HLTH 201: Ch. 9B - Cell Proliferation, Tissue Regeneration, and Repair

What is cell proliferation?

cell division

What is cell differentiation?

The process in which cells become specialized.

what occurs during healing with connective tissue repair?

damaged area is being filled with connective tissue

what are the phases of repair by connective tissue?

1. hemostasis to form connective tissue
2. emigration of fibroblasts to lay down connective tissue
3. maturation of scar tissue

What is granulation tissue?

red, vascular, newly formed capillaries

what are the types of cutaneous wound healing?

primary intention, secondary intention, delayed primary intention

What is healing by primary intention?

wound edges are closer to one another causing minimal scarring

What is healing by secondary intention?

wound edges are farther apart causing larger scars to form

what is healing by delayed primary intention?

wound that needs to be irrigated and then sutured

which type of cutaneous healing causes minimal scarring?

primary intention

which type of cutaneous healing causes larger scarring?

secondary intention

what type of cutaneous wound healing is this?

primary intention

what type of cutaneous wound healing is this?

secondary intention

what are the phases of cutaneous healing?

1. inflammatory phase
2. proliferative phase
3. remodeling phase

when does the inflammatory phase of cutaneous healing start?

right after the injury

what occurs during the inflammatory phase of cutaneous healing?

hemostasis (clot formation), vascular phase, cellular phase

what occurs during the proliferative phase of cutaneous healing?

build up of new tissue to fill in the wounded space

what occurs during the remodeling phase of cutaneous healing?

strength of wound increases

what is simple resolution wound healing?

no destruction of normal tissue so damaged tissue recovers and function returns to normal

what is regenerative wound healing?

replacing necrotic tissue with tissue that is structurally and functionally identical

what is repair by scar tissue?

damaged cells are replaced by connective tissue so function is lost

what are common complications that can occur when healing by scar formation?

contractures, adhesions, hypertrophic scar tissue, keloids

What is a contracture of a scar?

healing causes scar to become smaller than the wound and causes limited movement

what is adhesions of a scar?

scar tissue binds different organs together

what is a hypertrophic scar?

Excess production of scar tissue that is localized to the wound

What is a keloid?

excessive scar growth that is outside the boundaries of the wound

what type of scar formation is this?

contracture

what type of scar formation is this?

adhesions

what type of scar formation is this?

hypertrophic scar

what type of scar formation is this?

keloid

why is adequate hemoglobin important for tissue healing?

oxygen is needed for tissue healing

why do patients with anemia have delayed tissue healing time?

not enough oxygen to heal tissue

why are elderly patients more vulnerable to chronic wounds?

decreased dermal thickness, collagen content, and elasticity