Anti-Alzheimer's Disease

Alzheimer's Disease (AD)

Characterized by degeneration of cholinergic neurons leading to deficiencies in acetylcholine (ACh).

Acetylcholinesterase (AChE) inhibitors

Medications used to treat Alzheimer's Disease by inhibiting the breakdown of ACh, thereby increasing ACh levels in neuron receptors.

Cognitive function improvement with AChE inhibitors

AChE inhibitors increase cognitive function for patients with mild to moderate Alzheimer's Disease.

Reversible AChE inhibitors

A category of AChE inhibitors that temporarily inhibit the enzyme's activity.

Nonreversible AChE inhibitors

A category of AChE inhibitors that permanently inhibit the enzyme's activity.

Rivastigmine

An AChE inhibitor used for mild to moderate Alzheimer's Disease; absorbs faster through the gastrointestinal tract without food.

Contraindications for Rivastigmine

Rivastigmine is contraindicated in patients with liver and renal dysfunction.

Nursing considerations for Rivastigmine administration

Monitor patients for gastrointestinal symptoms such as nausea and vomiting, which are common side effects.

Dosage adjustments for Rivastigmine

Adjustments may be necessary for elderly patients or those with hepatic impairment due to the increased risk of side effects.

Patient education regarding Rivastigmine

Instruct patients and caregivers to take Rivastigmine with food to reduce gastrointestinal side effects.

Signs of Rivastigmine toxicity

Watch for symptoms such as severe nausea, vomiting, diarrhea, or muscle twitching, which may indicate overdose.