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Natural Selection
Process where organisms with favorable traits are more likely to survive and reproduce.
Overproduction
Organisms produce more offspring than can survive.
Competition
Individuals compete for limited resources.
Variation
Differences in traits occur naturally and are heritable.
Adaptation
Accumulation of favored traits in a population over time.
Biological fitness
An individual's ability to survive and reproduce successfully.
Fossils
Evidence of past life, confirming existence of extinct species.
Molecular evidence
Similar DNA, amino acids, triplet codes, enzymes, ATP, etc.
Analogous structures
Same function, different structure.
Homologous structures
Same structure, different function.
Vestigial structures
Structures that are no longer in use.
Directional selection
One extreme phenotype is more fit.
Stabilizing selection
Intermediate phenotypes more fit than extreme ones.
Disruptive selection
Both extreme phenotypes more fit.
Sexual selection
Selection based on the ability to attract a mate.
Genetic drift
Allele frequencies change over time due to random chance.
Bottleneck effect
Population is reduced rapidly, typically affecting small populations.
Founder effect
Small portion of population migrates to a different area.
Gene flow
When an individual moves, they bring their genes with them.
Allopatric Speciation
Isolation is due to a physical geographical barrier separating individuals.
Sympatric Speciation
Individuals have the potential to be in the same place at the same time but don't interbreed.
Helicase
Unwinds/unzips the double strand of DNA.
Topoisomerase
Relieves strain ahead of the replication fork by breaking, swiveling, and rejoining DNA strands.
Single Strand Binding protein
Stabilizes unwound DNA strands, preventing rebonding.
Primase
Sets RNA primers on the DNA template.
DNA pol III
Adds nucleotides to the 3' end of a DNA strand.
DNA Pol I
Removes RNA primers and replaces them with DNA nucleotides.
Ligase
Ties sugar-phosphate backbone together.
Nuclease
Removes any mistake nucleotides.
RNA splicing
Spliceosomes remove introns and connect exons.
RNA polymerase
Binds to promoter and separates DNA strands during transcription.
Repressors
Bind to operators, reducing transcription.
Activators
Increase transcription of operon.
Inducible Operon
Usually off but can be turned on.
Repressible operon
Usually on but can be turned off.
LAC Operon
Builds lactose, inducible operon.
Enhancer
Increases probability of transcription (DNA-bending).
Micro RNAs (miRNAs)
Short segments of RNA that can either burst apart mRNA or block translation.
Point mutation
Substitution of one base for another.
Frameshift mutation
Adding or removing a nucleotide, shifts everything after.
Silent mutation
No change in amino acid.
Missense mutation
Mutation that leads to a different amino acid.
Nonsense mutation
Occurs when a stop codon appears where it shouldn’t.
Polymerase Chain Reaction (PCR)
Produces many copies of a target template DNA sequence.
Gel electrophoresis
Separates DNA fragments based on their size.
DNA cloning:
Makes many copies of a DNA fragment of interest.
Enzymes
Speeds up chemical reactions.
Induced fit
Enzyme changes shape slightly when it binds to its substrate.
Competitive Inhibition
Decreases reaction rate when there are less substrates.
Noncompetitive inhibition
Enzymatic reaction will never reach its max rate regardless of available substrate.
Glycolysis
Glucose broken down into 3 carbon molecules in the cytoplasm.
Krebs cycle
Occurs in mitochondrial matrix, producing ATP, NADH, and FADH2.
Oxidative phosphorylation
ETC in inner mem of mitochondria, lowers free energy in small amounts.
Fermentation
Occurs in cytoplasm, anaerobic pathway for breaking down glucose when oxygen is used up, creating few ATP.
light-dependent reactions
Takes place in thylakoid membrane.
Calvin cycle
Carbon fixation in the stroma, uses ATP and NADPH to convert CO2 into sugar.
Entropy
Measure of molecular disorder.
1st law of thermodynamics
Energy can't be created nor destroyed, only transformed.
2nd law of thermodynamics
Energy transformations increase entropy of universe.
Apoptosis
Programmed cell death
G1 checkpoint
Primary checkpoint in which cells decides to divide, check cell size, nutrients, growth factors, and DNA damage
G2 checkpoint
Make sure division goes smoothie, check DNA damage + DNA replication completeness
Ligands
Molecules that bind specifically to other molecules, receptors
Autocrine
cell signals itself, ligand binds to receptor on its own surface
Paracrine
Cell communicates over relatively short distances
Endocrine
uses circulatory system as a distribution network
Synaptic
nerve cells transmit signals
Innate Behaviors
Predicted and performed similarly across members of same species
Learned Behaviors
Animals, mainly primates, capable of problem-solving & construction of mental maps
Exponential growth
populations growth rate stays the same regardless of population size, J shaped curve
Logistic growth
populations growth gets smaller as population size approaches carrying capacity, S-shaped curve
Cyclical oscillations
repeated rise and drops in size of population over time
Carrying capacity
maximum number of individuals an ecosystem can support
Competition
(-/-) species compete when they have overlapping niches
Predation
(+/-) one species, predator, kills and eats individual of other species, prey
Mutualism
(+/+) both interacting species benefit
Commensalism
(+/0) benefits individuals of one species without harming or helping individuals of the other species
Parasitism
(+/-) parasite gains something while the host loses something
Invasive species
species that have been introduced to areas outside of the native range, they may outcompete native species for resources, altering community structure
Keystone species
often predators and they hold a community together and keep other species stable. Removal of keystone species can drastically impact other species
Prokaryotes
Dna is circular, free floating in cytoplasm, No nucleus + membrane bound organelles, Small (1-5 micrometers), Always unicellular, ex: bacteria, archaea
Eukaryotes
Dna is linear, found in the nucleus, Has nucleus & membrane bound organelles, Larger (10-100 micromolecules), Can be unicellular or multicellular, ex: animals, plants, fungi, protists
Endosymbiotic theory
how eukaryotic cells evolved from prokaryotic cells
phospholipid bilayer
amphiphilic nature, polar hydrophilic head + non polar hydrophobic tail, creates basic structure of the membrane + acts as barrier to most water soluble molecules
Integral proteins
embedded in phospholipid bilayer & extend all the way across the membrane, contains at least one hydrophobic region that anchors them to core of bilayer
Passive transport
transport that doesn't require energy
Active transport
transport the required input of energy to occur
Endocytosis
term for various types of active transport that moves particles into cell by enclosing them in a vesicle made of plasma membrane
Exocytosis
form of bulk transport where materials are transported outside of cell in membrane bound vesicles that fuse with plasma membrane
Hypotonic
solute concentration is lower than cell concentration, net flow of water INTO cell, cell gains volume
Isotonic
solute concentration same as cell, no net nonevent of water into or out of cell, volume remains the same
Hypertonic
greater solute concentration than cell, net movement of water OUT of cell, cell loses volume
Meiosis
The specialized type of cell division that reduces the chromosome number by half, resulting in four haploid cells
Mendel’s laws
Law of Segregation AND Independent assortment
Law of Segregation
During meiosis the alleles for a trait separate, so each gamete only gets one allele
Independent assortment
During meiosis, alleles for one trait separate independently from other pairs of alleles, allowing for all possible combinations
Non-Mendelian inheritance
Codominance, Incomplete dominance, Pleiotropy, Epistasis, Multiple alleles, Sex-linked, Polygenic Inheritance, Linked genes
Codominance
both alleles/phenotypes are being expressed
Incomplete dominance
Heterozygous genotype, shows a blend of traits
Pleiotropy
single gene contributes to multiple characteristics