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Psychological Disorder
Behavioral, psychological, or biological dysfunctions that are unexpected in their cultural context and associated with present distress and/or impairment in functioning, or increased risk of suffering, death, pain, or impairment
3 Criteria of Psychopathology
· Psychological dysfunction – breakdown in cognitive, emotional, or behavioral functioning
· Distress/impairment: causes problems in social, occupational, or other important activities
· Atypical or not culturally expected response: violating social norms
· Consider "normalcy" relative to the behavior of others in the same cultural context
Clinical description
The process of assessing a client’s mental health through testing and observation
Components of clinical description
Presenting problem
Prevalence
Incidence
Course
Onset
Prognosis
3 Prominent historical approaches
Supernatural, biological, psychological
Supernatural
· Abnormal behavior believed to be caused by demonic possession, witchcraft and sorcery; treatments included exorcism, torture, and religious rituals
· Mass hysteria evidence of demonic possession (Saint Vitus’s Dance/Tarantism) – emotion contagion; mob psychology
· Insanity caused by emotional stress, not supernatural forces; treatments: rest, sleep, healthy environment, baths, potions
· Paracelsus (Swiss physician): mental health problems are affected by the pull of the moon and stars – led to term “lunatic”
Biological
· Hippocrates Humoral Theory of Disorders: Four key bodily fluids (humors) – disease caused by having too little or too much
o Blood, phlegm, black bile, yellow bile
o Ex. depression caused by too much black bile
o Treatment: changing environmental conditions or bloodletting/vomiting
· General paresis (late-stage syphilis) – caused by bacterium
o Symptoms similar to psychosis – bolstered view that mental illness = physical illness
· John P. Grey and the reformers – mental illness has physical roots
o Treatment for mentally ill same as physically ill
o Led to reforms of hospitals to give psychiatric patients better care – became too big patients weren’t given proper care
· Treatments: insulin shock therapy, electroconvulsive therapy (ECT) – Ben Franklin, medication – neuroleptics (major tranquilizers now called antipsychotics) and minor tranquilizers prescribed for anxiety disorders
Psychological
Moral therapy – treated institutionalized patients as normally as possible in a setting that encouraged and reinforced normal social interaction
Declined in use due to
Size and composition of institutionalized population (many after civil war + immigrants) works best with smaller number of ppl
Dorothea Dix and mental hygiene movement – focused on providing care to everyone who needed it – influx of patients
Mental illness believed to be incurable (caused by brain pathology – due to biological tradition)
Psychoanalytic Theory – Freud
Role of unconscious drives (such as sex and power) and importance of early life experience
Psychoanalytic therapy: reveal the nature of unconscious mental processes and conflicts
Free association, dream analysis, and analysis of transference
Little evidence of effectiveness
Psychodynamic therapy: more goal-oriented than psychoanalytic
Focuses on affect/expression of emotions, past experiences, etc.
Research shows may be effective for treating mental disorders
Cognitive-Behavioral Model
Combines insights from behavioral, cognitive, and social models – revolutionized the field by bringing about systematic development of more scientific approach to study of psychological disorders
Watson
Believes psychology is a purely objective experimental branch of natural science with goals of prediction and control of behavior
Multidimensional integrative approach
Interdisciplinary, eclectic and integrative system – abnormal behavior results from multiple influences: biological, behavioral, cognitive, emotional, social and cultural, developmental, and environmental
Genes
determine parts of physical and mental characteristics
Genotype
each pair of alleles
Single nucleotide polymorphisms (SNPs)
Variants of a single nucleotide
Two undeniable facts about psychopathology
Psychopathology is heritable: genes account for less than 50% of variations in psychopathology and all mental disorders are somewhat heritable
Development, behavior, and psychological disorders are almost always polygenic
Diathesis-stress model
· Individuals inherit tendencies to express traits/behaviors, which may then be activated under conditions of stress
· The greater the underlying vulnerability, the less stress is needed to trigger a disorder
· Low stressful environment, high genetic vulnerability = intermediate risk for developing mental disorder
· Low stressful environment, low genetic vulnerability = low risk for developing mental disorder
· High stressful environment, high genetic vulnerability = high risk for developing mental disorder
· High stressful environment, low genetic vulnerability = intermediate risk for developing mental disorder
Gene-environment correlation model
· People with a genetic predisposition for a disorder may also have a genetic tendency to create environmental risk factors that promote the disorder
· Genetics may make people more likely to seek out certain environments, thus affecting their experiences
Epigenetics
The study of factors other than inherited DNA sequences, such as new learning or stress, that alter the phenotypic expression of genes
Environmental influences (e.g. stress, nutrition) actually affect the expression of certain genes both for the individual and their descendants
Nongenomic "inheritance" of behavior: cross-fostering studies of development
Central nervous system
brain and spinal cord
Peripheral Nervous System
Autonomic nervous system and somatic nervous system
Autonomic nervous system
Sympathetic division and parasympathetic division – involuntary processes, regulates cardiovascular system/body temperature/endocrine system and aids in digestion
Somatic nervous system
controls voluntary muscles and movements
axon
trunk of neuron that sends messages to other neurons
Glutamate
Excitatory – “turns on” many different neurons, leading to action
GABA
o Inhibitory - regulate transmission of information
o Benzodiazepines used to treat anxiety
Norepinephrine
o Noradrenaline
o Part of endocrine system
o Involved in alarm responses and basic bodily processes (e.g. breathing)
Serotonin (5-HT)
o Inhibition and constraint
o Influences information processing, behavior, mood, and thoughts
o May contribute to depression
Dopamine
o Reward seeking and motivation
o Exploratory, outgoing, pleasure-seeking behaviors
forebrain
cortex and subcortex - where most of the study of psychopathology takes place
subcortex (below cortex)
thalamus and hypothalamus
thalamus
relay station of sensory information between brainstem and forebrain
hypothalamus
regulated endocrine system (HPA axis); maintains homeostasis
midbrain
coordinates movement with sensory input
hindbrain (brainstem)
regulates breathing, heart rate, digestion, etc. and includes medulla, pons, and cerebellum
frontal lobe
plans movements, recent memory, emotions
parietal lobe
receives and processes sensory input (touch, pressure, heat, cold, pain), perception of body awareness, constructs spatial “mental map” of our world
occipital lobe
visuospatial processing, distance and depth perception, object and face recognition
temporal lobe
processes auditory information, encodes memories, visual perception, language, emotion processing
prefrontal cortex
higher cognitive functions such as thinking, judgment, and reasoning, planning for the future, long-term memory
limbic system
· Part of the cortex – responsible for emotion, long-term memory, and behavior regulation
· Hippocampus: learning and forming new memories
· Amygdala: emotion (fear, anxiety, anger, pleasure); evaluating stimuli
· Basal Ganglia: movement and reward
· Cingulate Gyrus: emotion processing and behavior regulation
Hypothalamic-Pituitary-Adrenocortical (HPA) axis
· Exerts widespread effects on metabolism, immunity, and behavior, to help us cope with stress
· Stress results in the hypothalamus releasing the corticotropin releasing hormone (CRH) which stimulates anterior pituitary to release ACTH which causes adrenal glands to release cortisol (stress hormone)
cortico-limbic circuit
supports recognition, reactions, and threat-related processing; key regions are amygdala and prefrontal cortex – dysfunctions implicated in mood and anxiety disorders
cortico-striatal circuit
supports motivation, actions, and reward-related processing; key regions are basal ganglia and prefrontal cortex – dysfunctions implicated in mood, anxiety, eating, ADHD, substance use, and behavioral/impulse-control disorders
cortico-hippocampal circuit
supports memory and executive control; key regions are hippocampus and prefrontal cortex – dysfunctions implicated in schizophrenia, cognitive/memory impairments, and substance use, mood, and anxiety disorders
cognitive model
aaron beck and albert ellis
“You are what you think you are” – conscious thoughts influence our emotional and behavioral experiences; people create their problems by the way they cognitively interpret events and situations
beck’s cognitive theory
rational and maladaptive assumptions/thought processes can become habitual and automatic that influence our behaviors and feelings that lead to mental disorders
cognitive schemas, cognitive triads, cognitive distortions
cognitive triad
people have certain errors in their beliefs and these errors are relevant to three aspects: the self, the world, and the future
Involves individuals most likely prone to depression – they would have negative views of themselves (“I’m worthless and inadequate”) and negative views of the world around them (“Everyone is against me because I’m worthless”) and negative views of the future (“I’ll never be good at anything”) which would result in psychological disturbances especially relevant to depression
cognitive distortions
exaggerated thought patterns
All or nothing thinking, overgeneralizing, mental filter, disqualifying the positive, jumping to conclusions, and magnification/minimization
implicit processing
cognitive processes that occur outside conscious awareness or conscious control
nature of emotions
· pattern of action elicited by an external event and a feeling state, accompanied by a characteristic physiological response
o 6 primary emotions: happiness, sadness, fear, disgust, anger, surprise
primary functions of emotions
organize and motivate action; communicate information to others; provide us with information
3 components of emotion
physiology, emotion, cognitive
physiology - component of emotion
emotion is a brain function involving (generally) the more primitive brain areas; direct connection between these areas and the eyes may allow emotional processing to bypass the influence of higher cognitive processes
emotion/behavior - component of emotion
basic patterns of emotional behavior (freeze, escape, approach, attack) that differ in fundamental ways; means of communication
cognitive - component of emotion
appraisals, attributions, and other ways of processing the world around you that are fundamental to emotional experience (how we think about emotional experience)
cognitive/expressive suppression
try to hide or inhibit or suppress your emotional experience because you don’t want to think about or experience it
cognitive reappraisal
attempt to reinterpret some emotion/emotional situations that alters its meaning and emotional impact (thinking about positives rather than only negatives)
lifespan development
Prevalence and age of onset differs for mental disorders throughout development (ex. gender distribution in depression is approximately equal until puberty, when it becomes more common in girls
equifinality
a single outcome may have several causes
ex. people with PTSD can get it from different things (sexual assault, car accident, gun violence, etc.)
multifinality
a single cause may have several outcomes
ex. trauma can lead to no mental illness, PTSD, major depression disorder, substance-use disorder, etc.
3 key concepts in assessment
reliability, validity, standardization
clinical assessment
Systematic evaluation and measurement of psychological, biological, and social factors
mental status exam
· Brief preliminary test of a client's judgment, orientation to time and place, and emotional and mental state (typically done in an initial interview like the patient coming for the first time to seek treatment)
· Involves systematic observation of an individual's behavior and covers five categories: appearance and behavior; thought processes; mood and affect; intellectual functioning; and sensorium
thought processes
rate of speech, continuity of speech, content of speech
mood and affect
Predominant feeling state of the individual
Feeling state accompanying what individual says (does affect match what they are saying - such as laughing when talking about the death of a loved one would be mismatching affect)
intellectual functioning
type of vocab and use of abstractions and metaphors
physical exam
· Purpose is to rule out possible "organic cause" of psychological disorder
· Examples:
o Hypothyroidism -> depression and/or anxiety
o Brain tumor -> psychosis
o Cocaine withdrawal -> panic attacks
behavioral observation/assessment
· Uses direct observation or role-play to assess an individual's thoughts, feelings, and behavior in specific situations or contexts
· Target behaviors are identified and observed with the goal of determining antecedents and consequences
· ABC's - Antecedent, Behavior, Consequence
o Antecedent: what event or action occurred immediately before the behavior
o Behavior: what did the person do (should be an observable action)
o Consequence: what action or response immediately followed the behavior
· Likely done in the patient's home/work/school environment (often outside of clinic) - can be done in one setting or multiple
neuropsychological testing
· Measure abilities in areas such as receptive and expressive language, attention and concentration, memory, motor skills, perceptual abilities, and learning and abstraction
· Allow the clinician to make inferences about brain functioning and organic damage
structural imaging methods
CAT/CT scans; sMRIs
computerized axial tomography (CAT) or CT scans
utilizes x-rays
structural magnetic resonance imaging (sMRI)
Utilizes strong magnetic fields
Better resolution than CT scan
functional imaging methods
PET and SPECT scans; fMRI
positron emission tomography (PET) and single photon emission computed tomography (SPECT) scans
involve injection of radioactive isotopes
functional MRI (fMRI)
uses blood-oxygen-level dependent (BOLD) signal to identify brain activity patterns
psychophysiological assessment
· Measure changes in indicators of nervous system functioning that reflect emotional or psychology events
o Electroencephalogram (EEG) measures electrical activity in the brain
o Heart rate, respiration, cortisol, skin conductance (i.e., sweat gland activity) controlled by the peripheral nervous system
classification/diagnosis
Degree of fit between symptoms and diagnostic criteria (currently outlined in DSM); must be reliable and valid
construct validity
criteria are consistently associated and distinct from those for other diagnostic categories
predictive validity
tells the clinician what is likely to happen with the prototypical patient
content validity
criteria reflect the way most experts in the field think about the disorders
3 critiques of DSM-5
comorbidity, dimensionality, heterogeneity
comorbidity
o When one individual has more than one diagnostic category at the same time
o Pretty common
o People tend to have greater impairment, treatments tend to be more complex, and outcomes tends to be worse
o Hard to make out individual causes of disorders
dimensionality
o Having cut offs for what meets the disorder and what doesn't, may not reflect how people really are
o Could lead to people not getting treatment that they need because they don't meet the requirements
heterogeneity
So many ways symptoms can manifest in individuals with disorders
alternate classification systems
HiTOP and RDoC
the hierarchal taxonomy of psychopathology (HiTOP)
o Looks empirically at the structure of psychopathology
o Combines individual signs and symptoms into homogenous components/traits and syndromes
research domain criteria (RDoC)
o Integrate many levels of information to explore the full range of human behavior
o Goal is to understand the nature of mental health and illness
o Not meant for diagnosis (yet) but rather to better inform research into the causes of mental disorders