Immuno pathogens

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13 Terms

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Measles

Spreads through respiratory droplets; can wipe out 11-75% of antibodies

Symptoms: fever, cough, runny nose, red eyes, RED RASH

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Influenza

A contagious respiratory illness caused a virus; can cause mild to severe illness and can lead to hospitalization and death.

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Bare Lymphocyte Syndrome

B + T cells present but dont work well; inability to produce MHCII + MHCII for cell presentation

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Wiskott-Aldrich Syndrome

Low IgM production with excessive bleeding due to platelet dysfunction and increased susceptibility to infections.

This X-linked condition affects primarily males and is characterized by eczema, recurrent infections, and thrombocytopenia.

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DiGeorge Syndrome

Thymic aplasia/hypoplasia (Low parathyroid function) leading to decreased T cell and calcium production

Caused by chromosome 22 deletion, leading to developmental defects and immune deficiency.

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Hypersensitivity Type 1

IgG binds to receptors on mast cells that trigger histamine release from degranulation

Symptoms include allergic reactions such as hives, asthma, and anaphylaxis.

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Hypersensitivity Type 2

IgG binds to surface antigens on cells, leading to cell destruction through phagocytosis.

Soluble antigens enter circulation and damage tissues through complement system → antibodies mark on cells to destroy them where antibodies dont kill them but cause malfunction

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Hypersensitivity Type 3

IgG and IgM antibodies form immune complexes with soluble antigens through compliment activation → leading to inflammation and tissue damage

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Systemic Lupus Erythematosus

chronic autoimmune condition where antibodies attack the body. It can affect multiple organ systems and is characterized by periods of flares and remission.

Symptoms: mouth ulcers, pleauritis, pnemonitis, pulmonary emboli, blood in urine (hematuria) BUTTERFLY RASH ON CHEEKS, abdominal pain, endocarditis, artherosclerosis, anemia, hypertension, swollen joints, arthritis, pain in joints and fatigue.

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Bacteremia

presence of bacteria in blood

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Septicemia

growth of bacteria in blood

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Dermatophytes

fungi infecting hair, skin or nails

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Protozoa

infections from parasites that can cause diseases in humans and animals, often transmitted through contaminated water or food.