Intracellular Trafficking

Flashcards for key vocabulary related to intracellular trafficking and cellular organization.

Intracellular Trafficking

The process by which proteins are targeted, transported, and secreted within a cell.

Compartmentalization

The division of a cell into distinct regions or compartments, allowing for specialized functions.

Vesicle Trafficking

The movement of vesicles containing proteins or other molecules within the cell.

Endoplasmic Reticulum

An organelle that plays a key role in the synthesis and transport of proteins and lipids.

Golgi Apparatus

The cell organelle involved in modifying, sorting, and packaging proteins for secretion.

Lysosome

An organelle that contains digestive enzymes to break down waste materials and cellular debris.

Secretory Pathway

The series of steps that proteins undergo to be secreted from the cell.

SNARE Proteins

A family of proteins that mediate the fusion of vesicles with their target membranes.

Rab Proteins

A family of small GTPases involved in regulating vesicle trafficking and transport.

Clathrin

A protein that coats vesicles in the endocytic pathway, aiding in their formation and transport.

Brefeldin A

A fungal metabolite that disrupts protein transport from the endoplasmic reticulum to the Golgi apparatus.

Temperature-sensitive Mutants

Mutated yeast cells that exhibit defects in vesicle transport at non-permissive temperatures.