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What is the pattern of inheritance for sickle cell anemia? Describe the phenotype of a heterozygous individual then explain what benefits this phenotype provides them with
Codominant
some sickle cells and some normal cells
resistance to malaria
Which individuals above are carriers for sickle anemia? Why does their blood travel the way it does?
Their blood travels the way it does because they are stiff and sticky, meaning they do not move smoothly through blood vessels and clump together.
What are two potential uses for CRISPR? give one advantage and one disadvantage for the genetic testing and/or gene editing
CRISPR - treating genetic disorders, sustainable farming
Advantage:
What is the difference between a point mutation and frameshift mutation at the DNA level? Which usually has a larger effect on the protei? Explain the effect
Point mutation - singular nucleotide is changed/substituted
Frameshift mutation - nucleotide is inserted or deleted, shifts the reading frame of the entire sequence
Frameshift has a larger impact than point mutations because they shift the way the genetic code is read and shift every amino acid after the mutation