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sites that are free of any microbes are called
axenic
what locations of the body should be axenic
alveoli, CNS, circulatory system, upper urogenital regions, uterus
the habitat in which an organism normally lives, grown, and multiplies is known as the
reservoir
what are two diseases humans can give animals
MRSA and Influenza A
reservoir for anthrax
outside animal
3 major portals of entry
skin, mucous membranes, placenta
what is the most common site of entry
respiratory tract
what are some diseases that can result from pathogens crossing the placenta
toxoplasmosis
syphilis
listeriosis
erythema infectiosum
AIDS
german measles
____ microbia live with us while __ microbia are picked up from the environment
resident, transient
opportunistic pathogens are normal microbiota that cause ___ under certain conditions
disease
what are the 3 types of reservoirs
animal, human, nonliving
diseases naturally spread from animal to humans are called
zoonoses
reservoir for malaria and yellow fever
primates
reservoir for toxoplasmosis
cat
reservoir for bubonic plague
rodents
isolation restricts movement of ____ people while quarantine restricts movement of ____ people
ill, well
t/f
infection may or may not result in disease
true
what is not considered a true portal of entry but provides a way for the pathogen to enter the body by being deposited directly into the tissue
parenteral route
symptoms are ____ and felt while signs are ____ and measured
subjective, objective
the degree of pathogenicity or how easy it is for the organism to cause disease is known as
virulence
an inanimate object involved in indirect transmission
fomite
what are the 3 modes of transmission
contact, vehicle, vector
mechanical vectors ___ the pathogen and biological vectors are the ____ for pathogens
carry, host
incidence refers to the number of ___ cases and prevalence refers to the number of ____ cases
new, total
the case fatality rate is the number of ___ divided by the number of ___
fatalities, confirmed cases
crude mortality rate is the number of ___ divided by the _____
fatalities, total population
disease that typically occurs at regular intervals at a stable incidence within a given population or area
endemic
only a few scattered cases within an area or population
sporadic
occurs at greater frequency than is usual
epidemic
an epidemic that occurs simultaneously on more than one continent
pandemic
what is the index case
first case of the disease
what are nosocomial infections
healthcare associated infections
who is the father of modern microbiology? what theory did he make
louis pasteur
germ theory of disease
who discovered handwashing was important after figuring out why women were dying during child labor from puerperal fever
semmelweis
who discovered antiseptic technique
lister
who worked on infection control of cholera
snow
who developed smallpox vaccine
jenner
mycobacteria are gram ___ and mycoplasma are gram ___
+, -
what color do gram + appear after stain
purple
acid-fast bacteria/mycobacteria contain what
waxy, mycolic acid
staining increases ___ and ____ by coloring specimens
contrast, resolution
what color do acid-fast cells stain? what color do non-acid-fast cells stain?
red, blue
what color do endospores stain? what color do vegetative cells stain?
green, magenta
series of paired statement where only one or two either/or choices apply are known as
dichotomous/taxonomic keys
a ______ is an aggregation of cells arising from a single parent cell and a ___ is a collection of microbes in a complex community
colony, biofilm
photoautotrophs use ___ for energy and ___ for carbon source
light, co2
chemoautotrophs use ___ for energy and ___ for carbon source
chemical compounds, co2
photoheterotrophs use ___ for energy and ___ for carbon source
light, organic compounds
chemoheterotrophs use ____ for energy and ___ for carbon source
chemical compounds, organic compounds
what is required for growth
oxygen, pH, temp, moisture, osmotic pressure, light, food
what is the most important factor which affects growth of microorganisms
temperature
___ prefer cold temps
____ prefer mild temp
___ prefer high temp
psychrophilic
mesophilic
hyper thermophilic
what media are fungi selective towards
sabouraud dextrose sugar
what helps differentiate streptococcus organisms
blood agar
what media is selective for gram - bacteria but also differentiates between the types of gram -
MacConkey Agar
types of plasmids:
fertility factors carry instructions for ____
resistance factors carry genes for ___ to antibodies
bacteriocin factors carry genes for toxins called ____
virulence factors carry instructions that enable bacterium to become ____
conjugation
resistance
bacteriocins
pathogenic
organisms replicate their genomes and provide copies to descendants...this is normal in both eukaryotes and prokaryotes
vertical gene transfer
acquiring genes from other microbes of the same generations, donor cell contributes part of genome to recipient cell...only prokaryotes
horizontal gene transfer
what are the 3 types of horizontal gene transfer
transformation, transduction, bacterial conjugation
transformation involves the recipient cell taking up DNA from the ___ and it becomes known as ___
environment, competent
transduction involves the transfer of DNA from one cell to another via a _____
replicating virus
conjugation involves transfer of DNA from one cell to another via conjugation pili, what does the donor cell require and what does the recipient cell lack
F plasmid