Cartilage and Bone

LSU SVM

What are the components of cartilage?

chondroblasts/cytes + ECM

Does cartilage have any blood supply or innervations?

no

What is the function of chondroblasts?

to actively make the matrix of cartilage

Where do chondroblasts grow?

within cartilage

What are chondrocytes?

less active chondroblasts

Where do chondrocytes grow?

in lacunae within cartilage

What is perichondrium?

fibrous connective tissue of cartilage

What are the two layers of the perichondrium?

outer fibrous layer and inner cellular layer

What is the function of hyaline cartilage?

foundation for fetal skeletons and provide stiff but somewhat flexible support and reduces friction between bony surfaces

What type of collagen is hyaline cartilage made of?

very fined-sized type 2 collagen fibers

What is the most abundant cartilage? Identified by it’s semitranslucent matrix.

hyaline cartilage

Where can you find hyaline cartilage?

covering bone surfaces at synovial joints

What cartilage only has perichondrium on non-articular surfaces?

hyaline cartilage

Which cartilage has the most amount of matrix?

hyaline cartilage

What cartilage has a scant amount of matrix?

fibrocartilage

What cartilage always has perichondrium present?

elastic cartilage

What are the components of elastic cartilage?

type 2 collagen and elastic fibers interwoven in small amount of ground substance

What is the function of elastic cartilage?

provide support while being able to tolerate distortion without damage and return to original shape

What kind of cartilage is found where resilient and springiness are needed?

elastic cartilage

Which cartilage has no perichondrium cover at all?

fibrocartilage

What is the collagen component of fibrocartilage?

type 1 in annulus and type 2 in pulposus

Where is fibrocartilage located?

intervertebral disks

What is the function of fibrocartilage?

resist compression/deformation to prevent bone to bone contact

Which cartilage is capable of withstanding compression forces?

fibrocartilage

What is the only cartilage that does not undergo calcification?

elastic cartilage

Which cartilage grow via interstitial and appositional growth?

hyaline and elastic cartilage

Which cartilage grows only via interstitial growth?

fibrocartilage

Which cartilage is shown in the following image?

hyaline cartilage

Which cartilage is shown in the following image?

elastic cartilage

Which cartilage is shown in the following image?

fibrocartilage

Which cartilage is shown in the following image?

elastic cartilage

Which cartilage is shown in the following image?

hyaline cartilage

Which cartilage is shown in the following image?

fibrocartilage between two vertebra

What kind of bone is shown in the following image?

compact bone

What kind of bone is shown in the following image?

trabecular (spongy)

What is the function of osteoblasts?

actively make matrix

What is the function of osteocytes?

maintains matrix

What is the function of osteoclast?

resorbs and regulates matrix

What is the lifespan of an osteoblast?

couple of weeks

What is the lifespan of an osteocyte?

10-20 days

What is the lifespan of an osteoblast?

few days

What bone cells only have one nucleus?

osteoblast and osteocytes

What bone cell is multi-nucleated?

osteoclasts

If you remove the organic bone matrix, what occurs to the bone?

becomes brittle

If you remove the inorganic bone matrix, what occurs to the bone?

becomes soft, flexible, and pliable