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Vitamin B 12
Also known as cyanocobalamin. Maturation factor
Folic acid
Co factor for DNA synthesis and methyl donor for VIT B 12
Iron
Interacts with tetracyclines and antacids
Epoietin
Erythropiesis stimulating agent that binds to commited progenitor cells
Filgrastim
Stimulates commited progenitors. Recombinant human GCSF
Lenograstim
Gcsf, not usually used in vet med
Serratia marcescens extract
Stimulates cytokine production but not commercially available
Heparin, clopidogrel bisulfate, EDTA, Coumarin derivatives, aspirin, acid citrate dextrose
Example of anticoagulants
Heparin
Prevents the conversion of prothrombin to thrombin. May treat DIC or laminitis in horses
Clopidogrel bisulfate
Inhibits platelet aggregation, prevents ADP binding, prevents thrombi formation in cats
EDTA
Chelates calcium, Tx of lead poisoning.
Coumarin derivatives
Blocks vit k conversion; for long term tx of thromboembolism
Warfarin
Ex. Of coumarin deriv
Aspirin
Inhibits COX 1. Prevents thromboembolism assoc. W/ CHW and cardiomyopathies. Side effects gi bleeding and vomiting
Acid citrate dextrose
Chelates calcium. Used in blood bags
Phytonadione, protamine sulfate, tranexamic acid, styptics
Hemostatics
Phytonadione
VIT K 1, Tx of rodenticide poisioning. Side effect: anaphylaxis
Protamine sulfate
Alkaline protein for heparic toxicity and brackden fern poisoning, se: hypotension, bradycardia
Tranexamic acid
Synthetic derivative of lysine. Binds to lysine binding site on plasminogen. Se: nausea
Styptics
Silver nitrate, hemostat powder, gelfoam/gelatin sponge, topical thrombin sol.
Opioids/benzodiazepine
Sedatives for dogs for blood transfusion
Ketamine/Diazepam
Sedatoves for cats for blood transfusion
G18-16
Needle used for blood collection for dogs
Butterfly catheter and 60ml syringes
Used for blooc collection in cats
Diphenhydramine (2mg/kg) IM/IV
Premedication for transfusiin
Dexanethasone (2mg/kg) IV
Post medication for blood transfusion
