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Step 1 enzyme
Hexokinase: phosphorylates glucose
Glucose to G6P with use of ATP
Step 1 logic
increase energy of molecule by providing grip through phosphorylation, more induced fit
No G6P transporter = trapped glucose inside of cell
Step 2 enzyme
phsphoglucoseisomerase: makes isomer of G6P
G6P to G6P
Step 2 logic
establishes molecular symmetry for step 4, break into equal pieces
another terminal OH
Step 3 enzyme
phosphofructokinase: phosphorylate F6P
Step 3 logic
increase energy and provide grip catalyzes one of rate-d determining reaction
Step 4 enzyme
Aldolase: cleavage of FBF to GAP and DHAP
Step 4
divides glycolytic pathway into two parallel 3-carbon pathway allowing cell to harvest twice as much energy per glucose molecule
Step 5 enzyme
Trios phosphateisomerase: isomerize DHAP → GAP (ketone to aldehyde)
Step 5 logic
ketone sucks
covert to GAP which is an aldehyde