Blood Transfusion Lecture Series: Blood Donation and Storage

Comprehensive vocabulary flashcards covering blood donor selection, screening, collection procedures, storage conditions, and donation types based on the lecture series.

Donor Age Requirement

The acceptable age range for prospective blood donors is between 18 and 65 years.

Donation Interval

The required minimum time between blood donations is at least 12 weeks.

Live-attenuated virus vaccine deferral

A donor is acceptable only after 2 weeks or when the scab has fallen off following vaccines such as yellow fever, mumps, measles (rubeola), oral polio, or smallpox.

German measles (rubella) deferral

The deferral period for a donor who received a rubella vaccine is 4 weeks.

Rabies vaccine deferral

Donors who received a rabies vaccine following a bite by a rabid dog must be deferred for 1 year.

Hepatitis B immunoglobulin deferral

The deferral period after receiving hepatitis B immunoglobulin is 1 year.

Donor Physical Requirements

A donor must have a minimum height of $1.5M$ and a weight above $50Kg$.

Copper sulphate method

A method of Hb estimation based on Specific Gravity where a solution of $S.G. 1.053 = 12.5 g/dl$ for females and $1.055 = 13.5 g/dl$ for males.

TTIs

Transfusion Transmissible Infections, which are routinely screened for and include HIV 1 & 2, HBV, HCV, and Syphilis (T. pallidum).

Adult Blood Bag Volume

Contains $450-495 mils$ of blood, including $63 mls$ of anticoagulant.

Fainting First Aid

The patient should lie on their back with feet raised above the head, have tight clothing loosened, and may inhale aromatic spirit.

Hyperventilation donor care

Often caused by nervousness, it is managed by diverting the donor's attention or having them breathe into a paper bag.

Haematoma management

At the first sign of swelling, the tourniquet and needle must be removed, sterile gauze and a firm dressing applied, and ice used if necessary.

Heparin storage life

Blood stored with Heparin as an anticoagulant has a shelf life of 7 days.

Acid Citrate Dextrose (ACD) storage life

Blood stored with ACD has a shelf life of 21 days.

Citrate Phosphate Dextrose (CPD) storage life

Blood stored with CPD has a shelf life of 28 days.

Citrate Phosphate Dextrose – Adenine (CPD-A) storage life

Blood stored with CPD-A has a shelf life of 35 days.

Saline Adenine Glucose Mannitol (SAGM) storage life

Blood stored with SAGM has a shelf life of 42 days.

Storage Lesions

Changes in stored blood including decreased RBC viability (depletion of ATP), diminished $2, 3 – DPG$ levels, potassium leakage, decreased pH, and shape changes to echinocytes.

Homologous Blood Donation

The donation of blood intended for use by a person other than the donor.

Autologous Blood Donation

The practice of collecting and reinfusing a patient's own blood or blood components.

Intra-Operative Auto Transfusion

Whole blood collected from a body cavity during surgery, anticoagulated, filtered, washed, and re-infused to the patient.

Acute Normovolaemic Haemodilution

Collection of whole blood in theatre before surgery, replaced by colloid or crystalloid solution to decrease blood viscosity and improve microcirculation.

Pre-deposit Hb requirement

For pre-deposit autologous donation, the donor's Hb should not be less than $11 g/dl$.

Leap-frog method

A technique for pre-deposit collection that allows for the accumulation of up to 9 units of blood.

Directed Donation

The provision of blood for a recipient by a named selected donor, such as a friend or relative.

Haemapheresis

A procedure where blood is withdrawn, a specific component (plasma, platelets, RBCs, or WBCs) is removed, and the remaining components are returned to the donor.

Erythrocytapheresis

A form of apheresis specifically for the removal of red cells from the blood.