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C
A differential count reflects
Option A: the ratio of antibody types.
Option B: the ratio of red blood cell types.
Option C: the ratio of white blood cell types.
Option D: the ratio of platelet types.
B
What component of the blood contains the most antibodies?
Option A: platelets
Option B: gamma globulin
Option C: white blood cells
Option D: complement
D
Which of the following is a primary (central) immune structure?
Option A: Lymph nodes
Option B: Tonsils
Option C: Blood cells
Option D: Thymus
C
__________ act(s) as the "eyes" and "ears" of the cell during communication involved with the immune response?
Option A: Interferon
Option B: Cytokines
Option C: Surface receptors
Option D: Adhesion molecules
D
The myeloid lineage does NOT lead to
Option A: red blood cells.
Option B: leukocytes.
Option C: platelets.
Option D: lymphocytes.
B
Complement activation can lead to ____________________________.
Option A: Lysis of a target cell via lactoferrin activation
Option B: Chemotaxis of phagocytes to the site of infection
Option C: Prevention of inflammation
Option D: Diminished phagocytosis
C
The engulfment stage of phagocytosis involves _____________ surrounding the invader and forming a phagosome.
Option A: Phagolysosomes
Option B: Chemoattractants
Option C: Pseudopods
Option D: Lysosomes
D
________________ is a nonspecific defense mechanism by which monocytes and neutrophils engulf and destroy foreign substances.
Option A: Inflammation
Option B: Antibody production
Option C: none of the above
Option D: Phagocytosis
A
__________________ interferes with viral replication.
Option A: Interferon
Option B
Complement proteins
Option C
Globulin fraction
Option D
All of the above
A
The purpose of complement is to
Option A: Two of the above
Option B: Lyse invader cells
Option C: Enhance phagocytosis
Option D: Serve as a barrier to infection
A
Which of the following statements best describes the innate branch of the immune system?
Option A: You are born with the components of the innate immune system, and it is responsible for an immediate and general response to invaders
Option B: The innate immune system develops over a person's lifetime and prevents external microbes form gaining access to the body
Option C: You are born with the components of the innate immune system, and it is responsible for a specific response to invaders
Option D: The innate immune system develops over a person's lifetime and tries to eliminate microbes that gain access to the body
C
What does it mean that the immune system needs to recognize "self" from "non-self"?
Option A: Immune cells should attack healthy body cells
Option B: Immune cells need to be able to recognize themselves
Option C: Immune cells should only recognize and attack invaders/infected cells
Option D: Immune cells should only recognize microbes
D
What part of innate immune cells is capable of recognizing invaders?
Option A: Pathogen-associated molecular patterns
Option B: Spike proteins
Option C: Complement binding activators
Option D: Pattern recognition receptors
B
The lymphoid pathway of blood cell maturation is responsible for what cells? Option A
Option A: Platelets and Red Blood cells
Option B: T cells and B cells
Option C: Monocytes and neutrophils
Option D: Eosinophils and basophils
A
Which of the following is NOT one of the ways the microbiota contributes to the innate immune system?
Option A: Creation of antibiotics
Option B: Competes with pathogens for space/nutrients
Option C: Immune stimulation
Option D: Secretion of toxins to ward off pathogens
D
Which of the following correctly states one of the outcomes of the complement pathway? Option A
Option A: Activation of B cells
Option B: Prevention of inflammation
Option C: Restriction of phagocytosis
Option D: Lysis of a target cell
B
You are studying macrophages in the laboratory to examine the process of phagocytosis. When you look at your sample under the microscope you see a macrophage that has pseudopods surrounding a bacterial cell. What stage of phagocytosis are you witnessing?
Option A: Phagosome maturation
Option B: Engulfment
Option C: Destruction/Digestion
Option D: Chemotaxis
A
Which of the following is NOT one of the cardinal signs of inflammation?
Option A: Tissue damage
Option B: Redness
Option C: Heat
Option D: Swelling
Option E: Pain
B
If you were trying to determine the ratio of white blood cell types in a patient, you should order
Option A: A PAMP pane
Option B: A differential count
Option C: A complement blood count
Option D: A neutrophil panel
B
Immune cells in a person infected with COVID-19 would be releasing ______, which acts as an antiviral and would aid in interfering with COVID-19 replication.
Option A: Complement proteins
Option B: Interferons
Option C: Globulins in blood
Option D: All of the above
B
T cells and B cells are associated with
Option A: Pattern recognition receptors
Option B: The adaptive immune system
Option C: The innate immune system
Option D: The microbiome
D
If the immune system wanted to induce growth and differentiation of immune cells, _____ should be released
Option A: Lysozymes
Option B: Antibodies
Option C: Chemoattractants
Option D: Cytokines
C
The thymus is the structure primarily responsible for
Option A: The site of hematopoiesis
Option B: Creation of platelets and red blood cells
Option C: Maturation of T cells
Option D: Maturation of B cells
A, C, D
How do mucous membranes function as a mechanical/chemical barrier? Select all that apply
Option A: Peristalsis removes microbes
Option B: Secretion of toxins to defend against pathogens
Option C: Acidity of the stomach acid kills microbes
Option D: Secrete antimicrobial peptides
B
Lysozymes found in your tears, saliva, and blood are most effective against
Option A: Viruses
Option B: Bacteria
Option C: Fungi
Option D: Protozoa
C
Complement system can be activated by
Option A: The innate immune system only
Option B: The adaptive immune system only
Option C: Both the innate and adaptive immune system
Option D: Neither the innate or adaptive immune system
C
If clotting factors are walling off the site of the infection, you are in the ______ stage of the inflammatory process.
Option A:1st
Option B: 2nd
Option C: 3rd
Option D: 4th
C
A B cell recognizes and binds to the LPS of an E. coli cell using it's B cell receptor. In this case, the B cell receptor would be considered a
Option A: Pathogen associated molecular pattern
Option B: Cytokine
Option C: Pattern recognition receptor
Option D: Antigen
A, B, D
Correctly identify the how fever acts as a host defense mechanism. Check all that apply: ?
Option A: Enhances the inflammatory response
Option B: Enhances antibody production
Option C: Enhances chemotaxis of phagocytes and phagocytosis
Option D: Enhances multiplication of lymphocytes
C
Which statement correctly explains the relationship of the normal microbiota with the innate immune system?
Option A: The normal microbiota inhibits the immune system by releasing chemoattractants that stop phagocytes
Option B: The normal microbiota secretes toxins that help to stimulate macrophages
Option C: The normal microbiota competes with pathogens for space and nutrients
Option D: The normal microbiota produces lysozyme to degrade the peptidoglycan of pathogens
A
A cancer patient is undergoing surgery to remove a tumor, and several lymph nodes surrounding it. The removal of the lymph nodes would likely have what effect?
Option A: The patient would produce less antibodies at the site where the lymph nodes were removed
Option B: The patient would have a greater number of B cells at the site where the lymph nodes were removed
Option C: The patient would have a greater number of phagocytic cells at the site where the lymph nodes were removed
Option D: The patient would produce less interferons at the site where the lymph nodes were removed