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Pathophysiology Exam 3
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What are the key factors that maintain healthy bones?
Adequate calcium intake
Adequate vitamin D
Regular weight-bearing exercise
Balanced nutrition
Normal hormone levels
Avoiding smoking and excessive alcohol
Why is calcium important?
Calcium is the primary mineral that provides bone strength and hardness
Why is vitamin D essential?
It helps the intestines absorb calcium and phosphorus, which are necessary for bone mineralization
What type fof exercise best promotes bone health?
Weight-bearing exercises, such Asas walking, jogging, dancing, and strength training
Why does weight-bearing exercise strengthen bones?
Mechanical stress stimulates osteoblasts to build new bone
Which lifestyle habits increase the risk of weak bones?
Smoking
Excessive alcohol intake
Physical inactivity
Poor nutrition
What structures help keep joints healthy?
Healthy cartilage
Synovial fluid
Strong muscles
Ligaments
Tendons
What is the function of cartilage?
It cushions the ends of bones and reduces friction during movement
What is the function of synovial fluid?
It lubricates joints and nourishes articular cartilage
Why are strong muscles important for joint health?
They stabilize joints and reduce stress on bones and ligaments
How does obesity affect joints?
It increases stress on weight-bearing joints, especially the knees and hips
Which jointa are most commonly affected by wear and tear?
Knees
Hips
Spine
How can osteoporosis be prevented?
Adequate calcium
Vitamin D
Weight-bearing exercise
Smoking cessation
Limiting alcohol
Fall prevention
Why is fall prevention especially important in older adults?
Falls are a leading cause of fractures, especially in people with osteoporosis
Name three fall-prevention strategies?
Remove loose rugs and tripping hazards
Ensure adequate lighting
Use assistive devices if needed
What is osteoporosis?
A disease characterized by decreased bone density and deterioration of bone structure, making bones fragile and more likely to fracture
Why do bones fracture more easily in osteoporosis?
Bone resorption exceeds bone formation, weakening the skeleton
Which cells are overactive in osteoporosis?
Osteoclasts (bone-resorbing cells)
Which bones are most commonly fractured in osteoporosis?
Hip
Vertebrae
Wrist
Who is at greatest risk for osteoporosis?
Older adults
Postmenopausal women
People with low body weight
Smokers
Long-term corticosteroid users
Individuals with family history
Why are postmenopausal women at increased risk?
Estrogen levels decrease, leading to increased bone resorption
How do corticosteroids contribute to osteoporosis?
They decrease bone formation and increase bone breakdown over time
Why is osteoporosis called the “silent disease”?
It often causes no symptoms until a fracture occurs
What symptoms may appear as osteoporosis progresses?
Loss of height
Kyphosis (stooped posture)
Back pain
Fragility fractures
What is a fragility fracture?
A fracture caused by minimal trauma, such as fall from standing height
Why do vertebral fractures cause off of height?
The weakened vertebrae compress and collapse
What is the gold standard test for diagnosing osteoporosis?
A DEXA (dual-energy X-ray absorptiometry) scan
What does a DEXA scan measure?
Bone mineral density (BMD)
Why are X-rays not the best screening test for osteoporosis?
Bone loss must be significant before it is visible on a standard X-ray
What lifestyle changes help treat osteoporosis?
Weight-bearing exercise
Adequate calcium
Vitamin D
Smoking cessation
Limiting alcohol
Fall prevention
Which medications are commonly prescribed for osteoporosis?
Bisphosphonates (first-line in many patients)
Other medications may be used based on individual risk and provider recommendations
How do bisphosphonates work?
They inhibit osteoclasts, slowing bone resorption and helping preserve bone density
What patient teaching is important when taking oral bisphosphonates?
Take with a full glass of water
Take on an empty stomach
Remain upright for at least 30 minutes after taking the medication
Follow the specific instructions for the prescribed medication
Why should patients remain upright after taking oral bisphosphonates?
To reduce the risk of esophageal irritation
What is the nurse’s primary goal in caring for a patient with osteoporosis?
Prevent fractures
What teaching should the nurse provide regarding home safety?
Remove tripping hazards
Install grab bars if needed
Wear supportive footwear
Improve lighting
Use assistive devices when appropriate
What is the most common complication of osteoporosis?
Fractures
What diagnostic test is most likely to appear on an exam question about osteoporosis?
DEXA scan
What medication class is most commonly associated with osteoporosis treatment?
Bisphosphonates
What is the single most important nursing goal for osteoporosis?
Prevent falls and fractures
What is degenerative disc disease (DDD)?
A condition in which the intervertebral discs gradually lose water, elasticity, and height, leading to pain and decreased spinal function
What are intervertebral discs?
Fibrocartilaginous cushions located between the vertebrae that act as shock absorbers and allow flexibility of the spine
Which parts of the spine are most commonly affected by DDD?
Servical spine (neck)
Lumbar spine (lower back)
Why does degenerative disc disease develop?
Aging and repeated stress cause discs to lose water content, making them thinner and less able t absorb shock
What are common risk factors for degenerative disc disease?
Aging
Repetitive lifting
Obesity
Smoking
Previous spinal injury
Genetics
Why does smoking increase the risk of DDD?
Smoking reduces blood flow and nutrient delivery to spinal discs, accelerating degeneration
What happens to spinal discs in DDD?
Lose water content
Become thinner
Lose elasticity
Provide less cushioning between vertebrae
How can DDD lead to nerve compression?
Disc degeneration and loss of height can contribute to disc bulging to narrowing of spaces where spinal nerves travel, leading to nerve irritation or compression
Why does DDD cause pain?
Degenerated discs provide less cushioning, increasing stress on the vertebrae and surrounding joints, ligaments, and nerves
What are the most common symptoms of DDD?
Chronic neck or low back pain
Stiffness
Pain that worsens with sitting, bending, or lifting
Pain that improves with changing positions or gentle movement in some people
When does DDD pain often worsen?
Prolonged sitting
Bending
Twisting
Lifting heavy objects
What symptoms may occur if spinal nerves are compressed?
Numbness
Tingling
Weakness
Pain radiating into the arms or legs (radicular pain)
What is sciatica?
Pain that radiates down the leg due to irritation or compression of the sciatic nerve or its nerve roots, often associated with lumbar spine disordersH
ow is degenerative disc disease diagnosed?
Medical history
Physical examination
Imaging studies
Which imaging study best evaluates intervertebral discs?
MRI
Why might X-rays still be ordered?
They can show disc space narrowing, spinal alignment, and bony changes, but they no not visualize discs as well as MRI
What is the initial treatment for most patients with DDD?
Activity modification
Physical therapy
Regular exercise as tolerated
Pain management
Which medications may be used for symptom relief?
NSAIDs (if appropriate)
Acetaminophen
Other medications may be prescribed depending on symptoms and patient factors
Why Is physical therapy important?
It strengthens the core and back muscles, improves flexibility, and supports the spine
When might surgery be considered?
If conservative treatment fails or there is significant nerve compression, progressive neurological deficits, or severe functional impairment
What lifestyle changes help manage DDD?
Maintain a healthy weight
Exercise properly
Use proper body mechanics
Avoid smoking
Stay physically active within recommended limits
Why is maintaining a healthy weight important?
It reduces stress on the spine and may help decrease symptoms
What body mechanics should patients use?
Bend at the knees and hips, not the waist
Keep objects close to the body when lifting
Avoid twisting while lifting
What is the hallmark of degenerative disc disease?
Progressive degeneration of the intervertebral discs leading to chronic neck or back pain
Which imaging test is most useful for evaluating DDD?
MRI
What is the first-line treatment for most patients with DDD?
Conservative management, including physical therapy, exercise, activity modification, and pain control
What symptom suggests nerve involvement in DDD?
Pain, numbness, tingling, or weakness radiating into an arm or leg