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Functions of the liver
Detoxification, manufacture of bile, storage of glycogen, phagocytosis, and tissue regeneration.
Detoxification (liver)
Removes toxins from the blood.
Manufacture of bile
Produces bile to aid fat digestion.
Storage of glycogen
The liver stores glucose in the form of glycogen.
Phagocytosis
Ingestion and elimination of particles by Kupffer cells.
Macroscopic relationship of the liver
Duodenum, right kidney, gallbladder, transverse colon, pancreas.
Location of the liver
Right upper quadrant (RUQ).
What lies inferior to the diaphragm?
Peritoneal cavity.
Fluid inferior to the diaphragm is called
Ascites.
Fluid superior to the diaphragm is called
Pleural effusion.
Pleural effusion
Fluid within the pleural space surrounding the lungs.
Ascites
Fluid within the peritoneal cavity.
Hepatomegaly definition
Cranial-caudal liver measurement greater than 13–15 cm (130–150 mm).
13 cm in mm
130 mm.
15 cm in mm
150 mm.
Patient maneuver to move bowel gas
Deep inspiration and hold breath.
Morrison's pouch
Space between the liver and right kidney.
Another name for Morrison's pouch
Hepatorenal recess.
Portal triad
Common bile duct, hepatic artery, main portal vein.
Components of the portal triad
Common bile duct, hepatic artery, main portal vein.
Portal veins on ultrasound
Have echogenic walls.
Why are portal vein walls echogenic?
They are surrounded by fibrous tissue.
Riedel's lobe
Normal tongue-like extension of the right lobe.
Riedel's lobe is most common in
Females.
Riedel's lobe is a
Normal anatomic variant.
Caudate lobe location
Posterosuperior surface of the liver.
Caudate lobe relationship to IVC
Anterior to the IVC.
Structure anterior to the caudate lobe
Ligamentum venosum.
Main lobar fissure
Echogenic line between the gallbladder neck and right portal vein.
Main lobar fissure divides
Right and left lobes.
Middle hepatic vein divides
Right and left lobes.
Left hepatic vein divides
Medial and lateral segments.
Right hepatic vein divides
Anterior and posterior segments of the right lobe.
Ligamentum teres
Remnant of fetal umbilical vein.
Another name for ligamentum teres
Round ligament.
Ligamentum teres ultrasound appearance
Circular echogenic dot at the porta hepatis.
Ligamentum teres artifact
Strong attenuator causing posterior shadowing.
Normal liver echogenicity
Slightly hyperechoic to the renal cortex.
Portal veins are largest at the
Porta hepatis.
Portal veins course
Horizontally.
Portal veins run
Intrasegmentally.
Right portal vein branches
Anterior and posterior branches.
Main liver function tests
ALT and AST.
ALT
Alanine aminotransferase.
AST
Aspartate aminotransferase.
Increased AST indicates
Liver cell necrosis.
Increased ALT indicates
Liver cell necrosis.
Probe position for sagittal left lobe
Epigastric region.
Fibrous capsule of the liver
Glisson's capsule.
Normal liver capsule
Glisson's capsule.
Portal vein formation
Union of the splenic vein and superior mesenteric vein.
Portal vein enters liver at
Porta hepatis.
Portal vein oxygen supply
Provides approximately 50–60% of the liver's oxygen requirement.
Portal vein walls
Thick and echogenic.
Normal liver appearance
Homogeneous and slightly brighter than the kidney.
Acute hepatitis ultrasound
May appear normal.
Acute hepatitis echogenicity
May be decreased.
Acute hepatitis findings
Enlarged liver, accentuated portal vein walls, thickened gallbladder wall.
Chronic hepatitis ultrasound
Coarse echotexture with increased echogenicity.
Cause of hepatitis
Hepatitis viruses.
Types of hepatitis
A, B, C, D, E, F (rare).
Most serious hepatitis types
B and C.
Complications of hepatitis
Cirrhosis, liver failure, hepatocellular carcinoma.
Fatty infiltration definition
Accumulation of lipids within liver cells.
Fatty infiltration is
Acquired and reversible.
Diffuse fatty infiltration
Entire liver is hyperechoic and enlarged.
Diffuse fatty liver findings
Hyperechoic liver, paucity of vessels, hepatomegaly.
Focal fatty infiltration
Localized areas of increased echogenicity.
Focal fatty infiltration can mimic
A liver mass.
Early cirrhosis findings
Hepatomegaly and fatty infiltration.
Cirrhosis definition
Progressive irreversible replacement of liver tissue by fibrosis and nodules.
Cirrhosis complications
Portal hypertension, ascites, splenomegaly, hepatocellular carcinoma.
Portal hypertension definition
Increased portal venous pressure due to impaired liver flow.
Portal hypertension ultrasound findings
Dilated portal vein, splenomegaly, hepatofugal flow, recanalized umbilical vein, ascites.
Portal vein diameter in portal hypertension
Greater than 13 mm.
Splenic vein diameter in portal hypertension
Greater than 10 mm.
SMV diameter in portal hypertension
Greater than 10 mm.
Normal portal flow
Hepatopetal.
Flow away from liver
Hepatofugal.
Portal hypertension collateral veins
Epigastric collateral veins may develop.
Recanalized ligamentum teres
Seen with portal hypertension.
Caput medusae
Collateral abdominal veins caused by portal hypertension.
Most common malignant liver tumor
Metastases.
Bull's-eye sign is associated with
Liver metastases.
Target sign is another name for
Bull's-eye sign.
Metastatic liver lesions may appear
Hypoechoic, hyperechoic, complex, cystic, calcified, patchy, or moth-eaten.
Condition with highest risk of HCC
Cirrhosis.
Hepatocellular carcinoma risk factor
Cirrhosis.
Focal nodular hyperplasia
Benign liver tumor.
Patients at risk for FNH
Females under 40 using oral contraceptives.
FNH ultrasound appearance
Variable; hypoechoic, hyperechoic, or isoechoic.
Oral contraceptives are associated with
Focal nodular hyperplasia.
Liver abscess types
Pyogenic and amoebic.
Pyogenic abscess cause
Bacterial infection.
Amoebic abscess cause
Amebas entering through the portal vein.
Pyogenic abscess symptoms
Fever, pain, nausea, vomiting, diarrhea.
Pyogenic abscess ultrasound
Irregular walls, variable echogenicity, posterior enhancement possible.
Amoebic abscess ultrasound
Subcapsular, irregular walls, good through transmission.
Country travel risk for
Amoebic liver abscess.
Echinococcal cyst
Cystic liver lesion caused by hydatid disease.