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Skeletal muscle
attached to bones
voluntary
striated
body movement, posture, and joint stability
Smooth muscle
in walls of hollow organs (stomach, intestines, blood vessels) and in the iris of the eye
involuntary
controls internal movements like digestion, breathing, and circulation
Cardiac muscle
in the heart
involuntary
contracts rhythmically to pump blood throughout the body; cross-fibered structure allows coordinated contraction.
Functions of muscles
movement: voluntary and involuntary actions
posture and balance
circulation
heat production: muscle activity generates heat, helping maintain body temperature
Tendons
tough cords of connective tissue that attach muscles to bones
help transfer the force of muscle contraction to create movement
Ligaments
work with muscles to stabilize joints and prevent excessive movement
Role of lymphatic and immune system
work together to protect the body from infection, illness, and disease
transport network for immune cells and helps remove waste, toxins, and excess fluid from tissues
Lymph nodes
small, bean-shaped glands located in the neck, armpits, and groin
filter lymph fluid, trapping bacteria and viruses
produce and store lymphocytes and macrophages that destroy harmful substances
Lymph nodules
small masses of lymph tissue that are not enclosed by a capsule
contain lymphocytes and macrophages that help fight infections
Thymus
located behind the sternum
large in children, shrinks with age
produces and matures T-cells, a type of white blood cell critical for immune defense
Spleen
largest lymph organ
upper-left side of the abdomen
filters blood, removes old red blood cells, and houses immune cells that detect and destroy pathogens
Interstitial Fluid (Lymph)
fluid found between cells; becomes lymph once collected into lymphatic vessels
transports immune cells and waste products through the lymphatic system
How does the immune system work?
defends the body by recognizing and responding to antigens—foreign substances such as bacteria, viruses, or toxins.
Antigen
A foreign substance that triggers an immune response
Antibody
A protein made by the immune system to target and neutralize specific antigens
B cells
Recognize antigens and produce antibodies that help destroy invaders
T cells
Attack and destroy infected or abnormal cells directly
Monocytes
Large white blood cells that engulf and destroy pathogens marked by antibodies
Naturally acquired immunity
developing antibodies after recovering from an illness
long-term
Artificially Acquired Active Immunity
Receiving a vaccination that stimulates antibody production
long-term
Naturally Acquired Passive Immunity
Passing antibodies from mother to baby through the placenta or breast milk
short-term
Artificially Acquired Passive Immunity
Receiving ready-made antibodies (e.g., immune globulin after exposure)
short-term
What is the cardiovascular system responsible for?
transporting blood, oxygen, nutrients, and waste throughout the body
What makes up the cardiovascular system?
heart
blood vessels
blood
Heart
a muscular organ located in the chest (mediastinum)
pumps blood throughout the body to deliver oxygen and remove waste
Arteries/arterioles
thick-walled vessels that carry blood away from the heart
propel oxygenated blood to the body
arterioles are smaller branches of arteries
Veins/venules
thin-walled vessels that carry blood toward the heart
transport deoxygenated blood
contain valves to prevent backflow
Capillaries
Microscopic vessels connecting arteries and veins
Allow exchange of oxygen, nutrients, and waste between blood and body tissues
Endocardium
Inner lining of the heart chambers and valves
Smooth surface to reduce friction and protect tissue
Myocardium
Thick, muscular middle layer of the heart
Responsible for the pumping action of the heart
Pericardium
Outer protective membrane around the heart
Reduces friction and protects the heart from surrounding organs
Right atrium
Receives deoxygenated blood from the body via the superior and inferior vena cava
Right ventricle
Pumps blood through the pulmonary valve to the lungs via the pulmonary artery for oxygen exchange
Left atrium
Receives oxygenated blood from the lungs through the pulmonary veins (the only veins that carry oxygenated blood)
Left ventricle
Pumps oxygenated blood through the aortic valve into the aorta, sending it throughout the body
Heart valves
ensure that blood flows in one direction and prevent backflow
tricuspid
pulmonary
mitral (bicuspid)
aortic
Pulmonary circulation
Moves blood between the heart and lungs to exchange carbon dioxide for oxygen
Systemic circulation
Moves oxygenated blood from the heart to the body and returns deoxygenated blood back to the heart
Hearts electrical system/ cardiac cycle
The Sinoatrial (SA) Node, known as the pacemaker, spontaneously generates the electrical impulse
The electrical wave sweeps across the two upper chambers , causing the atria to squeeze and push blood down into the lower chambers
The impulse travels to the Atrioventricular (AV) Node, which delays it slightly to allow the atria to contract
it continues from the AV node to the Bundle of His and bundle branches down the ventricular septum
Finally, it spreads to the Purkinje fibers, causing the ventricles to contract and pump blood.
How often does the cardiac cycle repeat?
repeats about 60–80 times per minute at rest