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Deoxyribonucleic acid (DNA)
The material in cells that stores genetic information as a sequence of nucleotide base pairs.
Double helix
The "twisted ladder" conformation of DNA.
Enhancer
In eukaryotes, a regulatory DNA sequence that can increase transcription from a promoter by binding to an activator protein.
Exon
A portion of the transcribed region of a eukaryotic gene that is represented in a mature messenger RNA molecule.
Functional RNA
An RNA molecule that carries out a function other than encoding a polypeptide.
Genetic code
The set of rules by which the nucleotide sequence in an mRNA is translated into an amino acid sequence in a polypeptide.
Genotype
The underlying genetic constitution of an organism.
Informational RNA
An RNA molecule that carries sequences that encode a polypeptide.
Intron
A portion of the transcribed region of a eukaryotic gene that is removed from the primary transcript before it exits the nucleus.
Mutation
A stably inherited change in the nucleotide sequence of DNA.
Phenotype
The observable (physical, behavioral) properties of an organism.
Polypeptide
A chain of amino acids.
Promoter
DNA sequence in the 5' upstream region of a gene to which RNA polymerase binds during transcription initiation.
Replication
Process by which DNA is duplicated, allowing for inheritance of genetic information.
RNA polymerase
The enzyme responsible for RNA synthesis.
Silencer
A DNA sequence regulatory element that can decrease transcription from a promoter by binding to a repressor.
Transcription
Process by which an RNA molecule is made from a DNA template during gene expression.
Translation
Process by which information in an mRNA molecule is used to direct the synthesis of a polypeptide.