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Virology
The study of viruses and viral diseases.
SEQ Evolution by Natural Selection
A process involving heritable variation in traits, environmental pressure, differential survival and reproduction, and changes in allele frequency over generations.
Heritable Variation in Traits
Genetic variation that must be present for evolution to occur.
Environmental Pressure
Factors such as limited resources and predators that affect survival and reproduction.
Differential Survival & Reproduction
The concept that individuals with beneficial traits survive and reproduce more effectively.
Frequency of Beneficial Traits
The increase in the prevalence of advantageous traits in a population over time.
Evolution
The change in allele frequencies in a population over generations.
Parts of a Phylogenetic Tree
Components such as root, nodes, basal taxon, and sister taxa that illustrate evolutionary relationships.
Root
The base of a phylogenetic tree representing the common ancestor of all taxa in the tree.
Node
A point in a phylogenetic tree where a lineage diverges from a common ancestor.
Basal Taxon
A lineage that diverges early in the evolutionary history of a group.
Sister Taxa
Two taxa that share an immediate common ancestor.
Polytomy
A branch point in a phylogenetic tree where more than two groups emerge, indicating uncertainty.
Monophyletic Group
A group consisting of a common ancestor and all its descendants.
Paraphyletic Group
A group that includes a common ancestor and some, but not all, of its descendants.
Polyphyletic Group
A group that does not include the most recent common ancestor of its members.
PSC (Phylogenetic Species Concept)
The smallest group of organisms that share an evolutionary history.
Dichotomies
Two-way branch points in a phylogenetic tree.
Branch Points / Nodes
Points that represent divergence from a common ancestor.
SEQ General Viral Replication Cycle (Lytic)
The process by which a virus replicates and assembles new viruses, leading to the destruction of the host cell.
Lytic Cycle
A viral replication cycle where the host cell is destroyed.
Lysogenic Cycle
A viral replication cycle where the virus integrates into the host genome and replicates with the host.
Host Cell Fate in Lytic Cycle
The host cell is destroyed (lysed).
Host Cell Fate in Lysogenic Cycle
The host cell survives while the virus integrates into the host bacterial chromosome.
Transmission in Lytic Cycle
Horizontal transmission from host to host.
Transmission in Lysogenic Cycle
Vertical transmission passed to daughter cells or host offspring.
Viral DNA Status in Lytic Cycle
Active replication occurs immediately after entry.
Viral DNA Status in Lysogenic Cycle
Viral DNA integrates into the host genome and becomes a prophage.
Virus Type in Lytic Cycle
Virulent phages that are only capable of the lytic cycle.
Virus Type in Lysogenic Cycle
Temperate phages that can perform both lytic and lysogenic cycles.
Conditions for Lytic Cycle
Triggered by stress or poor host conditions.
T4 bacteriophage
Lambda phage (λ)
Prokaryotes
Cells that lack a nucleus and membrane-bound organelles.
Eukaryotes
Cells that have a nucleus and membrane-bound organelles.
Nucleus
A membrane-bound structure that contains the cell's genetic material.
Cell Size
Prokaryotes are smaller (~1-10 micrometers) while Eukaryotes are larger (~10-100 micrometers).
Cell Wall
Prokaryotes often have a cell wall with peptidoglycan; Eukaryotes have cell walls made of cellulose or chitin.
Gram +
Bacteria with a thick peptidoglycan wall that stains purple in gram stain and are less likely to cause serious disease.
Gram -
Bacteria with a thin peptidoglycan wall that stains pink in gram stain and are more likely to cause serious disease.
Cell Type
Prokaryotes are unicellular ONLY; Eukaryotes can be unicellular or multicellular.
Ribosomes
Prokaryotes have smaller ribosomes; Eukaryotes have larger ribosomes.
Flagellum
A structure used by prokaryotes for locomotion, powered by a proton gradient.
DNA Structure
Prokaryotes have circular DNA; Eukaryotes have linear chromosomes.
Modes of Reproduction
Prokaryotes reproduce asexually via binary fission; Eukaryotes can reproduce sexually or asexually.
Domains
Prokaryotes are classified into Bacteria and Archaea; Eukaryotes are classified into Eukarya.
Binary fission
A rapid (under optimal conditions), asexual reproduction method in prokaryotes resulting in identical offspring.
Mutation
Spontaneous changes in DNA during replication that occur in both prokaryotes and eukaryotes.
Genetic Recombination
The exchange of genetic material from different sources, occurring in both prokaryotes and eukaryotes.
Transformation
The uptake of foreign DNA from the environment by a cell.
Transduction
A process where a virus accidentally grabs bacterial DNA and transfers it to a new bacterium.
Conjugation
Direct DNA transfer via pilus from F- to F+ bacteria.
Energy Source / Carbon Source
Prokaryotes can be autotrophs (inorganic) or heterotrophs (organic).
Obligate aerobes
Organisms that require oxygen for survival.
Obligate anaerobes
Organisms that are poisoned by oxygen and use fermentation or anaerobic respiration.
Facultative anaerobes
Organisms that use oxygen when available but can switch to anaerobic methods when it is not.
Bacteria
Prokaryotic organisms that have peptidoglycan in their cell walls.
Archaea
Prokaryotic organisms that do not have peptidoglycan in their cell walls.
Eukaryotic Cells
Cells characterized by the presence of a nucleus and membrane-bound organelles.
Size of Eukaryotic Cells
Eukaryotic cells range from 10-100 micrometers.
Cytoskeleton
Well-developed (helps w/ structure + enables shape & asymmetry)
Cell Type
Unicellular or multicellular
Reproduction
Mitosis or Meiosis
DNA Structure
Linear chromosomes in nucleus
Ancestral Archaean
Anaerobic organism that engulfs aerobic alpha-proteobacterium
Eukaryote with mitochondria
Result of Primary Endosymbiosis - phagocytosis of bacterium by larger cell
Photosynthetic Eukaryote
E.g., Green Alga; formed from engulfing cyanobacterium
Eukaryote with Secondary Plastid
Result of Secondary Endosymbiosis - bigger heterotrophic eukaryote engulfs smaller autotrophic eukaryotic
Cellularity
Mostly unicellular; some colonial or multicellular
Nutrition Types
Heterotrophs, photoautotrophs, mixotrophs (does photosynthesis + consumes other organisms)
Relevance
First eukaryotic cells (~1.8 BYA); evolved ~1 billion years before plants, fungi, animals
Organization
Complex internal structures despite often being unicellular.
Morphology
Highly diverse (amoebas, algae, etc.)
Evolutionary Term
"Protist" = outdated and paraphyletic, but still commonly used.
Archaeplastida
Primary plastids (from cyanobacteria); includes red algae, green algae, land plants
SAR
Secondary plastids from red algae (via secondary endosymbiosis)
Stramenopiles
Hairy + smooth flagella; includes diatoms, golden algae, brown algae
Alveolates
Alveoli (flattened vesicles just inside the plasma membrane that support the membrane); includes dinoflagellates, apicomplexians, ciliates
Rhizarians
Genetic traits, shells made of calcium/silica
Amoebozoa
Love/tube-shaped pseudopodia; includes slime molds, entamoebas
Opisthokonta
Posterior flagellum, diverse group, related to fungi/animals; includes animals, fungi, choanoflagellates, nucleariids
Euglenids
A type of protist
Trypanosomes
A type of protist
Discoba
Crystalline rod in flagella, some have 2º plastids from green algae → mixotrophic
Eukaryotes
Organisms with complex cells that have a nucleus.
SAR Supergroup
Includes groups with secondary plastids from red algae via secondary endosymbiosis.
Stramenopiles
Includes Diatoms, Golden Algae, Brown Algae (hairy + smooth flagella).
Alveolates
Includes Dinoflagellates, Apicomplexans, Ciliates (membrane-bound sacs).
Rhizarians
Includes Radiolarians, Foraminiferans, Cercozoans (calcium-based shells).
Archaeplastida
Includes groups with primary plastids from cyanobacteria.
Red Algae
Multicellular, red pigment, found in deep water.
Green Algae
Includes Chlorophytes (mostly freshwater, unicellular or colonial) and Charophytes (sister group to land plants).
Land Plants
Not algae; evolved later from Charophytes.
Unikonta
Includes Amoebozoans and Opisthokonta.
Amoebozoans
Characterized by lobe-shaped pseudopodia.
Opisthokonta
Includes Nucleariids (sister group to fungi), Fungi, Choanoflagellates (sister group to animals), and Animals.
Fungi
Ancient lineage; absorptive heterotrophs.
Nucleariids
Amoeba-like; filose pseudopodia.
Chytrids
Primitive fungi; flagellated spores.
Hyphae
Long threadlike structures that make up the main body of fungus; filamentous.
Aerial hyphae
Special structures that reach up & release spores into the air.