Beta Blockers Calcium Channel Blockers and Diuretics

Labetalol

Brand: Normodyne | Class: Beta Blocker | Uses: Hypertension

Carvedilol

Brand: Coreg | Class: Beta Blocker | Uses: Hypertension; Heart failure

Nebivolol

Brand: Bystolic | Class: Beta Blocker | Uses: Hypertension

Propranolol

Brand: Inderal | Class: Beta Blocker | Uses: Hypertension; Angina; Migraine

Atenolol

Brand: Tenormin | Class: Beta Blocker | Uses: Hypertension; Angina

Metoprolol tartrate / succinate

Brand: Lopressor / Toprol-XL | Class: Beta Blocker | Uses: Hypertension; Heart failure

Diltiazem

Brand: Cardizem | Class: Non-DHP CCB (Calcium Channel Blocker) | Uses: Hypertension; Rate control

Verapamil

Brand: Calan; Verelan | Class: Non-DHP CCB (Calcium Channel Blocker) | Uses: Hypertension; Rate control

Amlodipine

Brand: Norvasc | Class: DHP CCB (Calcium Channel Blocker) | Uses: Hypertension

Nifedipine

Brand: Procardia | Class: DHP CCB (Calcium Channel Blocker) | Uses: Hypertension

Nicardipine

Brand: Cardene IV | Class: DHP CCB (Calcium Channel Blocker) | Uses: Hypertension

Felodipine

Brand: Plendil | Class: DHP CCB (Calcium Channel Blocker) | Uses: Hypertension

Nisoldipine

Brand: Sular | Class: DHP CCB (Calcium Channel Blocker) | Uses: Hypertension

Triamterene / HCTZ

Brand: Dyazide; Maxzide | Class: K-sparing + Thiazide | Uses: Hypertension

Furosemide

Brand: Lasix | Class: Loop diuretic | Uses: Edema

Bumetanide

Brand: Bumex | Class: Loop diuretic | Uses: Edema

Torsemide

Brand: Demadex | Class: Loop diuretic | Uses: Edema

Spironolactone

Brand: Aldactone | Class: K-sparing + Aldosterone antagonist | Uses: Heart failure

Hydrochlorothiazide

Brand: Microzide | Class: Thiazide | Uses: Hypertension

Chlorthalidone

Brand: Thalitone | Class: Thiazide-like | Uses: Hypertension

Normodyne

Generic: Labetalol

Coreg

Generic: Carvedilol

Bystolic

Generic: Nebivolol

Inderal

Generic: Propranolol

Tenormin

Generic: Atenolol

Lopressor / Toprol-XL

Generic: Metoprolol tartrate / succinate

Cardizem

Generic: Diltiazem

Calan / Verelan

Generic: Verapamil

Norvasc

Generic: Amlodipine

Procardia

Generic: Nifedipine

Cardene IV

Generic: Nicardipine

Plendil

Generic: Felodipine

Sular

Generic: Nisoldipine

Dyazide / Maxzide

Generic: Triamterene / HCTZ

Lasix

Generic: Furosemide

Bumex

Generic: Bumetanide

Demadex

Generic: Torsemide

Aldactone

Generic: Spironolactone

Microzide

Generic: Hydrochlorothiazide

Thalitone

Generic: Chlorthalidone

Beta Blockers - Mechanism / Rationale

Decrease heart rate and blood pressure

CCBs (Calcium Channel Blockers) - Mechanism / Rationale

Non-DHP (heart-rate slowing) vs DHP (vasodilation)

Diuretics - Mechanism / Rationale

Lower blood pressure and increase urine output

Beta Blockers - Common Side Effects

Fatigue; bradycardia (slow heart rate)

Non-DHP CCBs - Common Side Effects

Bradycardia (slow heart rate)

DHP CCBs - Common Side Effects

Peripheral edema (swelling)

Loop / Thiazide Diuretics - Common Side Effects

Hypokalemia (low potassium); polyuria (frequent urination)

Potassium-sparing Diuretics - Common Side Effects

Hyperkalemia (high potassium)

Beta Blockers - Serious / Black-Box Risks

Abrupt discontinuation causes rebound ischemia / myocardial infarction (heart attack); severe heart block

Verapamil / Diltiazem (Non-DHP CCBs) - Serious / Black-Box Risks

Heart block in combination with other rate-slowing agents (beta blockers)

Loop Diuretics - Serious / Black-Box Risks

Profound diuresis and dehydration

Beta Blockers + Non-DHP CCBs or Digoxin - High-Yield Interactions

Bradycardia (slow heart rate) / heart block

Beta Blockers in Diabetic Patients - High-Yield Warning

Can mask hypoglycemia symptoms in diabetics on insulin

Potassium-sparing Diuretics + ACE Inhibitors / ARBs / NSAIDs - High-Yield Interactions

Hyperkalemia (high potassium)

Beta Blockers & Non-DHP CCBs - Absolute Contraindications

Heart block

Diuretics - Absolute Contraindications

Anuria (inability to produce urine)

Some Beta Blockers - Absolute Contraindications

Severe asthma