DNA Replication

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Where are nucleotides added to on the new strand

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24 Terms

1

Where are nucleotides added to on the new strand

3’ end

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2

Where does replication begin

Origin of replication (dumbass)

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3

What is a replication forks

the points where a DNA molecule is replicating

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4

What unwinds the DNA strands

DNA helicase

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5

What is synthesized by primase?

Primer (obviously)

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6

What is DNA polymerase

enzyme ha catalyzes the polymerization of nucleotides

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7

What does the leading strand do

grow quickly at the 3’ end

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8

What does the lagging strand do

grows slowly and in pieces because it’s backwards

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9

What are okazaki fragments

small discontinuous stretches of DNA

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10

How is DNA synthesized

From 5’ to 3’

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11

How are okazaki fragments joined together

DNA ligase

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12

What is the replication complex

replication enzymes working together

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13

True or false: Replication complex does move along DNA strand

False

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14

Where are replication complexes in eukaryotic cells

anchored to the nuclear matrix

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15

What are telomeres?

DNA sequence at the end of chromosomes

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16

True or false: telomeres do not contain genes

true

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17

What is the purpose of telomeres

cockblocks different chromosomes

prevents incorrect signaling

delays gene shortening

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18

What can replace lost telomere sequences

telomerase, stem/germ cells/most cancer cells

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19

What is telomerase

enzyme that replaces telomeres

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20

What are the 3 DNA repair mechanisms

proofreading, mismatch repair, excision repair

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21

What is proofreading

corrects errors during DNA replication

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22

What is a mismatch repair

several proteins look for mismatched base pairs

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23

When does mismatch repair occur

after replication

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24

What is excision repair

damaged nucleotides are removed

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