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Explain the difference between an observational study and an experiment
In an observational study, researchers don't assign choices. Experiment, they randomly assign choices
Explain the differences between experimental units and subjects
Subjects- Humans
Experimental Units-More generic (other indvs. such as rats, days)
Why is it necessary to assign subjects to treatments at random
To be able to justify relationships
Describe the four Principles of Experimental Design
Control - Making conditions as similar as possible for all treatment groups
Randomization - Allows to equalize effects of unknown or uncontrollable sources of variation
Replication - Apply treatment to number of subjects
-Only with replication can estimate variability of responses
Blocking - Ability of randomizing to equalize variation across treatment groups
Explain what is meant by a control group
What groups are compared to. What group is receiving control treatment.
Define Statistically significant
big enough (significant enough) difference between results of data groups
What is the purpose of using a single-blind or double-blind experiment
To avoid bias
What is a placebo? What is meant by the placebo effect?
Placebo- A "fake" treatment that looks just like treatments being tested
Placebo effect- Highlights importance of effective blinding and importance of comparing treatments with a control
What is the purpose of using blocking in an experiment
Isolate variability attributable to differences between the blocks, so you can see the differences between blocks.
How might confounding affect the results of an experiment
Can't tell whether any effect we see was caused by our factor or confounding variable, or both working together.
observational study
researchers don't assign choices, simply observe them
retrospective study
researchers identify subjects and collect data
prospective study
identify subjects in advance and collecting data as events unfold
experiment
manipulate factor levels, randomly assign subjects to treatment levels, compare responses of groups
random assignment
needed for experiments to justify claims
subjects
humans being experimented on
participants
humans being experimented on
experimental units
generic term of other indvs. (rats, bacteria)
factors
explanatory variable to manipulate
levels
specific values that the experimenter chooses for a factor
treatment
combo of specific levels from all the factors that an experimental unit recieves
block
ability of randomizing to equalize variation across treatment groups work best in the long run
completely randomized experiment
subjects randomly assigned treatment
statistically significant
big difference between results of treatment groups
control
making conditions as similar as possible for all treatment groups
control group
what group is receiving control treatment (comparison)
single blind
when indvs. of one group that can effect outcome is blinded
double blind
when both groups are blinded
placebo
"fake" treatment that looks just like treatments being used
placebo effect
highlights importance of effective blinding and importance of comparing treatments with control
matching
compare treated and non treated in observational study
confounding
levels of 1 factor associated with levels of another factors