium
C) Right ventricle
D) Left ventricle
E) All are equal
D) Left ventricle
Why is the left ventricular wall thicker than the right ventricular wall?
A) It receives venous blood
B) It pumps through the systemic circulation
C) It pumps only to the lungs
D) It contains the SA node
E) It contains less blood
B) It pumps through the systemic circulation
Blood returning from systemic circulation first enters the:
A) Left atrium
B) Right atrium
C) Left ventricle
D) Right ventricle
E) Pulmonary trunk
B) Right atrium
Blood returning from the lungs first enters the:
A) Right atrium
B) Right ventricle
C) Left atrium
D) Left ventricle
E) Aorta
C) Left atrium
Which valve lies between the right atrium and right ventricle?
A) Mitral
B) Aortic
C) Tricuspid
D) Pulmonary
E) Bicuspid
C) Tricuspid
Which valve lies between the left atrium and left ventricle?
A) Tricuspid
B) Pulmonary semilunar
C) Mitral
D) Aortic semilunar
E) Coronary
C) Mitral
The pulmonary semilunar valve prevents blood from returning from the:
A) Aorta into the left ventricle
B) Pulmonary trunk into the right ventricle
C) Right ventricle into the right atrium
D) Left ventricle into the left atrium
E) Vena cava into the right atrium
B) Pulmonary trunk into the right ventricle
Chordae tendineae attach the AV valve cusps to the:
A) SA node
B) Papillary muscles
C) Semilunar valves
D) Aorta
E) Interatrial septum
B) Papillary muscles
Contraction of papillary muscles helps prevent:
A) Opening of semilunar valves
B) AV valve prolapse into the atria
C) Blood entering the ventricles
D) Depolarization
E) Blood entering the coronary circulation
B) AV valve prolapse into the atria
The normal pacemaker of the heart is the:
A) AV node
B) SA node
C) Bundle of His
D) Purkinje fibers
E) Medulla
B) SA node
Which sequence correctly represents the cardiac conduction pathway?
A) AV node → SA node → Purkinje fibers → bundle branches
B) SA node → AV node → AV bundle → bundle branches → Purkinje fibers
C) Purkinje fibers → SA node → AV node → AV bundle
D) SA node → Purkinje fibers → AV node → ventricles
E) AV bundle → SA node → AV node → Purkinje fibers
B) SA node → AV node → AV bundle → bundle branches → Purkinje fibers
On an ECG, the P wave represents:
A) Ventricular depolarization
B) Atrial depolarization
C) Ventricular repolarization
D) Atrial repolarization only
E) Valve closure
B) Atrial depolarization
The QRS complex represents:
A) Atrial depolarization
B) Ventricular depolarization
C) Ventricular repolarization
D) Atrial filling
E) Semilunar valve closure
B) Ventricular depolarization
The T wave represents:
A) Atrial depolarization
B) Ventricular depolarization
C) Ventricular repolarization
D) SA node firing only
E) AV valve opening
C) Ventricular repolarization
Parasympathetic stimulation through the vagus nerve causes:
A) Increased heart rate
B) Decreased heart rate
C) Increased blood viscosity
D) Increased blood volume
E) Ventricular fibrillation
B) Decreased heart rate
Cardiac output equals:
A) HR ÷ SV
B) HR × SV
C) EDV + ESV
D) SV ÷ HR
E) BP × resistance
B) HR × SV
Which vessels carry blood away from the heart?
A) Veins
B) Arteries
C) Venules
D) Capillaries
E) Sinusoids
B) Arteries
Which vessels return blood toward the heart?
A) Arteries
B) Arterioles
C) Veins
D) Capillaries
E) Metarterioles
C) Veins
The innermost layer of a blood vessel is the:
A) Tunica externa
B) Tunica media
C) Tunica interna
D) Myocardium
E) Endocardium
C) Tunica interna
Which blood-vessel layer contains large amounts of smooth muscle?
A) Tunica interna
B) Tunica media
C) Tunica externa
D) Endothelium only
E) Basement membrane
B) Tunica media
Vasoconstriction is mainly produced by contraction of smooth muscle in the:
A) Tunica interna
B) Tunica media
C) Tunica externa
D) Capillary basement membrane
E) Endocardium
B) Tunica media
Arterioles are known as resistance vessels because they:
A) Have valves
B) Strongly regulate vessel diameter and blood flow
C) Carry the greatest blood volume
D) Lack smooth muscle
E) Have the thinnest walls
B) Strongly regulate vessel diameter and blood flow
Vasodilation causes vessel diameter to:
A) Decrease
B) Increase
C) Remain unchanged
D) Completely close
E) Reverse blood flow
B) Increase
Which are the main exchange vessels?
A) Arteries
B) Arterioles
C) Capillaries
D) Veins
E) Venules
C) Capillaries
Capillary walls are well suited for exchange because they are:
A) Thick and muscular
B) Very thin
C) Covered with cartilage
D) Highly keratinized
E) Made of skeletal muscle
B) Very thin
Which capillary type has pores that allow greater exchange and is found in organs such as the kidneys?
A) Continuous
B) Fenestrated
C) Muscular
D) Elastic
E) Venous
B) Fenestrated
Which capillaries have large openings and an incomplete basement membrane?
A) Continuous capillaries
B) Fenestrated capillaries
C) Sinusoids
D) Arterioles
E) Venules
C) Sinusoids
Precapillary sphincters regulate:
A) Heart rate
B) Blood flow through capillary beds
C) Formation of RBCs
D) Blood clotting
E) Venous valves
B) Blood flow through capillary beds
Blood hydrostatic pressure tends to:
A) Pull fluid into capillaries
B) Push fluid out of capillaries
C) Destroy RBCs
D) Close veins
E) Decrease filtration
B) Push fluid out of capillaries
Blood colloid osmotic pressure tends to:
A) Push fluid out of capillaries
B) Pull fluid into capillaries
C) Close capillary beds
D) Increase RBC production
E) Cause vasoconstriction
B) Pull fluid into capillaries
A decrease in plasma proteins would most likely contribute to:
A) Increased reabsorption
B) Edema
C) Increased blood colloid osmotic pressure
D) Reduced filtration
E) Increased hematocrit
B) Edema
Which factor most strongly assists venous return from the limbs?
A) Skeletal muscle activity
B) Hematocrit
C) Plasma proteins
D) RBC destruction
E) Platelet activation
A) Skeletal muscle activity
Valves in veins primarily:
A) Increase arterial pressure
B) Prevent backward blood flow
C) Cause vasoconstriction
D) Produce blood cells
E) Perform gas exchange
B) Prevent backward blood flow
An increase in blood viscosity generally causes vascular resistance to:
A) Decrease
B) Increase
C) Remain unchanged
D) Become zero
E) Reverse
B) Increase
Which variable most directly increases resistance when it decreases?
A) Blood-vessel lumen diameter
B) Blood oxygen
C) Plasma glucose
D) Heart size
E) Body temperature
A) Blood-vessel lumen diameter
A decrease in baroreceptor firing caused by low blood pressure produces:
A) Increased parasympathetic stimulation
B) Increased sympathetic stimulation
C) Lower heart rate
D) Lower contractility
E) Vasodilation only
B) Increased sympathetic stimulation
The radial artery is commonly used to measure a pulse at the:
A) Neck
B) Wrist
C) Ankle
D) Groin
E) Chest
B) Wrist
A blockage of the external iliac artery would most directly reduce blood flow into the:
A) Renal artery
B) Femoral artery
C) Carotid artery
D) Mesenteric artery
E) Coronary artery
B) Femoral artery
One major function of the lymphatic system is to:
A) Pump blood
B) Drain excess interstitial fluid
C) Produce bile
D) Produce urine
E) Secrete insulin
B) Drain excess interstitial fluid
Specialized lymphatic capillaries in the small intestine that absorb dietary lipids are called:
A) Sinusoids
B) Lacteals
C) Venules
D) Alveoli
E) Glomeruli
B) Lacteals
Interstitial fluid is called lymph once it:
A) Enters blood capillaries
B) Enters lymphatic vessels
C) Enters the stomach
D) Reaches the kidneys
E) Reaches the liver
B) Enters lymphatic vessels
Lymphatic capillaries begin as:
A) Closed-ended tubes
B) Arteries
C) Veins
D) Open cavities connected to the heart
E) Ventricles
A) Closed-ended tubes
Which duct drains most of the body?
A) Right lymphatic duct
B) Thoracic duct
C) Cystic duct
D) Pancreatic duct
E) Common bile duct
B) Thoracic duct
The right lymphatic duct drains the:
A) Entire lower body
B) Right upper portion of the body
C) Entire left side
D) Abdominal organs only
E) Lower limbs only
B) Right upper portion of the body
The thoracic duct ultimately returns lymph near the:
A) Left subclavian vein
B) Right femoral vein
C) Inferior vena cava
D) Pulmonary trunk
E) Aorta
A) Left subclavian vein
Which lymphatic trunk drains the head and neck?
A) Lumbar
B) Jugular
C) Intestinal
D) Bronchomediastinal
E) Subclavian
B) Jugular
Which lymphatic trunk primarily drains the upper extremity?
A) Jugular
B) Intestinal
C) Subclavian
D) Lumbar
E) Bronchial
C) Subclavian
Which organ filters blood rather than lymph?
A) Lymph node
B) Spleen
C) Tonsil
D) Thymus
E) Lacteal
B) Spleen
The spleen contains:
A) Gray and white matter
B) Red and white pulp
C) Cortex and medulla only
D) Glomeruli and tubules
E) Alveoli and bronchioles
B) Red and white pulp
Which is NOT considered a lymphatic organ or structure?
A) Spleen
B) Thymus
C) Lymph node
D) Pancreas
E) Tonsil
D) Pancreas