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1453
Ottomans capture Constantinople, leading to the fall of the Byzantine Empire.
1450s
Gutenberg Printing Press is introduced in Europe.
c. 1480s
The height of the Aztec Empire occurs.
1488
Dias rounds the Cape of Good Hope.
1492
Columbus discovers the Americas; the Reconquista of Spain is completed.
1502
The first African slaves arrive in the Americas.
1517
Martin Luther leads the Protestant Reformation.
1521
Cortez conquers the Aztec Empire.
1526
The Mughal Empire in India begins.
1529
The first unsuccessful Ottoman siege of Vienna occurs under Suleiman.
1533
Pizarro topples the Inca Empire.
1543
Copernicus proposes the heliocentric model, marking the beginning of the Scientific Revolution.
1545
Discovery of silver at Potosi takes place.
1571
The Battle of Lepanto results in an Ottoman naval defeat by a European coalition.
1571
The first Manila Galleon establishes global trade.
1588
The Spanish Armada is defeated.
1600
The Battle of Sekigahara marks the beginning of the Tokugawa Shogunate in Japan.
1607
Jamestown, Virginia, is founded.
1618-1648
The Thirty Years' War takes place in Europe.
1644
The end of the Ming dynasty and the beginning of the Qing dynasty occurs.
1653
The Cape Town colony is founded by the Dutch.
1683
The second unsuccessful Ottoman siege of Vienna takes place under Mehmet IV.
1689
The Glorious Revolution leads to the English Bill of Rights.