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cervical cancer
low-income countries, linked to genital infection with HPV, a sexually transmitted disease, mostly 16-18 year olds
cervical cancer prevention
HPV vaccine, primary prevention: 10-14 girls, secondary prevention: Pap smear, HPV tests, tertiary prevention: diagnosis and treatment of invasive cervical cancer and palliative care
WHOs global strategy to accelerate the elimination of cervical cancer as a public health problem
90-70-90 targets to be met by 2030, 90 percent girls vaccinated with HPV by 15, 70 percent women screened with high performance test by 35 and agin by 45 , 90 percent women identified with cervical disease receive treatment
benefits of 90-70-90 targets
low and lower middle income countries, fall of cervical cancer incidence rate and deaths
cervical cancer and HIV
link between HIV and cervical cancer is direct and deadly
A low cost screening method
visual inspection with acetic acid through screening, soaking the cervix for about 5 minutes with regular vinegar
digital cervicography advantages
photos can be saved and reviewed by physicians, can be remotely viewed for real-time physician consultation
recent shift in WHO’s strategy towards HPV testing
encourages countries to use HPV tests for cervical screening, HPV-DNA detects high-risk strains of HPV, HPV mRNA detects infections that lead to cellular transformation, HPV testing is objective as it does not rely on visual inspection and is more cost-effective than pap smears
see and treat approaches
can be done by trained nurses cervicography is accurate and can be sent to an expert anywhere in the world who can assist in real time, screening must be linked to treatment and management of positive screening tests
how does cryotherapy work?
apply probe to cervix for a 30 second freeze and let defrost, repeat one time, not too painful and cheap
HPV vaccine
safe and effective in girls not yet exposed, protects against HPV 16 and 18, protects for at least 8 years but likely much longer
HPV vaccine in kenya
lack of awareness and knowledge, fear of side effects, religion, misinformation, communications with health workers, limited health resources, corruption, cost and need for 3 doses
breast cancer
self breast exams, clinical examination, mammography