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Intraperitoneal
Organ suspended in mesentery (stomach, spleen, transverse colon)
Primarily retroperitoneal
Organ develops behind the peritoneum and stays there throughout development (esophagus, last 2/3 of rectum, anal canal, kidneys)
Secondarily retroperitoneal
Organ develops within the mesentery (intraperitoneal) and is now posterior to the mesentery due to rotation and mesenteric fusing (duodenum parts 2-4, ascending and descending colon, pancreas)
Foregut
Esophagus through the first part of the duodenum; also includes pancreas, spleen, liver, and gallbladder; supplied by the celiac trunk; outpocketings include pharyngeal pouches, lower respiratory system, pancreas, liver, and gallbladder
Midgut
Duodenum through 2/3 of the transverse colon; supplied by the superior mesenteric artery
Hindgut
Last 1/3 of the transverse colon through the anus; supplied by the inferior mesenteric artery; outgrowths are urinary bladder and urethra
Celiac trunk
Supplies the foregut; branches are the left gastric, splenic, common hepatic
Left gastric artery
Branch of the celiac trunk that goes to the lesser curvature of the stomach; anastomoses with the right gastric artery
Splenic artery
Branch of the celiac trunk that passes behind the stomach and pancreas to serve the spleen; branches include dorsal and greater pancreatic, short gastric, and left gastro-omental
Pancreatic arteries
Branches of the splenic artery of the celiac trunk; dorsal branch supplies the body of the pancreas and the greater branch supplies the tail
Short gastric arteries
Branches of the splenic artery of the celiac trunk that supply the stomach closest to the spleen
Left gastro-omental artery
Branch of the splenic artery of the celiac trunk that supplies the left side of the greater curvature of the stomach
Common hepatic artery
Major branch of the celiac trunk that goes toward the right side (liver); branches include gastroduodenal, right gastric, and proper hepatic
Gastroduodenal artery
Branch of the common hepatic artery of the celiac trunk; gives rise to right gastro-omental, superior pancreaticoduodenal, and supraduodenal arteries
Right gastro-omental artery
Branch of the gastroduodenal artery of the common hepatic artery of the celiac trunk; goes to the right side of the greater curvature of the stomach
Superior pancreaticoduodenal artery
Branch of the gastroduodenal artery of the common hepatic artery of the celiac trunk; goes to the stomach, pancreas, and head of duodenum
Supraduodenal artery
Branch of the gastroduodenal artery of the common hepatic artery of the celiac trunk; goes to the superior duodenum; is sometimes absent
Right gastric artery
Branch of the common hepatic artery of the celiac trunk; goes to the right lesser curvature of the stomach; anastomoses with the left gastric artery
Proper hepatic artery
Branch of the common hepatic artery of the celiac trunk; branches include right hepatic and left hepatic arteries
Right hepatic artery
Branch of the proper hepatic artery of the common hepatic artery of the celiac trunk; goes to the liver; gives off the cystic artery to the gallbladder
Superior mesenteric artery
Supplies the midgut (and collaterally the pancreas); branches include inferior pancreaticoduodenal, intestinals, ileocolic, right colic, middle colic, and marginal arteries
Inferior pancreaticoduodenal artery
Branch of the superior mesenteric artery; goes to the head of the pancreas and the duodenum
Intestinal arteries
Branches of the superior mesenteric artery; go to the jejunum and ileum; branch off into arcades which loop in the mesentery and vasa rectae which come off the arcades
Ileocolic artery
Branch of the superior mesenteric artery that goes to the distal ileum and cecum
Right colic artery
Branch of the superior mesenteric artery that foes to the ascending colon
Middle colic artery
Branch of the superior mesenteric artery that goes to the transverse colon
Marginal artery
Anastomotic branch of the superior mesenteric artery that circles the colon; formed by branches of the ileocolic, right colic, middle colic, and left colic (IMA); gives rise to vasa rectae
Inferior mesenteric artery
Supplies the hindgut; branches include left colic, sigmoid, and superior rectal arteries
Left colic artery
Branch of the inferior mesenteric artery that goes to the descending colon; anastomoses with the ileocolic, right colic, and middle colic arteries to form the marginal artery
Sigmoid arteries
Branches of the inferior mesenteric artery that goes to the sigmoid colon
Superior rectal arteries
Branches of the inferior mesenteric artery that go to the proximal rectum
Important anastomoses
Right and left gastro-omentals, right and left gastrics, superior and inferior pancreaticoduodenals, inferior pancreaticoduodenal and jejunal arteries, ileocolic/right colic/middle colic/left colic, superior rectals with middle and inferior rectals
Portal system
Goes through two capillary beds before returning to the heart; deoxygenated blood from the abdomen passes through the hepatic system before returning to the heart via the inferior vena cava
Hepatic portal system
Major portal system in the human body; main branches include splenic vein from the foregut, superior mesenteric vein of the midgut, and inferior mesenteric vein of the hindgut; veins converge to form the hepatic portal vein which goes to the liver to get filtered; hepatic vein brings filtered blood back to the heart; has esophageal, rectal, umbilical, and colonic anastomoses
Liver enlargement
Can be caused by cirrhosis, valvular cardiac disease, hepatitis, hepatic tumors, and more; can cause portal hypertension
Portal hypertension
Blood pressure raises due to resistance of the diseased liver; blood finds alternate routes around the hepatic portal vein; can cause esophageal varices, external hemorrhoids, opening of umbilical vessels
Sympathetics of celiac plexus
Innervate the foregut; rise from T5-T9 spinal nerve levels; presynaptics pass through the sympathetic chain; pass through the greater splanchnic nerve; synapse in the celiac ganglia; postsynaptics follow branches of celiac trunk to target organs
Parasympathetics of celiac plexus
Innervate the foregut; arise from the brain and pass through vagus nerve; pre-synaptics pass through celiac plexus; follow branches of celiac trunk to targets; synapse in ganglia in the gut plexuses; postsynaptics reach targets via short postsynaptics fibers
Sympathetics of superior mesenteric plexus
Innervate the midgut; arise from T10-T12 spinal nerve levels; presynaptics pass through sympathetic trunk; pass through lesser or least splanchnic nerve; synapse in superior mesenteric ganglion; postsynaptics follow branches of superior mesenteric artery to target organs
Parasympathetics of superior mesenteric plexus
Innervate the midgut; arise from the brain and pass through vagus nerve; pass through superior mesenteric plexus without synapsing; follow branches of superior mesenteric artery to targets; synapse in ganglia in gut plexuses; postsynaptics reach targets via short postsynaptic fibers
Sympathetics of inferior mesenteric and hypogastric plexuses
Innervate hindgut; arise from L1-L2 spinal levels; presynaptics pass through sympathetic trunk; pass through lumbar splanchnic nerves; synapse in inferior mesenteric ganglion; postsynaptics follow branches of inferior mesenteric artery to target organs
Parasympathetics of inferior mesenteric and hypogastric plexuses
Innervate hindgut; arise from S2-S4 spinal levels; pass through sacral spinal nerves; pass through pelvic splanchnic nerve; branches to colon pass cranially through hypogastric plexus and inferior mesenteric plexus; follow branches of inferior mesenteric artery to targets; synapse in ganglia in gut plexuses; postsynaptics reach targets via short postsynaptic fibers
Referred pain in abdomen
Visceral afferents share rami communicans coming back from somatic nerves, so brain perceives signals as coming from somatics themselves
Cranial-caudal folding
Occurs 4 weeks into development; embryo forms a primitive endodermal gut tube connected to the yolk sac via the yolk stalk; provides nutrients for 2 weeks; functions as the primordial gut and its endoderm forms the gut tube and respiratory tract; these germ cells also give rise to gonads and blood develops here until liver is functional
Recanalization
During weeks 5-6 gut tube lumen becomes narrow due to epithelial cell development; vacuoles form and hollow out the gut tube; failure most commonly occurs at the duodenum
Ventral mesentery
Connected the ventral body wall to the gut tube; by birth, it is not connected to the body wall except for the falciform ligament; remnants can also be found in the lesser omentum
Dorsal mesentery
Connects the dorsal body wall to the gut tube; provides mesentery for most abdominal organs
Polyhydramnios
Too much amniotic fluid in the cavity; means the fetus is unable to drink fluid and indicates a blockage due to recanalization failure
Non-rotation
Intestines grow but do not rotate
Subhepatic cecum and appendix
Cecum and appendix do not descend and stay in the top right quadrant; may present as gallbladder issues
Stomach development
Dorsal border grows faster than ventral border, producing greater and lesser curvatures; rotates 90 degrees clockwise bringing the vagus nerves with it; lesser curvature moves to the right and greater curvature moves to the left
Foregut duodenum development
Ends just distal to the common bile duct; solid ventral outgrowths form ducts for the liver, pancreas, and gallbladder
Pancreatic development
Forms a ventral and dorsal bud; if two ventral buds form and go opposite directions, can wrap around duodenum and cause a blockage
Splenic development
Not an endodermal derivative; outpocketing of mesoderm in dorsal mesentery
Median umbilical fold
Remnant of urachus, which drained the fetal bladder, and paraumbilical veins, which can become enlarged and patent during portal hypertension
Medial umbilical folds
Bilateral remnants of umbilical arteries
Lateral umbilical folds
Bilateral ridges of parietal peritoneum covering the inferior epigastric vessels
Midgut development
Small and large intestines herniate out of the umbilicus, then rotate 90 degrees counter-clockwise; grows and forms a loop with the superior mesenteric artery as its axis; small intestine returns to gut cavity while large intestine rotates another 180 degrees counter-clockwise; cecum and appendix descend to lower right
Cloaca
Forms the caudal hindgut; common outlet for fetal waste; gets divided by urorectal septum into urogenital membrane and anal membrane
Urorectal septum
Divides allantois and yolk stalk, separating cloaca into urogenital membrane and anal membrane
Pectinate line
Line of the anus where endoderm and ectoderm meet
Non-perforate anus
Anal opening does not develop properly; thin layer of tissue usually separates the anus from the outside
Anoperineal fistula
Anal opening is misplaced in the perineum; no anal sphincter
Rectourethral fistula
Tunnel connecting urethra to rectum; anus is usually absent or vestigial; feces exits penis
Rectovaginal fistula
Tunnel connecting rectum to vagina; anus is usually absent or vestigial; feces exits vagina
Kidneys
Positioned on the posterior body wall between T12 and L3; remove excess water/salts/wastes of protein metabolism; return nutrients to blood; regulate blood pressure and production of red blood cells; have pararenal and perirenal fat; consist of cortex and medulla; pyramids drain into minor calices which drain into major calices which drain into the pelvis
Kidneys blood supply
Renal artery, segmental arteries, interlobar arteries, arcuate arteries, renal vein
Kidneys innervation
Sympathetic from T10-L1; probably no parasympathetic
Hilum
Area of the kidney where all contents enter and exit; contains renal arteries, veins, and renal pelvis which becomes the ureter
Suprarenal glands
Cortex produces corticosteroids and androgens; medulla produces norepinephrine and epinephrine; blood supply from superior suprarenal (from inferior phrenic), middle suprarenal (from aorta), and inferior suprarenal (from renal) arteries
Suprarenal glands innervation
Medulla has presynaptic sympathetics penetrating directly and synapsing on chromaffin cells (sympathetic ganglion cells); cortex has autonomic fibers associated with blood cells controlling vasodilation and vasoconstriction
Diaphragm
Major muscle of respiration; motor and sensory innervation from phrenic nerve; intercostal nerves provide sensory innervation to periphery; right crus muscle wraps around esophagus; superior surface is supplied by superior phrenic arteries and inferior surface is supplied by inferior phrenic arteries
Hiatal openings
Holes in diaphragm where other structures pass through; vena cava at T8, esophagus at T10, aorta at T12
Psoas major origins
Transverse processes of lumbar vertebrae, side of vertebral bodies T12-S1
Psoas major insertions
Lesser trochanter of femur
Psoas major innervation
Lumbar plexus via anterior branches of nerves L1-L3
Psoas major actions
Flexes thigh, flexes vertebral column laterally, flexes trunk
Psoas minor origins
Sides of vertebral bodies T12-L1
Psoas minor insertions
Pectineal line and iliopubic eminence
Psoas minor innervation
L1
Psoas minor actions
Weak trunk flexor
Iliacus origins
Superior 2/3 of iliac fossa, ala of sacrum, anterior sacro-iliac ligaments
Iliacus insertions
Lesser trochanter of femur and shaft inferior to it
Iliacus innervation
Femoral nerve (L2-L4)
Iliacus actions
Flexes thigh and stabilizes hip joint
Quadratus lumborum origins
Medial half of inferior border of rib 12, tips of lumbar transverse processes
Quadratus lumborum insertions
Iliolumbar ligament and internal lip of iliac crest
Quadratus lumborum innervation
Anterior branches of T12 and L1-L4 nerves
Quadratus lumborum actions
Extends and laterally flexes vertebral column; fixes 12th rib during inspiration
Subcostal nerves
From ventral rami of T12; innervate external obliques and skin of anterolateral abdominal wall
Lumbar plexus
Arises from L1-L4; gives rise to iliohypogastric, ilioinguinal, genitofemoral, lateral femoral cutaneous, femoral, obturator, and accessory obturator nerves
Lumbosacral trunk
L4-L5; joins sacral plexus to form sciatic nerve
Iliohypogastric nerve
L1 of lumbar plexus; motor innervation to abdominal muscles and sensory innervation to overlying skin
Ilioinguinal nerve
L1 of lumbar plexus; sensory innervation to skin of inguinal and pubic regions (scrotum, labia majora, skin of medial thigh)
Genitofemoral nerve
L1-L2 of lumbar plexus; sensory innervation to skin below inguinal ligament; motor innervation to cremaster muscle
Lateral femoral cutaneous nerve
L2-L3 of lumbar plexus; sensory innervation to anterolateral skin of thigh
Femoral nerve
L2-L4 of lumbar plexus; motor innervation to iliacus, hip flexors, quadriceps; sensory innervation to skin of anterior leg
Obturator nerve
L2-L4 of lumbar plexus; sensory innervation to skin of medial thigh; motor innervation to thigh adductors
Accessory obturator nerve
May not be present; L3-L4 of lumbar plexus; motor innervation to pectineus muscle and hip joint
Subcostal arteries
Bring blood from the abdominal aorta to the posterior body wall inferior to the 12th rib