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exocrine glands
secrete products into duct
endocrine glands
secretes products into bloodstream
heterocrine glands
both endocrine and exocrine functions
target cells
cells that have specific receptors for a hormone and respond to that hormone’s signal
difference between positive and negative feedback
negative feedback reduces/shuts off original stimulus (insulin regulation) (maintains homeostasis); positive feedback amplifies original stimulus (childbirth)
describe the two lobes of the pituitary gland
anterior lobe (adenohypophysis) and posterior lobe (neurohypophysis)
adenohypophysis
makes and releases hormones like hGH, ACTH, TSH
neurohypophysis
stores and releases hormones made by the hypothalamus (oxytocin and ADH)
number of hormones released by hypothalamus
9 (7 for adeno and 2 for neuro)
hormones released by anterior pituitary (adenohypophysis)
GH (growth hormone), ACTH, TSH, FSH, LH, PRL (prolactin), MSH
growth hormone function
stimulates growth and cell reproduction
ACTH function
stimulates adrenal cortex to release cortisol
TSH
releases thyroid hormone
FSH
stimulates egg/sperm production
LH
triggers ovulation/testosterone production
prolactin
stimulates milk production
MSH
affects skin pigmentation
hormones released by posterior pituitary (neurohypophysis)
oxytocin, ADH
oxytocin
stimulates uterine contraction and milk ejection
ADH (antidiuretic hormone)
reduces water loss by increasing water reabsorption in kidneys
hormones released by thyroid
T3, T4, calcitonin
T3 and T4
regulate metabolism, heartrate, and temp
calcitonin
lowers blood calcium levels by promoting calcium storage in bones
hormone released by parathyroid
PTH
parathyroid hormone (PTH)
raises blood calcium levels by stimulating bone breakdown and increasing calcium absorption in kidneys and intestines
hormones released by adrenal cortex
aldosterone, cortisol, androgens
aldosterone
regulates sodium and potassium levels
cortisol
helps control metabolism and stress response
androgens
supports development of sex characteristics
hormones released by adrenal medulla
epinephrine and norepinephrine
epinephrine/norepinephrine
triggers fight or flight response; increase heart rate, BP, and energy availability
where are endocrine cells found in the pancreas
islets of langerhans
alpha cells
release glucagon; raises blood sugar
beta cells
release insulin; lowers blood sugar
sex hormones
estrogen, progesterone, testosterone
hormones produced by ovaries
estrogen and progesterone
hormone produced by testes
testosterone
secondary sex characteristics
physical traits that appear during puberty that distinguish males from females
hormone released by pineal gland
melatonin
melatonin
regulates sleep-wale cycles
(circadian rhythms)
where is the thymus located
in the upper chest behind the sternum
how does the thymus shrink as we age
it shrinks and becomes mostly fatty tissue after puberty
what do thymic hormones do
help develop and mature T cells
hormones released by the kidneys
erythropoietin (EPO), renin, calcitriol
erythropoietin
stimulates RBC production
renin
regulates BP
calcitriol
active form of vitamin D; increase calcium absorption
hormone released by heart
atrial natriuretic peptide
atrial natriuretic peptide
(ANP)
lowers BP by causing kidneys to excrete sodium and water
grave’s disease
causes hyperthyroidism (leads to weight loss, fast heartbeat, bulging eyes)
disorders caused by irregular release of HGH
too much in kids (giantism), too much in adults (acromegaly), too little (dwarfism)