ID - Graft vs Host/Immunizations

How to DX GVH Dz

BX the rash

Xenograft

a graft from another species

Allograft

a graft between 2 members of the same species

Isograft

transplant between identical twins

MCC of death in GVH dz

Sepsis

Triad of GVH dz

Dermatitis, enteritis, hepatitis

Best treatment of GVH

Prevention

Prophylaxis with methotrexate +/- prednisone

Once GVHD is dx treat with

immunosuppressive agents and prednsione

Immunologically privledged tissues

Corneal graft

What vax is given to ALL patients over 6 mo unless CI

Influenza vax

Influenza vax - children ____ need 2 DOSES during their first season of vacciantion

6mo - age 8

All adults over 65 are now recommenede what for pneumococcal dz

Prevnar 20

When to consider seperating MMR and varicella vaccines

12-47 months due to increase risk of febrile seizures

Vaccination with live viruses may interfere with PPD reactions - what can u do

Give PPD on same day live-virus vax

or

4-6 wks after the live virus vax

Cancer preventing vaccines

HPV

HepB

Dosing HPV vaccine

9-14 = 2 dose series --> 0 and 6-12 mo

15 + = 3 dose series --> 0, 1-2 mo, 6 mo

Who needs Tdap

anyone taking care of an infant < 12 mo

Latest recommendation for Tdap

7yo and above with no age limit

Tdap and pregnancy?

Need booster with EACH PREGNANNCY**

Shingles vaccine

Shingrix

Needed to enter grade 7 or attende grades 7-12

Menigitis vax

Menigitis vax (mencentra) .. why give in HS

Peak at 16 yo

who is a candidate for group B strep vax

IC

Asplenic vaccinated agianst

Encapsulated

Neisseria

Strep pneumo

H.flu

____ for adults 75+ or adults 50-74 at increased risk

RSV vaccine

Most important thing with vaccines

check CDC for updates!