MOD 6: QC/QA - 10

Flame Emission Spectrophotometry

A type of flame spectroscopy used to detect metals from groups IA and IIa

Atomic Absorption Spectrophotometry

A type of flame spectroscopy used for the quantitative determination of most of the elements in multivitamins and mineral formulations, drugs and BIOLOGICAL fluids

Turbidimetry

Spectrosphotometric technique used for the Assay of Vitamin B12, Antibiotics, and Ca pantothenate

Fluorescence spectrometry

Spectrophotometric technique used for the analysis of vitamin B1 and B2

Infrared spectroscopy

Type of spectroscopy associated with vibrational transitions of atoms within molecules

Stretching

Type of fundamental vibrations wherein the distance increases or decreases ALONG the bond axis

Bending (or Deformation)

Type of fundamental vibrations wherein there is change in BOND ANGLES

Rocking and Scissoring

In-Plane Bending (2)

Wagging and Twisting

Out-of-plane Bending (2)

3-8 um

Wavelength range of the group frequency region of Medium IR; absoprtion peaks due to functional groups found in organic compounds

8-15 um

Wavelength range of Fingerprint Region of Medium IR; Gives a spectrum of the whole molecule for its identification

Nuclear magnetic resonance

Spectrophotometric technique mainly for structure elucidation

Charcoal

Strongest adsorbent for column chromatography

Sucrose

Weakest adsorbent for colum chomatography

Column

The heart of HPLC

HPLC

Most widely used technique in drug analysis

Gas Chromatography

Chromatography for the analysis of volatile samples

Voltametry

Study of voltage-current-time relationships during electrolysis carried out in a cell

Polarography

Analysis based on the measurement of current resulting from the electrolysis of an electroactive species at a given electrode potential under controlled conditions