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cardiovascular system
a closed circulatory system
cardiovascular system includes
heart, blood vessels, and blood
cadiovascualry system functions
transports gas, nutrients, and waste throughout the body, prevents loss of blood via ruptured vessels, fights invasion from foreign pathogens
Heart
fist sized, cone shaped muscular organ, a double pump because of two circuits
the heart has
four chambers and one way valves
pericardial cavity
location of the heart, in the anterior portion between the lungs
mediastinum
the space between the lungs, contains the heart
pleural cavities
two spaces, each holding a lung
pericardium
a tough, thick sac holding the heart, protects and anchors the heart to the diaphragm
pericardium layers
covered with a smooth layer of endothelium, fluid between the layers to reduce friction
myocardium
the bulk of the heart, composed of cardiac muscle and contracts, highly branched and attached with collagen connective tissue fibers
endocardium
a white sheet of endothelium, is continuous with blood vessel linings
septum
separates the heart into left and right chamber sets
fossa ovalis
a shallow depression separating the atria, marks an opening on babies in womb for blood flow, but closes during birth
atria
the two upper receiving chambers, smaller and not as muscular
ventricles
the two lower pumping chambers
pulmonary valve
controls the flow leaving the right ventricle to the pulmonary trunk, pumps into the pulmonary arteries to the lungs
aortic valve
controls the flow of blood out of the left ventricle into the aorta, stronger than the pulmonary valve due to increased blood pressure
mitral valve
(bicuspid) controls the flow of blood from the left atrium to the left ventricle
tricuspid valve
controls the flow of blood from the right atrium to the right ventricle
arteries
carry blood away from the heart, have pulses, elastic, thick walled vessels that can expand and contract
arterioles
small arteries that are constricted and dilated by muscles, contraction increases blood pressure, relaxation decreases blood pressure
peripheral resistance
varying blood pressure, commonly caused by arterioles
veins
carry blood back to the heart, thinner walled vessels under minimal pressure, no pulse
veins valves
internal valves that open toward the heart and close at the end of a heartbeat
veins stretch
has compliance, stretch with little recoil, leading to the largest amount of blood
lumen
the opening in the center of a vessel
tunica externa
most superficial layer of a vessel, anchors the vessel to surrounding structures
tunica media
middle muscular layer of a vessel,
tunica media layers
an external elastic membrane, smooth muscle, and internal elastic membrane
tunica intima
inner layer of a vessel
tunica intimate layers
subendothelial tissue and endothelium
capillaries
exchange materials with tissues, very narrow from branching of the arterioles, slow even flow to allow for oxygen and waste diffusion
capillary beds
interconnected capillaries to exchange materials with cells
venules
small veins that collect blood from the capillary beds, many join to form a vein that returns blood to the heart
left coronary artery
runs towards the left side of the heart
left coronary artery splitting
anterior interventricular branch and the circumflex branch
anterior interventricular branch
supplies blood to both ventricles
circumflex branch
supplies the left atrium and left ventricle
right coronary artery
runs towards the right side of the heart, supply the right atrium and right ventricle
right coronary artery splitting
posterior interventricular artery and the marginal artery
aortic arch
turns posteriorly to become the descending aorta
thoracic aorta
in the thoracic cavity above the diaphragm
abdominal aorta
the descending aorta after the diaphragm
inferior vena cava
returns deoxygenated blood from the lower body to the right atrium
superior vena cava
returns deoxygenated blood from the upper body to the right atrium
brachiocephalic trunk
first branch off the aortic arch, supplies blood to the right arm and neck
circle of Willis
AKA cerebral arterial circle, provides an alternative circulation if an artery gets blocked
blood
classified as a connective tissue
plasma
the liquid portion, buffers the pH of the blood near 7.4, transports large organic molecules in blood, and clots
plasma and pressure
maintains the bloods osmotic pressure due to protein presence
osmotic pressure
the net pressure in the blood that moves fluid from the tissues into the circulatory system
hydrostatic pressure
pushes fluid into the tissues by the pressure of the blood pumping from the heart
formed elements
the cell portion of blood, consists of red blood cells, white blood cells, and platelets
Serum
identical to plasma, but with the clotting proteins removed, centrifuged after clotting
red blood cells
small biconcave disks that carry oxygen, most abundant cell, contains about 250 million hemoglobin molecules
red blood cell manufacturing
continuously in red bone marrow of the skull, ribs, vertebrae, and long bone ends
red blood cell life
mature red blood cells are anucleate when released, have a lifespan of 120 days then are destroyed in the liver and spleen
hemoglobin
contains iron to combine loosely with oxygen to help carry oxygen, is recycled when red blood cells are destroyed
white blood cells
AKA leukocytes, larger with a larger nucleus, and lack hemoglobin, destroy foreign materials at injury sites
pus
contains many dead white blood cells that have fought the infection
granulocytes
have granules in the cytoplasm, include neutrophils, eosinophils, and basophils
agranulocytes
do not have granules in the cytoplasm
lymphocytes
include T
blood platelets
involved in coagulation (blood clotting) to stop bleeding, fragments of megakaryocytes
megakaryocyte
large bone marrow predecessor
coagulation cascade
a series of events to start the blood clotting mechanism, when platelets release chemicals
prothrombin activator
converts prothrombin to thrombin, released by platelets and injured tissues
fibrinogen
a protein manufactured by the liver that freely floats in the blood, converted to fibrin by thrombin
fibrin
winds around the platelet plug to provide the framework for the clot
diastolic pressure
pressure in the arteries during ventricular diastole
sphygmomanometer
medical equipment that measures blood pressure, the amount of pressure required to stop the flow of blood through the brachial artery
heart rate
regulated by the nervous system and endocrine system
SA node
(sinoatrial node) small mass of cardiac muscle in the right atrium, controls the cardiac cycle and spreads impulses to the atria
AV node
(atrioventricular node) where the impulse travels after the atria
Bundle of His
receives the impulse from the AV node, then sends it to the ventricular apex
Purkinje fibers
receives the impulse from the ventricular apex and causes the left and right ventricles to contract
Electrocardiogram
EKG/ECG, measures the electrical impulses in the heart
P wave
Atrial depolarization and atrial systole
QRS complex
Ventricular depolarization and ventricular systole
T wave
Ventricular repolarization and ventricular diastole
Syncope
fainting as a result of a lack of blood flow to the brain from a drop in arterial blood pressure
edema
a buildup of fluid in the body, can be caused by heart failure